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US4942182A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment for cocaine addiction

Assignee: United States Department of Health and Human Services
•
Filing: 1989-03-01
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Granted: 1990-07-17
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Expires: 2009-03-01
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Abstract

Abstract Chronic oral adminstration of carbamazepine may be used to block reinforcing effects and toxic effects of cocaine. It is preferred that the subject be esstentially "clean" of codeine at the time the treatment with carbamazepine is commenced.

Inventors

  • 👤 Susan R. B. Weiss
  • 👤 Robert M. Post
  • 👤 Thomas G. Aigner

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 08:49
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/55; A61P; A61P25/00; A61P25/30

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 36 words
A method of blocking toxic effects of cocaine comprising the chronic administration of carbamazepine to a host susceptible to cocaine addiction in an amount sufficient to achieve a 4 0 12 ug/ml blood concentration of carbamazepine.
Claim 2
Independent Claim 36 words
A method of blocking toxic effects of cocaine comprising the chronic administration of carbamazepine to a host susceptible to cocaine addiction in an amount sufficient to achieve a 4 0 12 ug/ml blood concentration of carbamazepine.
Claim 3
Dependent Claim 11 words
A method of claim 1 wherein the carbamazepine is given orally.
Claim 4
Dependent Claim 14 words
A method of claim 2 wherein the dosage of carbamazepine given is 200-2000 mg/day.
Claim 5
Independent Claim 21 words
A method of blocking the reinforcing effects of cocaine by administering to a susceptible host a reinforcing-blocking effective amount of carbamazepine.
Claim 6
Independent Claim 21 words
A method of blocking the reinforcing effects of cocaine by administering to a susceptible host a reinforcing-blocking effective amount of carbamazepine.
Claim 7
Dependent Claim 18 words
A method of claim 4 wherein the carbamazepine is given by oral route in a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim 14 words
A method of claim 5 wherein the dosage of carbamazepine administered is 200-2000 mg/day.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-07-16 1994-01-15 1994-07-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-07-16 1998-01-15 1998-07-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-07-16 2002-01-15 2002-07-17 $7700.00 Window Closed / Lapsed

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