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US4932964A Expired / Lapsed US ⏱️ 0.0 years remaining

Artificial body for a prosthesis

Assignee: IMS Biopur AG
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Filing: 1988-12-01
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Granted: 1990-06-12
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Expires: 2008-12-01
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Abstract

Abstract A prosthesis wall for an artificial organ, e.g. an artificial arterial blood vessel, to be coated without gaps on one side with biologically active epithelial, e.g. endothelial cells is provided with a structure of open continuous micropores a few microns in size. The pore size is limited to between 0.1 and 3 microns, at least on the surface to be coated with cells with the thickness of the partitions between the pores being not more than 3 microns to permit a continuous layer of endothelial cells with prolonged and firm adhesion to the prosthesis to be subsequently formed.

Inventors

  • 👤 Peter Bittmann
  • 👤 Peter Dittes
  • 👤 Werner Muller

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 17:47
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/062

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 76 words
An artificial body of bio-inert membrane-like plastic material, said body having a wall defining a surface and having a plurality of continuous open micropores at least partly communicating with each other and of a maximum linear dimension between 0.1 and 3 microns and a plurality of partitions between said micropores having a maximum width at said surface of not more than 3 microns whereby a continuous layer of epithelial cells can be coated on said surface.
Claim 2
Dependent Claim 76 words
An artificial body of bio-inert membrane-like plastic material, said body having a wall defining a surface and having a plurality of continuous open micropores at least partly communicating with each other and of a maximum linear dimension between 0.1 and 3 microns and a plurality of partitions between said micropores having a maximum width at said surface of not more than 3 microns whereby a continuous layer of epithelial cells can be coated on said surface.
Claim 3
Dependent Claim 25 words
An artificial body as set forth in claim 1 wherein said micropores extend in said wall over a depth of between 0.5 and 3 microns.
Claim 4
Dependent Claim 23 words
An artificial body as set forth in claim 2 wherein said micropores communicate with each other at least partly within said depth range.
Claim 5
Dependent Claim 61 words
An artificial arterial blood vessel comprising a wall defining an interior surface having a plurality of very fine micropores of a maximum linear dimension between 0.1 and 3 microns and a plurality of partitions between said micropores having a maximum width at said interior surface of not more than 3 microns for coating of a continuous layer of epithelial cells thereon.
Claim 6
Dependent Claim 61 words
An artificial arterial blood vessel comprising a wall defining an interior surface having a plurality of very fine micropores of a maximum linear dimension between 0.1 and 3 microns and a plurality of partitions between said micropores having a maximum width at said interior surface of not more than 3 microns for coating of a continuous layer of epithelial cells thereon.
Claim 7
Dependent Claim 19 words
An artificial arterial vessel as set forth in claim 4 having an internal diameter of seven millimeters or less.
Claim 8
Dependent Claim 25 words
An artificial arterial vessel as set forth in claim 5 wherein said very fine micropores extend over a depth of between 0.5 and 3 microns.
Claim 9
Dependent Claim 23 words
An artificial arterial vessel as set forth in claim 6 which further comprises a reinforcing material in said wall outside of said depth.
Claim 10
Dependent Claim 75 words
An artificial vessel comprising a tubular body of bio-inert membrane-like plastic material, said body having a wall defining an interior surface and having a plurality of very fine continuous open micropores of a diameter in the range of from 0.1 to 3 microns and a plurality of partitions between said micropores having a maximum width at said interior surface of not more than 3 microns for coating of a continuous layer of epithelial cells thereon.
Claim 11
Dependent Claim 75 words
An artificial vessel comprising a tubular body of bio-inert membrane-like plastic material, said body having a wall defining an interior surface and having a plurality of very fine continuous open micropores of a diameter in the range of from 0.1 to 3 microns and a plurality of partitions between said micropores having a maximum width at said interior surface of not more than 3 microns for coating of a continuous layer of epithelial cells thereon.
Claim 12
Dependent Claim 25 words
An artificial vessel as set forth in claim 8 wherein said micropores extend in said wall over a depth of between 0.5 and 3 microns.
Claim 13
Dependent Claim 23 words
An artificial vessel as set forth in claim 9 wherein said micropores communicate with each other at least partly within said depth range.
Claim 14
Dependent Claim 22 words
An artificial vessel as set forth in claim 8 which further comprises a reinforcing material in said wall outside of said depth.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-06-11 1993-12-11 1994-06-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-06-11 1997-12-11 1998-06-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-06-11 2001-12-11 2002-06-12 $7700.00 Window Closed / Lapsed

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