US4969906A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone and bony tissue replacement
Assignee: Individual
•
Filing: 1989-03-10
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Granted: 1990-11-13
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Expires: 2009-03-10
Abstract
Abstract A new type of implant for replacement of bone or bony tissue has been developed. The implant is formed of a hydrophilic polymer having a random distribution of single size pores throughout. This hydrophilic polymer is implanted in an uncalcified, or partially calcified, state and is allowed to calcify in place, throughout its entire body, through the random pores. The hydrophilic material can be made from materials such as hydrophilic acrylates and hydrophilic methacrylates.
Inventors
- 👤 Joseph H. Kronman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:09
CPC Classifications
C; C08; C08J; C08J9/00; C08J9/26; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61K; A61K6/00; A61K6/80; A61K6/884; A61K6/887; A61L; A61L27/00; A61L27/14; A61L27/16; A61L27/50; A61L27/56; A61F2/2803; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
169 words
A microporous implant having controlled pore size for replacement of bone or bony calcified tissue comprising a hydrophilic polymeric material having pores, formed before implantation of said implant, of a single controlled pore size randomly distributed throughout substantially all of the body of said implant, said pores comprising a single pore size in a selected range of about 50 to about 200μ in diameter, said pores being formed in said polymeric material by: (a) dispersing water-dissolvable salt crystals of a size corresponding to said single pore size in an unpolymerized monomer of a hydrophilic polymerizable material; (b) polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with salt crystals randomly dispersed throughout substantially all of said implant; (c) subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution in vitro whereby said salt crystals are dissolved, and form said pores in said polymeric material at locations previously occupied by said salt crystals; and (d) shaping said polymeric material into said implant.
Claim 2
Dependent Claim
169 words
A microporous implant having controlled pore size for replacement of bone or bony calcified tissue comprising a hydrophilic polymeric material having pores, formed before implantation of said implant, of a single controlled pore size randomly distributed throughout substantially all of the body of said implant, said pores comprising a single pore size in a selected range of about 50 to about 200μ in diameter, said pores being formed in said polymeric material by: (a) dispersing water-dissolvable salt crystals of a size corresponding to said single pore size in an unpolymerized monomer of a hydrophilic polymerizable material; (b) polymerizing said monomer with said salt crystals dispersed therein to form a polymeric material with salt crystals randomly dispersed throughout substantially all of said implant; (c) subjecting said polymeric material with salt crystals dispersed therein to an aqueous solution in vitro whereby said salt crystals are dissolved, and form said pores in said polymeric material at locations previously occupied by said salt crystals; and (d) shaping said polymeric material into said implant.
Claim 3
Dependent Claim
22 words
The implant of claim 1 wherein said monomer is selected from a group consisting of monomers of hydrophilic acrylates and hydrophilic methacrylates.
Claim 4
Dependent Claim
12 words
The implant of claim 2 wherein said hydrophilic acrylates comprise hydroxyalkyl acrylates.
Claim 5
Dependent Claim
11 words
The implant claim 2 wherein said hydrophilic methacrylates comprise hydroxyalkyl methacrylates.
Claim 6
Dependent Claim
12 words
The implant of claim 4 wherein said hydroxyalkyl methacrylates comprise hydroxyethyl methacrylate.
Claim 7
Dependent Claim
18 words
The implant of claim 5 wherein said hydrophilic polymeric material consists essentially of a homopolymer of hydroxyethyl methacrylate.
Claim 8
Dependent Claim
23 words
The implant of claim 1 wherein said salt crystals are selected from a group consisting of sodium chloride, potassium chloride and calcium chloride.
Claim 9
Dependent Claim
20 words
The implant of claim 1 wherein said hydrophilic polymeric material comprises polyhydroxyethyl methacrylate and said salt crystals comprise sodium chloride.
Claim 10
Dependent Claim
77 words
A synthetic bony tissue implant adapted for dental implantation comprising a shaped, partially calcified microporous hydrophilic polymeric material having pores, formed before implantation, of a single controlled pore size randomly distributed throughout substantially all of the body of said implant, said pores comprising a single pore size selected from a range of about 50 to about 200 μ in diameter, said hydrophilic polymeric material selected from a group consisting of hydrophilic acrylates, hydrophilic methacrylates, and mixtures thereof.
Claim 11
Dependent Claim
77 words
A synthetic bony tissue implant adapted for dental implantation comprising a shaped, partially calcified microporous hydrophilic polymeric material having pores, formed before implantation, of a single controlled pore size randomly distributed throughout substantially all of the body of said implant, said pores comprising a single pore size selected from a range of about 50 to about 200 μ in diameter, said hydrophilic polymeric material selected from a group consisting of hydrophilic acrylates, hydrophilic methacrylates, and mixtures thereof.
Claim 12
Dependent Claim
74 words
The implant of claim 9 wherein said micropores are formed by the method of mixing at least one monomer of said hydrophilic polymeric material with crystals of a water-dissolvable salt, said salt crystals ranging in size from about 50 to about 200 μ in diameter, polymerizing said monomer to form said hydrophilic polymeric material, and dissolving said salt crystals by contacting the resulting hydrophilic polymeric material with an aqueous solution to produce said micropores.
Claim 13
Dependent Claim
23 words
The implant of claim 10 wherein said salt crystals are selected from a group consisting of sodium chloride, potassium chloride and calcium chloride.
Claim 14
Dependent Claim
27 words
The implant of claim 10 wherein the material forming said implant material is partially calcified by implantation in an animal or human host before it is shaped.
Claim 15
Dependent Claim
15 words
The implant of claim 9 wherein said implant is used for replacement of alveolar bone.
Claim 16
Dependent Claim
15 words
The implant of claim 9 wherein said implant is used for replacement of tooth surfaces.
Claim 17
Dependent Claim
13 words
The implant of claim 9 wherein said implant is used for mandibular replacement.
Claim 18
Dependent Claim
14 words
The implant of claim 9 wherein said implant is used for hard palate augmentation.
Claim 19
Dependent Claim
12 words
The implant of claim 9 wherein said hydrophilic acrylates comprises hydroxyalkyl acrylates.
Claim 20
Dependent Claim
12 words
The implant of claim 9 wherein said hydrophilic methacrylates comprise hydroxyalkyl methacrylates.
Claim 21
Dependent Claim
12 words
The implant of claim 18 wherein said hydroxyalkyl methacrylates comprise hydroxyethyl methacrylate.
Claim 22
Dependent Claim
18 words
The implant of claim 1 wherein said implant comprises a synthetic bony tissue implant adapted for cosmetic surgery.
Claim 23
Dependent Claim
22 words
The implant of claim 1 wherein said implant comprises a strong bone implant adapted for replacing or augmenting leg or arm bones.
Claim 24
Dependent Claim
18 words
The implant of claim 1 wherein said implant comprises a digit implant adapted for replacing or augmenting digits.
Claim 25
Dependent Claim
18 words
The implant of claim 1 wherein said implant comprises a joint implant adapted for replacing or augmenting joints.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-11-12 | 1994-05-14 | 1994-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-11-12 | 1998-05-14 | 1998-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-11-12 | 2002-05-14 | 2002-11-13 | $7700.00 | Window Closed / Lapsed |