Patent US4929437A successfully refreshed from Google Patents.
US4929437A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Coenzyme Q10 with HMG-CoA reductase inhibitors
Assignee: Merck and Co Inc
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Filing: 1989-02-02
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Granted: 1990-05-29
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Expires: 2009-02-02
Abstract
Abstract A pharmaceutical composition and method of counteracting HMG-CoA reductase inhibitor-associated elevated transaminase levels is disclosed. The method comprises the adjunct administration of an effective amount of a HMG-CoA reductase inhibitor and an effective amount of Coenzyme Q 10 .
Inventors
- 👤 Jonathan A. Tobert
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:39
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/21; A61K31/215; A61K31/22
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
40 words
A method of counteracting HMG-CoA reductase inhibitor-associated elevated transaminase levels in a subject in need of such treatment which comprises the adjunct administration of an effective amount of HMG-CoA reductase inhibitor and an effective amount of Coenzyme Q 10 .
Claim 2
Independent Claim
40 words
A method of counteracting HMG-CoA reductase inhibitor-associated elevated transaminase levels in a subject in need of such treatment which comprises the adjunct administration of an effective amount of HMG-CoA reductase inhibitor and an effective amount of Coenzyme Q 10 .
Claim 3
Dependent Claim
23 words
A method of claim 1 in which the HMG-CoA reductase inhibitor is selected from the group consisting of: lovastatin, simvastatin, pravastatin and sodium-3,5-dihydroxy-7-[3-(4-fluorophenyl)-1-(methylethyl)-1H-indole-2-yl]-hept-6-enoate.
References Cited (Backward Citations)
US4654373A
Cited
US4713397A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-05-28 | 1993-11-27 | 1994-05-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-05-28 | 1997-11-27 | 1998-05-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-05-28 | 2001-11-27 | 2002-05-29 | $7700.00 | Window Closed / Lapsed |