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US4987371A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for in-vivo shimming

Assignee: General Electric Co
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Filing: 1989-11-27
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Granted: 1991-01-22
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Expires: 2009-11-27
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Abstract

Abstract In-vivo shimming is performed by acquiring two NMR images with evolution times differing by ##EQU1## where ω 1 , ω 2 , are the Larmor frequencies of the dominant proton species of the imaged object. A pixel by pixel division of the image yields a third image whose phase is proportional to magnetic field inhomogeneity. The phase of the third image set has periodic discontinuities as a result of the periodicity of the arctangent function used to extract the phase from the image. These discontinuities are removed by taking the derivative of the phase and integrating the product of that derivative and a weighting function where the weighting function has zero weight at the points of discontinuity. Off-center quadratic terms in the inhomogeneity are removed prior to fitting the linear shimming gradients.

Inventors

  • 👤 Gary H. Glover
  • 👤 Erika Schneider

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 15:48
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; G01R33/38; G01R33/387; G01R33/3875; G01R33/24

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 142 words
A method of determining the spatial variation of magnetic field strength within an imaged object placed in a polarizing magnetic field, said imaged object including a first and second material with a first and second Larmor frequency, ω 1 , ω 2 , comprising the steps of: acquiring a first NMR view set with a first evolution time t E1 ; acquiring a second NMR view set with a second evolution time t E2 such that, for integers n, ##EQU11## reconstructing a first and second complex multipixel image from each NMR view set; dividing each pixel of the first complex multiplexel image by the corresponding pixel of the second multipixel image, on a pixel by pixel basis, to produce a complex multiplexel ratio image; and calculating the argument of each pixel of the complex multipixel ratio image to produce an inhomogeneity map.
Claim 2
Independent Claim 142 words
A method of determining the spatial variation of magnetic field strength within an imaged object placed in a polarizing magnetic field, said imaged object including a first and second material with a first and second Larmor frequency, ω 1 , ω 2 , comprising the steps of: acquiring a first NMR view set with a first evolution time t E1 ; acquiring a second NMR view set with a second evolution time t E2 such that, for integers n, ##EQU11## reconstructing a first and second complex multipixel image from each NMR view set; dividing each pixel of the first complex multiplexel image by the corresponding pixel of the second multipixel image, on a pixel by pixel basis, to produce a complex multiplexel ratio image; and calculating the argument of each pixel of the complex multipixel ratio image to produce an inhomogeneity map.
Claim 3
Dependent Claim 18 words
The method of claim 1 where the NMR view sets are acquired by a gradient echo pulse sequence.
Claim 4
Dependent Claim 18 words
The method of claim 1 where the NMR view sets are acquired by a spin echo pulse sequence.
Claim 5
Dependent Claim 7 words
The method of claim 1 wherein n=1.
Claim 6
Independent Claim 76 words
A method of calculating shimming gradients from an inhomogeneity map comprising the steps of: (a) taking the partial derivative of the inhomogeneity map along a shimming axis to produce a differentiated inhomogeneity map; (b) producing a discontinuity weighting function that assigns zero weight to points of the differentiated inhomogeneity map that have values outside of a predetermined range; and (c) performing a weighted curve fitting to the differentiated inhomogeneity map to determine a correcting shimming field.
Claim 7
Independent Claim 76 words
A method of calculating shimming gradients from an inhomogeneity map comprising the steps of: (a) taking the partial derivative of the inhomogeneity map along a shimming axis to produce a differentiated inhomogeneity map; (b) producing a discontinuity weighting function that assigns zero weight to points of the differentiated inhomogeneity map that have values outside of a predetermined range; and (c) performing a weighted curve fitting to the differentiated inhomogeneity map to determine a correcting shimming field.
Claim 8
Dependent Claim 28 words
The method of claim 5 including the step of integrating the differentiated inhomogeneity map along an axis perpendicular to the shimming axis prior to the weighted curve fitting.
Claim 9
Dependent Claim 53 words
The method of claim 5 including the additional step of: generating an amplitude weighting function that assigns weight to points of the differentiated inhomogeneity map in proportion to the magnitude of value of the image at the points; and using both the amplitude weighting function and the discontinuity weighting function in step (d).
Claim 10
Dependent Claim 51 words
The method of claim 5 including the additional step of: generating an amplitude weighting function that assigns weight to points of the differentiated inhomogeneity map in proportion to the power of the image at the points; and using both the amplitude weighting function and the discontinuity weighting function in step (d).
Claim 11
Dependent Claim 51 words
The method of claim 5 including the additional step of: generating an amplitude weighting function that assigns zero weight to points of the differentiated inhomogeneity map that have values with a magnitude less than a predetermined threshold; and using the amplitude weighting function and the discontinuity weighting function in step (d).
Claim 12
Independent Claim 71 words
A method of correcting a magnetic field represented by an inhomogeneity map by means of a shim coil producing a low order compensating shim gradient having a center, the magnetic field having a low order inhomogeneity and an off-center higher order inhomogeneity, comprising the steps of identifying the spatial location of the higher order component along an axis and adjusting the compensating shim gradient to correct the low order inhomogeneity only.
Claim 13
Independent Claim 71 words
A method of correcting a magnetic field represented by an inhomogeneity map by means of a shim coil producing a low order compensating shim gradient having a center, the magnetic field having a low order inhomogeneity and an off-center higher order inhomogeneity, comprising the steps of identifying the spatial location of the higher order component along an axis and adjusting the compensating shim gradient to correct the low order inhomogeneity only.
Claim 14
Dependent Claim 19 words
The method of claim 10 where the low order inhomogeneity is linear and the higher order inhomogeneity is quadratic.
Claim 15
Dependent Claim 27 words
The method of claim 10 where the spatial location of the off-center higher order inhomogeneity is determined by calculating the center of mass of the slice image.
Claim 16
Independent Claim 88 words
A method of correcting a magnetic field having an off-center quadratic component at x 0 resulting from an imaged object, by means of a shim coil producing a linear shim gradient, comprising the steps of: determining a linear coefficient α 1 and a quadratic coefficient α 2 of the magnetic field along an axis; determining the center of the quadratic term x 0 with respect to the axis; and setting the slope of the shim gradient along the axis equal to α 1 +α 2 x 0 .
Claim 17
Independent Claim 88 words
A method of correcting a magnetic field having an off-center quadratic component at x 0 resulting from an imaged object, by means of a shim coil producing a linear shim gradient, comprising the steps of: determining a linear coefficient α 1 and a quadratic coefficient α 2 of the magnetic field along an axis; determining the center of the quadratic term x 0 with respect to the axis; and setting the slope of the shim gradient along the axis equal to α 1 +α 2 x 0 .
Claim 18
Dependent Claim 27 words
The method of claim 13 where the center of the quadratic term is set equal to the center of mass of the image of the imaged object.

References Cited (Backward Citations)

US4585992A Cited
US4749948A Cited
US4523166A Cited
US4720679A Cited
US4733189A Cited
US4761614A Cited
US4949044A Cited
US4899109A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-01-21 1994-07-23 1995-01-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-01-21 1998-07-23 1999-01-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-01-21 2002-07-23 2003-01-22 $7700.00 Window Closed / Lapsed

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