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US4940694A Expired / Lapsed US ⏱️ 0.0 years remaining

Therapeutic use of GM1 in severe cerebral ischemic strokes pathologies

Assignee: Fidia SpA
•
Filing: 1988-10-20
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Granted: 1990-07-10
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Expires: 2008-10-20
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Abstract

Abstract A pharmaceutical preparation containing the ganglio-side GM1 or an inner ester derivative thereof and a method for increasing cerebral blood flow in stroke victims by acute administration of GM1 or its inner ester derivative.

Inventors

  • 👤 Francesco Della Valle
  • 👤 Aurelio Romeo
  • 👤 Silvana Lorenzi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 02:44
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/02; C07H15/04; C07H15/10; A; A61; A61P; A61P25/00; A61P25/28; A61P9/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 35 words
A method for the treatment of cerebral stroke patients which comprises administering to said patients an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt of said ganglioside GM 1 .
Claim 2
Independent Claim 35 words
A method for the treatment of cerebral stroke patients which comprises administering to said patients an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt of said ganglioside GM 1 .
Claim 3
Independent Claim 36 words
A method for increasing cerebral blood flow and preventing neuronal death, which comprises administering an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt thereof to patients in need of such treatment.
Claim 4
Independent Claim 36 words
A method for increasing cerebral blood flow and preventing neuronal death, which comprises administering an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt thereof to patients in need of such treatment.
Claim 5
Independent Claim 41 words
A method for increasing cerebral blood flow in stroke patients and preventing neuronal death, without undesirably altering arterial blood pressure which comprises administering to said patients an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt thereof.
Claim 6
Independent Claim 41 words
A method for increasing cerebral blood flow in stroke patients and preventing neuronal death, without undesirably altering arterial blood pressure which comprises administering to said patients an effective amount of the ganglioside GM 1 , or a pharmaceutically acceptable salt thereof.
Claim 7
Dependent Claim 25 words
A method according to claim 1, wherein said ganglioside GM 1 is administered to said patient within seven days after the occurrence of a stroke.
Claim 8
Dependent Claim 25 words
A method according to claim 1, wherein said ganglioside GM 1 is administered to said patient within two days after the occurrence of a stroke.

References Cited (Backward Citations)

US4415733A Cited
US4435389A Cited
EP0072722A2 Cited
US4476119A Cited
US4521593A Cited
US4631294A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-07-09 1994-01-08 1994-07-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-07-09 1998-01-08 1998-07-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-07-09 2002-01-08 2002-07-10 $7700.00 Window Closed / Lapsed

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