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US4946830A Expired / Lapsed US ⏱️ 0.0 years remaining

Agent and method for the prevention of metastases of malignant tumors

Assignee: Individual
•
Filing: 1987-05-01
•
Granted: 1990-08-07
•
Expires: 2007-05-01
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Abstract

Abstract Agents and methods for the prevention of metastases of malignant tumors use the monosaccharides which are specific for organ cell lectins and/or glycoconjugates containing these monosaccharides, and more specifically, β-D-galactose and/or glycoconjugates containing terminal β-D-galactose moieties.

Inventors

  • 👤 Gerhard Pulverer
  • 👤 Kurt Oette
  • 👤 Gerd Uhlenbruck

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 22:31
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/7004; A61P; A61P35/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 52 words
Method for preventing metastases of malignant tumors in a mammal which comprises the administration of an effective amount of a monosaccharide which is specific for organ cell lectins, wherein the monosaccharide is selected from the group consisting of beta-D-galactose, glycoconjugates of beta-D-galactose, mannose, glycoconjugates of mannose, L-fucose, N-acetyl-glucosamine, N-acetylgalactosamine and N-acylneuraminic acid.
Claim 2
Dependent Claim 52 words
Method for preventing metastases of malignant tumors in a mammal which comprises the administration of an effective amount of a monosaccharide which is specific for organ cell lectins, wherein the monosaccharide is selected from the group consisting of beta-D-galactose, glycoconjugates of beta-D-galactose, mannose, glycoconjugates of mannose, L-fucose, N-acetyl-glucosamine, N-acetylgalactosamine and N-acylneuraminic acid.
Claim 3
Dependent Claim 10 words
Method of claim 1, wherein the monosaccharide administration is β-D-galactose.
Claim 4
Dependent Claim 12 words
Method of claim 1, wherein the compound administered is a β-D-galactose glycoconjugate.
Claim 5
Dependent Claim 13 words
Method of claim 1, wherein the malignant tumors are color or liver tumors.

References Cited (Backward Citations)

US3931402A Cited
US4243663A Cited
US4389392A Cited
US4334017A Cited
US4316983A Cited
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US4742046A Cited
US4656159A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-08-06 1994-02-05 1994-08-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-08-06 1998-02-05 1998-08-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-08-06 2002-02-05 2002-08-07 $7700.00 Window Closed / Lapsed

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