Patent US4919891A successfully refreshed from Google Patents.
US4919891A
Expired / Lapsed
US
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Sensor with overcoating and process for making same
Assignee: 3M Co
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Filing: 1987-05-15
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Granted: 1990-04-24
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Expires: 2007-05-15
Abstract
Abstract A sensor comprising a sensing element capable of sensing a component in an aqueous medium and an overcoating at least partially covering the sensing element. The overcoating comprises a water insoluble, component permeable, cross-linked cellulosic material and an effective amount of an opaque agent.
Inventors
- 👤 Masao Yafuso
- 👤 Henry K. Hui
- 👤 Cheng F. Yan
- 👤 William W. Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:06
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/62; G01N21/63; G01N21/64; G01N21/6428; G01N21/643; A; A61; A61B; A61B5/00; A61B5/145; A61B5/1455; A61B5/1459; G01N31/00; G01N31/22; G01N31/223; G01N2021/6434; G01N2021/6439; G01N21/75; G01N21/77; G01N21/78; G01N21/80; G01N21/81
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
51 words
A sensor comprising a sensing element capable of sensing a component in an aqueous medium and an overcoating at least partially covering said sensing element, said overcoating comprising a water insoluble, component permeable cellulosic material cross-linked with one or more multi-functional cross-linking agents and an effective amount of an opaque agent.
Claim 2
Dependent Claim
51 words
A sensor comprising a sensing element capable of sensing a component in an aqueous medium and an overcoating at least partially covering said sensing element, said overcoating comprising a water insoluble, component permeable cellulosic material cross-linked with one or more multi-functional cross-linking agents and an effective amount of an opaque agent.
Claim 3
Dependent Claim
21 words
The sensor of claim 1 wherein said sensing element is selected from the group consisting of optical indicators and electro-chemical indicators.
Claim 4
Dependent Claim
18 words
The sensor of claim 1 wherein, said sensing element is selected from the group consisting of optical indicators.
Claim 5
Dependent Claim
21 words
The sensor of claim 1 wherein said sensing element is selected from the group consisting of fluorescence indicators and absorbance indicators.
Claim 6
Dependent Claim
18 words
The sensor of claim 1 wherein said sensing element is selected from the group consisting of fluorescence indicators.
Claim 7
Dependent Claim
15 words
The sensor of claim 5 wherein said opaque agent is a dye adsorptive opaque agent.
Claim 8
Dependent Claim
24 words
The sensor of claim 6 wherein said opaque agent is a dye adsorptive opaque agent and said dye adsorptive opaque agent is carbon black.
Claim 9
Dependent Claim
18 words
The sensor of claim 6 wherein said sensing element is a fluorescence indicator capable of sensing carbon dioxide.
Claim 10
Dependent Claim
15 words
The sensor of claim 5, wherein said opaque agent is a dye non-adsorptive opaque agent.
Claim 11
Dependent Claim
23 words
The sensor of claim 9 wherein said dye non-adsorptive opaque agent is selected from the group consisting of ferric oxide and metallic phthalocyanines.
Claim 12
Dependent Claim
42 words
The sensor of claim 10 wherein said dye non-adsorptive opaque agent is a metallic phthalocyanine and the metallic portion of said phthalocyanine is selected from the group consisting of copper, iron, cobalt, lithium, magnesium, nickel, zinc, vanadium, manganese, sodium and mixtures thereof.
Claim 13
Dependent Claim
17 words
The sensor of claim 9 wherein said sensing element is a fluorescence indicator capable of sensing oxygen.
Claim 14
Dependent Claim
14 words
The sensor of claim 12 wherein said dye non-adsorptive opaque agent is copper phthalocyanine.
Claim 15
Dependent Claim
13 words
The sensor of claim 1 wherein said aqueous medium is a bodily fluid.
Claim 16
Dependent Claim
20 words
The sensor of claim 14 which further comprises a blood compatible film located on the outside surface of said overcoating.
Claim 17
Dependent Claim
11 words
The sensor of claim 1 wherein said aqueous medium is blood.
Claim 18
Dependent Claim
13 words
The sensor of claim 1 wherein said cross-linked cellulosic material is cross-linked cellulose.
Claim 19
Dependent Claim
22 words
The sensor of claim 1 wherein said component is selected from the group consisting of gases, hydrogen ions, other electrolytes and glucose.
Claim 20
Dependent Claim
19 words
The sensor of claim 1 wherein said component is selected from the group consisting of gases and hydrogen ions.
Claim 21
Dependent Claim
21 words
The sensor of claim 1 wherein said component is selected from the group consisting of oxygen, carbon dioxide and hydrogen ions.
Claim 22
Dependent Claim
91 words
An overcoated sensing element produced in accordance with the process comprising: contacting a sensing element with a composition containing a solvent and a solvent soluble cellulosic coating material or a solvent soluble precursor of said cellulosic coating material to form a composition coated sensing element; and treating said composition coated sensing element to form an overcoating on said sensing element, said overcoating being permeable to a component of interest, wherein said composition further includes a permeability enhancing agent in an amount effective to enhance the component permeability of said overcoating formed.
Claim 23
Dependent Claim
91 words
An overcoated sensing element produced in accordance with the process comprising: contacting a sensing element with a composition containing a solvent and a solvent soluble cellulosic coating material or a solvent soluble precursor of said cellulosic coating material to form a composition coated sensing element; and treating said composition coated sensing element to form an overcoating on said sensing element, said overcoating being permeable to a component of interest, wherein said composition further includes a permeability enhancing agent in an amount effective to enhance the component permeability of said overcoating formed.
Claim 24
Dependent Claim
27 words
An overcoated sensing element as defined in claim 21 wherein said permeability enhancing agent is substantially removed from said composition coated sensing element during said treating step.
Claim 25
Dependent Claim
65 words
An overcoated sensing element as defined in claim 22 wherein said permeability enhancing agent is water soluble and said treating step comprises contacting said composition coated sensing element at conditions effective to form a cross-linked cellulosic material on said sensing element and contacting said sensing element containing said cross-linked cellulosic material with an aqueous liquid at conditions effective to substantially remove said permeability enhancing agent.
Claim 26
Dependent Claim
64 words
An overcoated sensing element as defined in claim 23 wherein said composition coated sensing element is contacted at conditions effective to hydrolyze at least a portion of said cellulosic material on said sensing element, and said sensing element containing said hydrolyzed cellulosic material is contacted with at least one cross-linking agent at conditions effective to form a cross-linked cellulosic material on said sensing element.
Claim 27
Dependent Claim
114 words
A probe capable of sensing a plurality of different components in an aqueous medium which comprises: a plurality of sensing elements each of which is capable of sensing a different one of said components in said aqueous medium; a plurality of first overcoatings each of which is located on a different one of said sensing elements and each of which comprises a water insoluble, component permeable cellulosic material cross-linked with one or more multi-functional cross-linking agents and an effective amount of first opaque agent; and a second overcoating located on all said first overcoated sensing elements and comprising a water insoluble, all component permeable cellulosic material cross-linked with one or more multi-functional across-linking agents.
Claim 28
Dependent Claim
114 words
A probe capable of sensing a plurality of different components in an aqueous medium which comprises: a plurality of sensing elements each of which is capable of sensing a different one of said components in said aqueous medium; a plurality of first overcoatings each of which is located on a different one of said sensing elements and each of which comprises a water insoluble, component permeable cellulosic material cross-linked with one or more multi-functional cross-linking agents and an effective amount of first opaque agent; and a second overcoating located on all said first overcoated sensing elements and comprising a water insoluble, all component permeable cellulosic material cross-linked with one or more multi-functional across-linking agents.
Claim 29
Dependent Claim
21 words
The probe of claim 25 wherein said sensing elements are selected from the group consisting of optical indicators and electro-chemical indicators.
Claim 30
Dependent Claim
13 words
The probe of claim 26 wherein said aqueous medium is a bodily fluid.
Claim 31
Dependent Claim
18 words
The probe of claim 25 wherein said sensing elements are selected from the group consisting of optical indicators.
Claim 32
Dependent Claim
21 words
The probe of claim 25 wherein said sensing elements are selected from the group consisting of fluorescence indicators and absorbance indicators.
Claim 33
Dependent Claim
18 words
The probe of claim 25 wherein said sensing elements are selected from the group consisting of fluorescence indicators.
Claim 34
Dependent Claim
18 words
The probe of claim 30 wherein each of said first opaque agents is a dye adsorptive opaque agent.
Claim 35
Dependent Claim
31 words
The probe of claim 31 wherein said second overcoating further comprises an effective amount of a second opaque agent and wherein said second opaque agent is a dye non-adsorptive opaque agent.
Claim 36
Dependent Claim
23 words
The probe of claim 32 wherein said dye adsorptive opaque agent is carbon black and said dye non-adsorptive opaque agent is copper phthalocyanine.
Claim 37
Dependent Claim
18 words
The probe of claim 30 wherein each of said first opaque agents is a dye non-adsorptive opaque agent.
Claim 38
Dependent Claim
19 words
The probe of claim 25 wherein said second overcoating further comprises an effective amount of a second opaque agent.
Claim 39
Dependent Claim
11 words
The probe of claim 25 wherein said aqueous medium is blood.
Claim 40
Dependent Claim
13 words
The probe of claim 25 wherein said cross-linked cellulosic material is cross-linked cellulose.
Claim 41
Dependent Claim
22 words
The probe of claim 25 wherein said components are selected from the group consisting of gases, hydrogen ions, other electrolytes and glucose.
Claim 42
Dependent Claim
25 words
The probe of claim 25 wherein said aqueous medium is blood and said probe further comprises a blood compatible film located on said second overcoating.
References Cited (Backward Citations)
US4682895A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-04-23 | 1993-10-23 | 1994-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-04-23 | 1997-10-23 | 1998-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-04-23 | 2001-10-23 | 2002-04-24 | $7700.00 | Window Closed / Lapsed |