Patent US4157340A successfully refreshed from Google Patents.
Patent US4968533A successfully refreshed from Google Patents.
US4968533A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of preparing membranes with low protein adsorbability
Assignee: Pall Corp
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Filing: 1987-11-02
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Granted: 1990-11-06
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Expires: 2007-11-02
Abstract
Abstract A method of producing a porous polymeric medium having low adsorbability of amide group-containing materials is provided comprising contacting a porous polymeric substrate having a high affinity for amide group-containing materials with a mixture comprising a polymer having hydroxyl moieties and a cross-linking agent having moieties condensable with the hydroxyl moieties to form a coating of the mixture on the polymeric substrate; removing the coated polymeric substrate from the mixture; and curing the coating on the polymeric substrate to form the porous polymeric medium having low adsorbability of amide group-containing materials.
Inventors
- 👤 Thomas C. Gsell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 01:58
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0088; B01D39/00; B01D39/14; B01D39/16; C; C08; C08J; C08J9/00; C08J9/36; C08J9/40; C08J9/42; C08J2377/00; C08J2377/02; C08J2401/00
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
89 words
A method of producing a porous polymeric medium having low adsorbability of amide group-containing materials comprising: contacting a porous polymeric substrate having a high affinity for amide group-containing materials with a mixture comprising a polymer having hydroxyl moieties and a cross-linking agent having moieties condensable with said hydroxyl moieties to form a coating of said mixture on said polymeric substrate; removing said coated polymeric substrate from said mixture; and curing said coating on said polymeric substrate to form said porous polymeric medium having low adsorbability of amide group-containing materials.
Claim 2
Independent Claim
89 words
A method of producing a porous polymeric medium having low adsorbability of amide group-containing materials comprising: contacting a porous polymeric substrate having a high affinity for amide group-containing materials with a mixture comprising a polymer having hydroxyl moieties and a cross-linking agent having moieties condensable with said hydroxyl moieties to form a coating of said mixture on said polymeric substrate; removing said coated polymeric substrate from said mixture; and curing said coating on said polymeric substrate to form said porous polymeric medium having low adsorbability of amide group-containing materials.
Claim 3
Dependent Claim
19 words
The method of making a porous polymeric medium of claim 1 wherein said porous polymeric substrate comprises a polyamide.
Claim 4
Dependent Claim
17 words
The method of making a porous polymeric medium of claim 2 wherein said polyamide is nylon 66.
Claim 5
Dependent Claim
24 words
The method of making a porous polymeric medium of claim 2 wherein said porous polymeric substrate comprises a skinless, substantially alcohol-insoluble hydrophilic polyamide membrane.
Claim 6
Dependent Claim
20 words
The method of making a porous polymeric medium of claim 1 wherein said polymer coating comprises a cross-linked condensation polymer.
Claim 7
Dependent Claim
31 words
The method of making a porous polymeric medium of claim 5 wherein said cross-linked condensation polymer is formed by a condensation reaction between said hydroxyl group-containing polymer and said cross-linking agent.
Claim 8
Dependent Claim
18 words
The method of making a porous polymeric medium of claim 1 wherein said porous polymeric substrate is microporous.
Claim 9
Dependent Claim
19 words
The method of making a porous polymeric medium of claim 1 wherein said cross-linking agent is a polymeric compound.
Claim 10
Dependent Claim
20 words
The method of making a porous polymeric medium of claim 1 wherein said polymer having hydroxyl moieties is hydroxypropyl cellulose.
Claim 11
Dependent Claim
24 words
The method of making a porous polymeric medium of claim 1 wherein said cross-linking agent is a copolymer of acrylic acid and N-methylol acrylamide.
Claim 12
Dependent Claim
42 words
The method of making a porous polymeric medium of claim 1 wherein said substrate comprises microporous, hydrophilic nylon 66 and said polymer coating is a product formed from the reaction of hydroxypropyl cellulose and a copolymer of acrylic acid and N-methylol acrylamide.
Claim 13
Dependent Claim
32 words
The method of making a porous polymeric medium of claim 1 wherein the affinity for amide group-containing materials of said porous polymeric medium is less than that of said porous polymeric substrate.
Claim 14
Dependent Claim
23 words
The method of making a porous polymeric medium of claim 1 wherein said coating is formed on the surface of said polymeric substrate.
Claim 15
Dependent Claim
20 words
The method of making a porous polymeric medium of claim 1 wherein said porous polymeric substrate comprises a liquophilic material.
Claim 16
Dependent Claim
20 words
The method of making a porous polymeric medium of claim 1 wherein said porous polymeric substrate comprises a hydrophilic material.
Claim 17
Dependent Claim
19 words
The method of making a porous polymeric medium of claim 1 wherein said porous polymeric substrate comprises a membrane.
Claim 18
Dependent Claim
20 words
The method of making a porous polymeric medium of claim 1 wherein said hydroxyl group-containing polymer is a cellulose derivative.
Claim 19
Dependent Claim
21 words
The method of making a porous polymeric medium of claim 17 wherein said cellulose derivative is an hydroxyalkyl ether of cellulose.
Claim 20
Dependent Claim
25 words
The method of making a porous polymeric medium of claim 1 wherein said cross-linking agent has at least two moieties condensable with said hydroxyl moieties.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-11-05 | 1994-05-07 | 1994-11-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-11-05 | 1998-05-07 | 1998-11-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-11-05 | 2002-05-07 | 2002-11-06 | $7700.00 | Window Closed / Lapsed |