US4936993A
Expired / Lapsed
US
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Apparatus for separation of blood components
Assignee: Terumo Corp
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Filing: 1987-06-29
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Granted: 1990-06-26
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Expires: 2007-06-29
Abstract
Abstract An apparatus for the separation of blood components, specifically for the removal of white blood cells and blood platelets from blood comprises a tubular housing providing at one end thereof with a blood inlet and at the other end thereof with a blood outlet and an aggregate layer of fibers capable of sequestering white blood cells and blood platelets packed in the housing. The aggregate layer of fibers comprises a blood inlet side layer of a bulk density of not less than 0.16 g/cm 3 and less than 0.21 g/cm 3 and a blood outlet side layer of a bulk density of not less than 0.21 g/cm 3 and not more than 0.23 g/cm 3 and is packed in a ratio in the range of 0.04 to 0.09 g per ml of the flow volume of blood under treatment.
Inventors
- 👤 Kazuhide Nomura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 12:49
CPC Classifications
B; B01; B01D; B01D39/00; B01D39/14; A; A61; A61M; A61M1/00; A61M1/36; A61M1/3621; A61M1/3627; A61M1/3633; B01D39/16; B01D39/1607; B01D39/1615; B01D39/1623; A61M2202/00; A61M2202/0042; A61M2202/005; A61M2202/04; A61M2202/0413; A61M2202/0429; A61M2202/0439; A61M2205/00; A61M2205/75; B01D2239/00; B01D2239/12; B01D2239/1291
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
237 words
An apparatus for separating white blood cells and blood platelets from blood, comprising: a tubular housing having at one end thereof a blood inlet and at another end thereof a blood outlet; a plurality of layers of staple fibers of bleached Egyptian cotton capable of sequestering white blood cells and blood platelets packed in said housing in the direction of flow of blood through said housing between said blood inlet and outlet; said layers of fibers comprising a blood inlet side fiber layer adjacent said blood inlet and a blood outlet side fiber layer adjacent said blood outlet, said blood inlet side fiber layer having a bulk density of not less than 0.16 g/cm 3 and not more than 0.21 g/cm 3 , and said blood outlet side fiber layer having a bulk density of not less than 0.21 g/cm 3 and not more than 0.23 g/cm 3 ; said plurality of layers of fibers being packed in a ratio in the range of 0.04 to 0.09 g per ml of the flow volume of blood under treatment by said apparatus; and wherein the ratio by weight of said blood inlet side fiber layer to said blood outlet side fiber layer is in the range of 75:25 to 60:40, and wherein the fibers of both said blood inlet side fiber layer and blood outlet side fiber layer are substantially the same except for their respective bulk densities.
Claim 2
Independent Claim
237 words
An apparatus for separating white blood cells and blood platelets from blood, comprising: a tubular housing having at one end thereof a blood inlet and at another end thereof a blood outlet; a plurality of layers of staple fibers of bleached Egyptian cotton capable of sequestering white blood cells and blood platelets packed in said housing in the direction of flow of blood through said housing between said blood inlet and outlet; said layers of fibers comprising a blood inlet side fiber layer adjacent said blood inlet and a blood outlet side fiber layer adjacent said blood outlet, said blood inlet side fiber layer having a bulk density of not less than 0.16 g/cm 3 and not more than 0.21 g/cm 3 , and said blood outlet side fiber layer having a bulk density of not less than 0.21 g/cm 3 and not more than 0.23 g/cm 3 ; said plurality of layers of fibers being packed in a ratio in the range of 0.04 to 0.09 g per ml of the flow volume of blood under treatment by said apparatus; and wherein the ratio by weight of said blood inlet side fiber layer to said blood outlet side fiber layer is in the range of 75:25 to 60:40, and wherein the fibers of both said blood inlet side fiber layer and blood outlet side fiber layer are substantially the same except for their respective bulk densities.
Claim 3
Dependent Claim
70 words
An apparatus according to claim 1, wherein said blood inlet side fiber layer comprises a first fiber layer of bulk density of not less than 0.16 g/cm 3 and not more than 0.19 g/cm 3 on the blood inlet side thereof, and a second fiber layer of a bulk density of not less than 0.19 g./cm 3 and not more than 0.21 g/cm 3 on the blood outlet side thereof.
Claim 4
Dependent Claim
36 words
An apparatus according to claim 2, wherein the ratio by weight of said first fiber layer to said second fiber layer of said blood inlet side fiber layer is in the range of 60:40 to 40:60.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-25 | 1993-12-25 | 1994-06-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-25 | 1997-12-25 | 1998-06-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-25 | 2001-12-25 | 2002-06-26 | $7700.00 | Window Closed / Lapsed |