Patent US4997653A successfully refreshed from Google Patents.
US4997653A
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US
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Method for treating endometriosis with topical preparations containing danazol
Assignee: Tanabe Pharma Corp
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Filing: 1988-12-20
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Granted: 1991-03-05
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Expires: 2008-12-20
Abstract
Abstract A topical preparation of danazol comprising a matrix base, danazol retained therein, and optionally a release-promoting agent is provided. The topical preparation is more effective than oral administration of danazol in the shrinkage of endometriosis tissue, the induction of pregnancy, and the like. It does not show any side effects that have been encountered in the oral administration of danazol. Thus, the preparation is very useful remedy for endometriosis.
Inventors
- 👤 Masao Igarashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 17:51
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/58; A61K9/00; A61K9/0012; A61K9/0034; A61K9/0036; A61K9/0039; A61P; A61P13/00; A61P13/02; A61P15/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
28 words
A method of treating endometriosis comprising a topical pharmaceutical composition of danazol comprising a matrix base topical drug delivery system and an effective amount of danazol retained therein.
Claim 2
Independent Claim
28 words
A method of treating endometriosis comprising a topical pharmaceutical composition of danazol comprising a matrix base topical drug delivery system and an effective amount of danazol retained therein.
Claim 3
Dependent Claim
12 words
Method of claim 1 wherein said endometriosis is pelvic endometriosis or adenomyosis.
Claim 4
Dependent Claim
13 words
Method of claim 1 wherein said preparation is inserted into a uterine cavity.
Claim 5
Dependent Claim
12 words
Method of claim 1 wherein said preparation is inserted into a vagina.
Claim 6
Independent Claim
31 words
A method of treating endometriosis comprising a topical pharmaceutical composition of danazol comprising a matrix base topical drug delivery system and an effective amount of danazol retained therein, and release-promoting agent.
Claim 7
Independent Claim
31 words
A method of treating endometriosis comprising a topical pharmaceutical composition of danazol comprising a matrix base topical drug delivery system and an effective amount of danazol retained therein, and release-promoting agent.
Claim 8
Dependent Claim
15 words
A method as claimed in claim 5 wherein said endometriosis is pelvic endometriosis or adenomyosis.
Claim 9
Dependent Claim
16 words
A method as claimed in claim 5 wherein said preparation is inserted into a uterine cavity.
Claim 10
Dependent Claim
15 words
A method as claimed in claim 5 wherein said preparation is inserted into a vagina.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-03-04 | 1994-09-03 | 1995-03-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-03-04 | 1998-09-03 | 1999-03-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-03-04 | 2002-09-03 | 2003-03-05 | $7700.00 | Window Closed / Lapsed |