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US4977276A Expired / Lapsed US ⏱️ 0.0 years remaining

Heteroarotinoids as anticancer agents

Assignee: Oklahoma State University
•
Filing: 1989-12-28
•
Granted: 1990-12-11
•
Expires: 2009-12-28
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Abstract

Abstract Novel heteroarotinoid compositions characterized by the formulae: <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> where: X is S or O; OAc is the acetate group <IMAGE> and R is -H, -OH, -OCH3, or -OC2H5 and includes <IMAGE> for formulae (1) and (2). Such compositions exhibit activity as anticancer agents.

Inventors

  • 👤 Kenneth D. Berlin
  • 👤 Warren T. Ford
  • 👤 Shirish N. Rajadhyaksha
  • 👤 Jonathan B. Gale
  • 👤 Lyle W. Spruce

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 19:29
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D311/00; C07D311/02; C07D311/04; C07D311/58; C07D333/00; C07D333/50; C07D333/52; C07D333/54; C07D335/00; C07D335/04; C07D335/06; C07D407/00; C07D407/02; C07D407/06; C07D409/00; C07D409/02; C07D409/12

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 26 words
A heteroarotinoid characterized by the formulae: ##STR38## where X is S or O; and R is --H, --OH, --OCH 3 or --OC 2 H 5 .
Claim 2
Dependent Claim 26 words
A heteroarotinoid characterized by the formulae: ##STR38## where X is S or O; and R is --H, --OH, --OCH 3 or --OC 2 H 5 .
Claim 3
Dependent Claim 13 words
A heteroarotinoid of claim 1 where X is S and R is --H.
Claim 4
Dependent Claim 13 words
A heteroarotinoid of claim 1 where X is S and R is --OH.
Claim 5
Dependent Claim 15 words
A heteroarotinoid of claim 1 where X is S and R is --OCH 3 .
Claim 6
Dependent Claim 17 words
A heteroarotinoid of claim 1 where X is S and R is --OC 2 H 5 .
Claim 7
Dependent Claim 13 words
A heteroarotinoid of claim 1 where X is O and R is --H.
Claim 8
Dependent Claim 13 words
A heteroarotinoid of claim 1 where X is O and R is --OH.
Claim 9
Dependent Claim 15 words
A heteroarotinoid of claim 1 where X is O and R is --OCH 3 .
Claim 10
Dependent Claim 17 words
A heteroarotinoid of claim 1 where X is O and R is --OC 2 H 5 .

References Cited (Backward Citations)

US3984440A Cited
US4678793A Cited
US4826984A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-12-10 1994-06-11 1994-12-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-12-10 1998-06-11 1998-12-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-12-10 2002-06-11 2002-12-11 $7700.00 Window Closed / Lapsed

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