US4804382A
Expired / Lapsed
US
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Artificial vessel
Assignee: Sulzer AG
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Filing: 1987-05-19
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Granted: 1989-02-14
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Expires: 2007-05-19
Abstract
Abstract The artificial vessel has a membrane of at least semi-permeable bio-inert synthetic material with a monolayer of endothelial cells on the internal surface and a layer of smooth elastic fiber-generating muscle cells on the outer surface. The membrane may be made pore-less or may be made with a network of opened micropores filled with an aqueous gel to provide a smooth internal surface on which the endothelial cells may be coated.
Inventors
- 👤 Marko Turina
- 👤 Peter Bittmann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:07
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/507; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/062
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
48 words
An artificial vessel comprising a tubular membrane of at least semi-permeable bio-inert synthetic material; a monolayer of endothelial cells on an internal surface of said membrane for contact with a blood stream; and a layer of smooth elastic fiber-generating muscle cells on an outer surface of said membrane.
Claim 2
Dependent Claim
48 words
An artificial vessel comprising a tubular membrane of at least semi-permeable bio-inert synthetic material; a monolayer of endothelial cells on an internal surface of said membrane for contact with a blood stream; and a layer of smooth elastic fiber-generating muscle cells on an outer surface of said membrane.
Claim 3
Dependent Claim
21 words
An artificial vessel as set forth in claim 1 wherein said membrane is a poreless polymer of polyamino acids and urethane.
Claim 4
Dependent Claim
28 words
An artificial vessel as set forth in claim 1 wherein said membrane is a synthetic material with completely open micropores of a diameter between 10 and 50 μm.
Claim 5
Dependent Claim
18 words
An artificial vessel as set forth in claim 3 wherein said pores have a diameter of 30 μm.
Claim 6
Dependent Claim
24 words
An artificial vessel as set forth in claim 1 which further comprises a support structure surrounding said membrane to limit dilation of said membrane.
Claim 7
Dependent Claim
35 words
An artificial vessel as set forth in claim 5 wherein at an internal pressure of 80 to 150 mm Hg, said membrane has a linear elasticity of 0.03 to 0.1% per mm Hg pressure increase.
Claim 8
Dependent Claim
27 words
An artificial vessel as set forth in claim 5 wherein said support structure consists of a textile knitwear having a stitch width between 0.2 and 2 millimeters.
Claim 9
Dependent Claim
33 words
An artificial vessel as set forth in claim 7 wherein said support structure consists of braided material of individual spirally arranged filaments of polyester threads of a diameter of 10 to 40 μm.
Claim 10
Dependent Claim
21 words
An artificial vessael as set forth in claim 1 wherein said membrane has a thickness of from 0.1 to 1 millimeter.
Claim 11
Dependent Claim
69 words
An artificial vessel comprising a membrane of at least semi-permeable bio-inert synthetic material and having a thickness of from 0.1 to 1 millimeter; a monolayer of endothelial cells on an internal surface of said membrane for contact with a blood stream; a layer of smooth elastic fiber-generating muscle cells on an outer surface of said membrane; and a support structure surrounding said membrane to limit dilation of said membrane.
Claim 12
Dependent Claim
69 words
An artificial vessel comprising a membrane of at least semi-permeable bio-inert synthetic material and having a thickness of from 0.1 to 1 millimeter; a monolayer of endothelial cells on an internal surface of said membrane for contact with a blood stream; a layer of smooth elastic fiber-generating muscle cells on an outer surface of said membrane; and a support structure surrounding said membrane to limit dilation of said membrane.
Claim 13
Dependent Claim
33 words
An artificial vessel as set forth in claim 10 wherein said support structure consists of braided material of individual spirally arranged filaments of polyester threads of a diameter of 10 to 40 μm.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-02-14 | 1992-08-15 | 1993-02-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-02-14 | 1996-08-15 | 1997-02-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-02-14 | 2000-08-15 | 2001-02-14 | $7700.00 | Window Closed / Lapsed |