Apparatus for making mixtures of pharmaceutical liquids

Claim 1

Apparatus for making a mixture of pharmaceutical liquids in a container, the individual liquid components of the mixture being contained in at least first and second supply vessels, said apparatus comprising: a connection tube for each supply vessel; a tube connector means connected with said connection tubes; a further tube for connecting said tube connector means to the container to be filled with the mixture; a vacuum chamber for containing the container to be filled; a vacuum pump connected to said vacuum chamber; first and second shut off means for said connection tubes of the at least first and second supply vessels, respectively; means for detecting the presence of air in the apparatus; pressure sensor means for detecting negative pressure values within said vacuum chamber; an input device for storing values of volumes of liquid components of the mixture to be transferred from the at least first and second supply vessels to the container; and control means operatively connected with said pressure sensor means, said vacuum pump, and said first and second shut off means, said control means activating said vacuum pump until a first predetermined negative pressure value is obtained in said vacuum chamber, thereafter opening said first shut off means for allowing liquid to flow from the first supply vessel to the container until a second predetermined pressure exists in said chamber, and thereafter closing said first shut off means and opening said second shut off means for allowing liquid to flow from the second supply vessel to the container until a third predetermined pressure value exists in said chamber.