US5003977A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for analyzing fluorescent light signals
Assignee: National Institute of Advanced Industrial Science and Technology
•
Filing: 1989-03-09
•
Granted: 1991-04-02
•
Expires: 2009-03-09
Abstract
Abstract A device for analyzing fluorescent light signals consists of memory means for storing as a reference spectrum a spectrum obtained under predetermined conditions, and extraction means for extracting a predetermined component spectrum based on the results of a conversion of the reference spectrum using a specific wavelength of a measured spectrum obtained during actual measurement and a specific wavelength of the reference spectrum. The arrangement of the invention allows the spectrum of a specific component to be extracted accurately from measured spectra.
Inventors
- 👤 Susumu Suzuki
- 👤 Kazuyuki Ishida
- 👤 Takeo Ozaki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:35
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/17; G01N21/25; G01N21/27; G01N21/274; A; A61; A61B; A61B5/00; A61B5/0059; A61B5/0071; A61B5/0082; A61B5/0084; G01N21/62; G01N21/63; G01N21/64; A61B5/0075; G01J; G01J3/00; G01J3/28; G01J2003/2866; G01J2003/2873; G01J3/44; G01J3/4406; G01N2021/6417; G01N21/645; G01N21/6456; G01N21/6458
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
171 words
A device for analyzing fluorescent light signals, comprising: first light-irradiating means for irradiating a normal position of an organism with first laser light; first light-detecting means for detecting a first spectrum of fluorescence excited by the irradiation of said first laser light; memory means for storing, as a reference spectrum, the first spectrum of fluorescence detected by said first light-detecting means; second light-irradiating means for irradiating with second laser light a position to be diagnosed of the organism injected with a fluorescent substance having a strong affinity for tumors; second light-detecting means for detecting a second spectrum of fluorescence excited by the irradiation of said second laser light; correction means for correcting said reference spectrum on the basis of a ratio of an intensity of a specific wavelength in the second spectrum detected by said second light-detecting means to an intensity of the same wavelength as said specific wavelength in said reference spectrum; and extraction means for subtracting the corrected reference spectrum from the detected second spectrum and extracting the difference.
Claim 2
Independent Claim
171 words
A device for analyzing fluorescent light signals, comprising: first light-irradiating means for irradiating a normal position of an organism with first laser light; first light-detecting means for detecting a first spectrum of fluorescence excited by the irradiation of said first laser light; memory means for storing, as a reference spectrum, the first spectrum of fluorescence detected by said first light-detecting means; second light-irradiating means for irradiating with second laser light a position to be diagnosed of the organism injected with a fluorescent substance having a strong affinity for tumors; second light-detecting means for detecting a second spectrum of fluorescence excited by the irradiation of said second laser light; correction means for correcting said reference spectrum on the basis of a ratio of an intensity of a specific wavelength in the second spectrum detected by said second light-detecting means to an intensity of the same wavelength as said specific wavelength in said reference spectrum; and extraction means for subtracting the corrected reference spectrum from the detected second spectrum and extracting the difference.
Claim 3
Independent Claim
174 words
A device for analyzing fluorescent light signals, comprising: light-irradiating means for irradiating with a laser a normal position of an organism and a position to be diagnosed of said organism injected with a fluorescent substance having a strong affinity for tumors; light-detecting means for detecting a first spectrum of fluorescence excited by irradiation of said normal position by said light-irradiating means and a second spectrum of fluorescence excited by irradiation of said diagnosed position by said light-irradiating means; first memory means for storing said first spectrum, said first spectrum being used as a reference spectrum; second memory means for storing an intensity at a wavelength in said first spectrum and for storing an intensity of said wavelength in said second spectrum; correction means for correcting said reference spectrum by multiplying said reference spectrum by a ratio of said intensity at said wavelength in said first spectrum to said intensity at said second wavelength in said spectrum; and extraction means for subtracting said corrected reference spectrum from said second spectrum and for outputting the difference.
Claim 4
Independent Claim
174 words
A device for analyzing fluorescent light signals, comprising: light-irradiating means for irradiating with a laser a normal position of an organism and a position to be diagnosed of said organism injected with a fluorescent substance having a strong affinity for tumors; light-detecting means for detecting a first spectrum of fluorescence excited by irradiation of said normal position by said light-irradiating means and a second spectrum of fluorescence excited by irradiation of said diagnosed position by said light-irradiating means; first memory means for storing said first spectrum, said first spectrum being used as a reference spectrum; second memory means for storing an intensity at a wavelength in said first spectrum and for storing an intensity of said wavelength in said second spectrum; correction means for correcting said reference spectrum by multiplying said reference spectrum by a ratio of said intensity at said wavelength in said first spectrum to said intensity at said second wavelength in said spectrum; and extraction means for subtracting said corrected reference spectrum from said second spectrum and for outputting the difference.
Claim 5
Dependent Claim
26 words
A device as recited in claim 2, wherein: said first spectrum at said wavelength has a much greater intensity than said second spectrum at said wavelength.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-01 | 1994-10-01 | 1995-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-01 | 1998-10-01 | 1999-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-01 | 2002-10-01 | 2003-04-02 | $7700.00 | Window Closed / Lapsed |