US4925446A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Removable inflatable intragastrointestinal device for delivering beneficial agents
Assignee: Transpharm Group Inc
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Filing: 1988-07-06
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Granted: 1990-05-15
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Expires: 2008-07-06
Abstract
Abstract A removable inflatable beneficial agent delivery device that is adapted to reside in the stomach for a prolonged time period. The device comprises (1) an inflatable member which in its deflated state can be inserted into the stomach via a naso-gastric tube and which in its inflated state resides comfortably in the stomach but cannot pass through the pyloric sphincter, (2) an inflation tube connected to the inflatable member by which the inflatable member can be inflated from outside the body and which is dropped into the stomach after inflation, and (3) one or more agent-containing cartridges that are carried exteriorly on the inflatable member or the inflation tube and are capable of delivering agent to the gastrointestinal tract over a prolonged time period.
Inventors
- 👤 Garbiel L. Garay
- 👤 Kathleen M. K. Garay
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:19
CPC Classifications
A; A61; A61F; A61F5/00; A61F5/0003; A61F5/0013; A61F5/003; A61F5/0036; A61M; A61M25/00; A61M25/10; A61M25/1002; A61M37/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
170 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract.
Claim 2
Dependent Claim
170 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract.
Claim 3
Dependent Claim
12 words
The device of claim 1 wherein the beneficial agent is a drug.
Claim 4
Dependent Claim
207 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract, and (d) a magnetic body carried proximate to said other end of the inflation tube and providing a means by which the inflation tube may be magnetically retrieved from the stomach via the esophagus and mouth.
Claim 5
Dependent Claim
207 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract, and (d) a magnetic body carried proximate to said other end of the inflation tube and providing a means by which the inflation tube may be magnetically retrieved from the stomach via the esophagus and mouth.
Claim 6
Dependent Claim
184 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried on the exterior of the inflation tube, said cartidge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract and having an opening through it and being strung on the inflation tube via the opening.
Claim 7
Dependent Claim
184 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried on the exterior of the inflation tube, said cartidge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract and having an opening through it and being strung on the inflation tube via the opening.
Claim 8
Dependent Claim
31 words
The device of claim 4 wherein there is a plurality of cartridges, each of which has an opening through it, said cartridges being strung on the inflation tube via the openings.
Claim 9
Dependent Claim
180 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state said inflatable member having an opening in it that defines a cavity; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried in the cavity of the inflatable member, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract.
Claim 10
Dependent Claim
180 words
A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising: (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state said inflatable member having an opening in it that defines a cavity; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried in the cavity of the inflatable member, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract.
Claim 11
Dependent Claim
16 words
The device of claim 6 wherein the ends of the opening are closed by perforated members.
Claim 12
Dependent Claim
19 words
The device of claim 6 wherein there is a plurality of cartridges each of which resides in the cavity.
Claim 13
Dependent Claim
17 words
The device of claim 1 wherein the inflatable member has a toroidal shape in its inflated state.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-05-14 | 1993-11-13 | 1994-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-05-14 | 1997-11-13 | 1998-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-05-14 | 2001-11-13 | 2002-05-15 | $7700.00 | Window Closed / Lapsed |