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US4991092A Expired / Lapsed US ⏱️ 0.0 years remaining

Image processor for enhancing contrast between subregions of a region of interest

Assignee: CALIFORNIA A CORP OF CA, University of, Regents of
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Filing: 1988-08-12
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Granted: 1991-02-05
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Expires: 2008-08-12
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Abstract

Abstract An imaging technique is disclosed for enhancing the contrast of an image, in particular for enhancing the contrast between subregions of a region of interest which may have similar signal characteristics and significantly distinct physical properties. A distribution density function describing the density of the signal in a signal space assigned to a voxel of the region to be imaged is first computed. This distribution function is then convolved with a resolution function, preferably a Gaussian function. Advantageously, the variance of the Gaussian is greater and a multiple of the variance of the noise statistics of the input image. The result of the convolution of the distribution function with the resolution function defines a scale, preferably a grey scale which assigns a particular tone to a pixel of the image corresponding to the voxel of the region to be imaged. The standard deviation is preferably chosen by the user and defines the resolution of the final image in the signal space. The noise in the output image can be decreased by increasing the standard deviation of the convolving Gaussian. For large values of the variance of the Gaussian, the contrast-to-noise ratio is comparable to standard images. The resulting gray scale creates a greater contrast between areas of different volumes having similar signal characteristics. Other resolution functions can be used.

Inventors

  • 👤 Fred Greensite

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 12:21
CPC Classifications
G; G06; G06T; G06T5/00; G06T5/40; G06T5/10; G06T5/90; G06T5/92; G06T2207/00; G06T2207/10; G06T2207/10072; G06T2207/10081; G06T2207/10088; G06T2207/10116; G06T2207/20; G06T2207/20048; G06T2207/20056

Claims Analysis

Total Claims: 38
Claim 1
Independent Claim 104 words
A method for processing an image, said image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said method comprising the steps of: providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M; computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; and assigning a tone value to each of said plurality of voxels in accordance with said density function
Claim 2
Independent Claim 104 words
A method for processing an image, said image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said method comprising the steps of: providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M; computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; and assigning a tone value to each of said plurality of voxels in accordance with said density function
Claim 3
Independent Claim 184 words
A method for processing an image, said image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, comprising the steps of: providing a plurality of multidimensional signals, each of said multidimensional signals comprising a plurality of parameters containing information about said region of interest, each of said signals being further associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable having a density function; computing said density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; convolving said density function with a resolution function so as to provide a real valued probability density function defined for each of said plurality of voxels; assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 4
Independent Claim 184 words
A method for processing an image, said image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, comprising the steps of: providing a plurality of multidimensional signals, each of said multidimensional signals comprising a plurality of parameters containing information about said region of interest, each of said signals being further associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable having a density function; computing said density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; convolving said density function with a resolution function so as to provide a real valued probability density function defined for each of said plurality of voxels; assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 5
Dependent Claim 33 words
A method for processing an image as defined in claim 2, wherein said convolving step comprises the step of convolving a Gaussian function of mean zero and variance σ with said density function
Claim 6
Dependent Claim 35 words
A method for processing an image as defined in claim 3, wherein said Gaussian has a variance σ equal to or greater than the variance ν of said density function of said signal mapping M.
Claim 7
Dependent Claim 34 words
A method for processing an image as defined in claim 4, wherein said variance σ of said Gaussian is a multiple of said variance ν of said density function of said signal mapping M.
Claim 8
Dependent Claim 70 words
A method for processing an image as defined in claim 3, wherein said variance σ defines the resolution of said image in said signal space, whereby high values of the variance σ with respect to the variance ν produce a low resolution image in said signal space and whereby low values of the variance σ with respect to the variance σ produce a high resolution image in said signal space.
Claim 9
Dependent Claim 50 words
A method for processing an image as defined in claim 3, wherein said image has a contrast defined by said tone value and said signal space is defined with a metric, said contrast between two voxels of said plurality of voxels being independent on the metric in said signal space.
Claim 10
Dependent Claim 31 words
A method for processing an image as defined in claim 2, wherein said convolving step includes the step of convolving a cosine function with said density function of said mapping M.
Claim 11
Dependent Claim 35 words
A method for processing an image as defined in claim 2, wherein said convolving step includes the step of convolving a pulse function having a width σ with said density function of said mapping M.
Claim 12
Dependent Claim 31 words
A method for processing an image as defined in claim 2, wherein said convolving step includes the step of convolving a sinc function with said density function of said mapping M.
Claim 13
Dependent Claim 31 words
A method for processing an image as defined in claim 2, wherein said convolving step includes the step of convolving an exponential function with said density function of said mapping M.
Claim 14
Dependent Claim 31 words
A method for processing an image as defined in claim 2, wherein said convolving step includes the step of convolving a filter function with said density function of said mapping M.
Claim 15
Dependent Claim 59 words
A method for processing an image as defined in claim 2, wherein said density function is given by the following formula: ##EQU14## wherein δ is the delta function, where w is the voxel in the set of voxels comprising said region of interest, and s is any possible signal value that a voxel could have as its measured value.
Claim 16
Dependent Claim 20 words
A method for processing an image as defined in claim 2, wherein said convolution product is performed using Fourier transforms.
Claim 17
Dependent Claim 21 words
A method for processing an image as defined in claim 2, wherein said convolution product is performed using Fast Fourier transforms.
Claim 18
Dependent Claim 64 words
A method for processing an image as defined in claim 2, wherein said probability density function is given by the following equation: Hσ(s)=Gσ(s)*H.sub.o (s), wherein * denoted the convolution product, Gσ(s) represents said distribution function and H o (s) represents the density function of same mapping M, and where σ is any real number, σ being the standard deviation of said distribution function Gσ(s).
Claim 19
Dependent Claim 18 words
A method for processing an image as defined in claim 2, wherein said image is a medical image
Claim 20
Dependent Claim 17 words
A method for processing an image as defined in claim 2, wherein said signals are NMR signals.
Claim 21
Dependent Claim 19 words
A method for processing an image as defined in claim 2, wherein said signals are obtained by computer tomography.
Claim 22
Dependent Claim 24 words
A method for processing an image as defined in claim 2, wherein said signals are obtained from X-ray projections of said region of interest.
Claim 23
Dependent Claim 19 words
A method for processing an image as defined in claim 2, wherein said tone value is a grey value.
Claim 24
Dependent Claim 18 words
A method for processing an image as defined in claim 2, wherein said tone value is a color.
Claim 25
Dependent Claim 23 words
A method for processing an image as defined in claim 2, wherein said step of assigning a tone value is performed by segmentation.
Claim 26
Dependent Claim 40 words
A method for processing an image as defined in claim 2, wherein said convolving step is performed by using a multidimensional resolution function so as to obtain a single image incorporating said information from all of said plurality of parameters.
Claim 27
Dependent Claim 47 words
A method for processing an image as defined in claim 2, wherein said convolving step is performed by using a plurality of unidimensional resolution functions so as to obtain a plurality of images corresponding to each of said parameters of said multidimensional signals in said signal space.
Claim 28
Independent Claim 145 words
A method for processing an image, said method comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, comprising the steps of: providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; computing the Radon-Nikodym derivative of said probability measure of said mapping M, said Radon-Nikodym derivative defining a probability density function; assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 29
Independent Claim 145 words
A method for processing an image, said method comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, comprising the steps of: providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; computing the Radon-Nikodym derivative of said probability measure of said mapping M, said Radon-Nikodym derivative defining a probability density function; assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 30
Independent Claim 181 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; means for convolving said density function with a resolution function so as to provide a real valued probability density function defined for each of said plurality of voxels; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 31
Independent Claim 181 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; means for convolving said density function with a resolution function so as to provide a real valued probability density function defined for each of said plurality of voxels; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 32
Independent Claim 153 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing the Radon-Nikodym derivative of said probability measure of said mapping M, said Radon-Nikodym derivative defining a probability density function; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 33
Independent Claim 153 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing the Radon-Nikodym derivative of said probability measure of said mapping M, said Radon-Nikodym derivative defining a probability density function; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 34
Independent Claim 153 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 35
Independent Claim 153 words
An apparatus for processing an image comprising a plurality of pixels representing a region of interest partitioned into a plurality of voxels, said apparatus comprising: an input imaging device for providing a plurality of multidimensional signals, each of said signals being associated with each of said voxels, said plurality of voxels being mapped into said plurality of signals in a signal space by a mapping M, said mapping M being a multidimensional random variable and defining a probability measure in said signal space; means for computing a density function representative of the frequency of occurrence of each of said multidimensional signals in said signal space; means for assigning a tone value to each of said plurality of voxels corresponding to the value of said probability density function for each of said voxels; and means for displaying a tone level image wherein each voxel is represented by a pixel with said assigned tone value.
Claim 36
Dependent Claim 19 words
An apparatus for processing an image according to claim 29, wherein said input imaging device is a NMR device.
Claim 37
Dependent Claim 19 words
An apparatus for processing an image according to claim 29, wherein said input imaging device is an X-ray camera.
Claim 38
Dependent Claim 19 words
An apparatus for processing an image according to claim 29, wherein said input imaging device is a CT device.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-02-04 1994-08-06 1995-02-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-02-04 1998-08-06 1999-02-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-02-04 2002-08-06 2003-02-05 $7700.00 Window Closed / Lapsed

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