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US4906374A Expired / Lapsed US ⏱️ 0.0 years remaining

Filtration media with low protein adsorbability

Assignee: Pall Corp
•
Filing: 1986-12-23
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Granted: 1990-03-06
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Expires: 2006-12-23
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Abstract

Abstract A porous polymeric medium having a low affinity for amide group-containing materials is provided comprising a porous polymeric substrate and a surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded to the surface of the porous polymeric substrate, the surface-modifying polymeric material being formed from a monofunctional monomer having at least one hydroxyl group.

Inventors

  • 👤 Thomas C. Gsell

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 11:56
CPC Classifications
B; B01; B01D; B01D69/00; B01D69/12; B01D39/00; B01D39/14; B01D39/16; B01D67/00; B01D67/0081; B01D67/0093; B01D67/00931; C; C08; C08J; C08J9/00; C08J9/36; C08J9/40; C08J9/405; B01D2323/00; B01D2323/38; Y; Y10; Y10T; Y10T428/00; Y10T428/249921; Y10T428/249953; Y10T428/249978; Y10T428/249979; Y10T428/31504; Y10T428/31725; Y10T428/31739

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 63 words
A porous polymeric medium having a low affinity for amide-group containing materials comprising: a porous polymeric substrate; and a surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded directly to the surface of said porous polymeric substrate, said surface-modifying polymeric material being derived from an unsaturated monofunctional misnomer having at least one hydroxyl group.
Claim 2
Dependent Claim 63 words
A porous polymeric medium having a low affinity for amide-group containing materials comprising: a porous polymeric substrate; and a surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded directly to the surface of said porous polymeric substrate, said surface-modifying polymeric material being derived from an unsaturated monofunctional misnomer having at least one hydroxyl group.
Claim 3
Dependent Claim 27 words
The porous polymeric medium of claim 1 wherein said polymeric substrate comprises a material having C-H bonds capable of forming radicals under the influence of ionizing radiation.
Claim 4
Dependent Claim 15 words
The porous polymeric medium of claim 1 wherein said porous polymeric substrate comprises a polyamide.
Claim 5
Dependent Claim 13 words
The porous polymeric medium of claim 3 wherein said polyamide is nylon 66.
Claim 6
Dependent Claim 16 words
The porous polymeric medium of claim 1 wherein said porous polymeric substtrate comprises a hydrophilic material.
Claim 7
Dependent Claim 19 words
The porous polymeric medium of claim 1 wherein said polymeric material comprises a material rich in pendant hydroxyl groups.
Claim 8
Dependent Claim 14 words
The porous polymeric medium of claim 1 wherein said porous polymeric substrate is microporous.
Claim 9
Dependent Claim 17 words
The porous polymeric medium of claim 1 wherein said porous polymeric substrate and said medium are microporous.
Claim 10
Dependent Claim 23 words
The porous polymeric medium of claim 1 wherein said monomer from which said surface-modifying polymeric material is formed comprises an ethylenically unsaturated compound.
Claim 11
Dependent Claim 17 words
The porous polymeric medium according to claim 9 wherein said monomer is an hydroxyalkyl acrylate or methacrylate.
Claim 12
Dependent Claim 18 words
The porous polymeric medium according to claim 10 wherein the hyroxyalkyl group contains 2 to 5 carbon atoms.
Claim 13
Dependent Claim 26 words
The porous polymeric medium according to claim 9 wherein said monomer is 2-hydroxypropyl arylate, 2-hydroxypropyl metharylate, 3-hydroxypropyl acrylate, 3-hydroxypropyl methacrylate, or mixtures of the foregoing monomers.
Claim 14
Dependent Claim 15 words
The porous polymeric medium of claim 1 wherein said amide group-containing material comprises proteinaceous material.
Claim 15
Dependent Claim 32 words
The porous polymeric medium of claim 13 wherein said medium has an adsorption of proteinaceous material measured by the Bovine Serum Albumin Adsorption Test of less than 100 micrograms per square centimeter.
Claim 16
Dependent Claim 35 words
The porous polymeric medium according to claim 1 wherein said monomer is a monomer capable of polymerizing and forming a polymer and covalently bonding to said porous polymeric substrate under the influence of ionizing radiation.
Claim 17
Dependent Claim 70 words
A porous polymeric medium having a low affinity for amide group-containing materials comprising: a porous polymeric substrate; and a hydroxyl-containing surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded directly to the surface of said porous polymeric substrate, said surface-modifying polymeric material being derived from an unsaturated monofunctional monomer having at least one hydroxyl group or group capable of forming same.
Claim 18
Dependent Claim 70 words
A porous polymeric medium having a low affinity for amide group-containing materials comprising: a porous polymeric substrate; and a hydroxyl-containing surface-modifying polymeric material having a low affinity for amide group-containing materials formed in situ at and covalently bonded directly to the surface of said porous polymeric substrate, said surface-modifying polymeric material being derived from an unsaturated monofunctional monomer having at least one hydroxyl group or group capable of forming same.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-03-05 1993-09-04 1994-03-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-03-05 1997-09-04 1998-03-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-03-05 2001-09-04 2002-03-06 $7700.00 Window Closed / Lapsed

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