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US4946450A Expired / Lapsed US ⏱️ 0.0 years remaining

Glucan/collagen therapeutic eye shields

Assignee: Large Scale Biology Corp
•
Filing: 1989-04-18
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Granted: 1990-08-07
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Expires: 2009-04-18
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Abstract

Abstract A therapeutic eye shield comprising from about 50% to about 80% collagen and from about 20% to about 50% glucan is disclosed. The collagen acts as a drug delivery system for the therapeutic agent, glucan. The therapeutic eye shields are useful for prophylaxis and treatment of eye infections particularly following ophthalmic surgery or wounding.

Inventors

  • 👤 Robert L. Erwin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 22:03
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K9/00; A61K9/0012; A61K9/0048; A61K9/0051

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 40 words
A therapeutic eye shield comprising a mixture of a therapeutically effective amount of glucan, and sufficient collagen to hold the glucan and form said therapeutic eye shield of sufficient dimensions to substantially cover a cornea when applied to an eye.
Claim 2
Dependent Claim 40 words
A therapeutic eye shield comprising a mixture of a therapeutically effective amount of glucan, and sufficient collagen to hold the glucan and form said therapeutic eye shield of sufficient dimensions to substantially cover a cornea when applied to an eye.
Claim 3
Dependent Claim 23 words
The therapeutic eye shield of claim 1 wherein said glucan is present from about 20% to about 50% by weight of said shield.
Claim 4
Dependent Claim 23 words
The therapeutic eye shield of claim 2 wherein said collagen is present from about 50% to about 80% by weight of said shield.
Claim 5
Dependent Claim 12 words
The therapeutic eye shield of claim 1 wherein said collagen is crosslinked.
Claim 6
Dependent Claim 12 words
The therapeutic eye shield of claim 3 wherein said collagen is crosslinked.
Claim 7
Dependent Claim 15 words
The therapeutic eye shield of claim 1 wherein said glucan is a water soluble glucan.
Claim 8
Dependent Claim 15 words
The therapeutic eye shield of claim 3 wherein said glucan is a water soluble glucan.
Claim 9
Dependent Claim 15 words
The therapeutic eye shield of claim 6 wherein said water soluble glucan is phosphorylated glucan.
Claim 10
Dependent Claim 15 words
The therapeutic eye shield of claim 7 wherein said water soluble glucan is phosphorylated glucan.
Claim 11
Dependent Claim 13 words
The therapeutic eye shield of claim 9 wherein said collagen is methylated collagen.
Claim 12
Dependent Claim 13 words
The therapeutic eye shield of claim 10 wherein said collagen is methylated collagen.
Claim 13
Dependent Claim 35 words
The therapeutic eye shield of claim 1 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 14
Dependent Claim 35 words
The therapeutic eye shield of claim 3 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 15
Dependent Claim 35 words
The therapeutic eye shield of claim 5 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 16
Dependent Claim 35 words
The therapeutic eye shield of claim 7 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 17
Dependent Claim 44 words
The therapeutic eye shield of claim 10 wherein said The therapeutic eye shield of claim 1 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 18
Dependent Claim 35 words
The therapeutic eye shield of claim 12 wherein said eye shield is substantially oval in shape, has a thickness from about 0.0125 millimeter to about 0.0725 millimeter and a base curve of about 9.0 millimeters.
Claim 19
Dependent Claim 19 words
A method of treating eye infections by applying the therapeutic eye shield of claim 1 to an infected eye.
Claim 20
Dependent Claim 29 words
A method of enhancing healing of an eye after surgery or wounding by applying the therapeutic eye shield of claim 1 to an eye after ophthalmic surgery or wounding.

References Cited (Backward Citations)

US3963025A Cited
US4164559A Cited
US4264155A Cited
US4739046A Cited
US4761402A Cited
US4833131A Cited
EP0214853A2 Cited
US4713446A Cited
JPS6371192A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-08-06 1994-02-05 1994-08-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-08-06 1998-02-05 1998-08-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-08-06 2002-02-05 2002-08-07 $7700.00 Window Closed / Lapsed

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