EP0091128A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Synthetic wound covering
Assignee: Israel Atomic Energy Commission
•
Filing: 1983-04-06
•
Granted: —
•
Expires: 2003-04-06
Abstract
Abstract A synthetic wound covering consisting of a thin, tough, elastic hydrophilic membrane whose thickness does not exceed 60µ, having a water permeability of 2,400-8,000 g/m<sup>2</sup>/24h at 37°C and 60% relative humidity being a product obtained by grafting a hydrophilic monomer to a thin body of polyurethane.One group of polyurethanes suitable for making the artificial skin is characterised by a recurring unit of the formulain which R<sub>1</sub> and R<sub>2</sub> are each a group -(CH<sub>2</sub>)<sub>x</sub>- where x is an integer of 1 to 8 and the average value of n is 2.5 to 20.
Inventors
- 👤 David Behar
- 👤 Marta Juszynski
- 👤 Arie L. Rajbenbach
- 👤 Nahum Ben-Hur
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-30 07:56
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/22; A61L15/26
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
48 words
A synthetic wound covering consisting of a thin, tough, elastic hydrophilic membrane whose thickness does not exceed 60µ, having a water permeability of 2,400-8,000 g/m 2 /24h at 37°C and 60% relative humidity being a product obtained by grafting a hydrophilic monomer to a thin body of polyurethane.
Claim 2
Dependent Claim
48 words
A synthetic wound covering consisting of a thin, tough, elastic hydrophilic membrane whose thickness does not exceed 60µ, having a water permeability of 2,400-8,000 g/m 2 /24h at 37°C and 60% relative humidity being a product obtained by grafting a hydrophilic monomer to a thin body of polyurethane.
Claim 3
Dependent Claim
24 words
An artificial skin according to claim 1, wherein the polyurethane has a module of elasticity below 1500 PSI, and elongation at break above 500%.
Claim 4
Dependent Claim
76 words
An artificial skin according to claim 1 or 2, wherein the polyurethane is a polyester polyurethane having a recurring unit of the formula -[(OR 1 OCOR 2 CO) n OR 1 OCONH-C 6 H 4 CH 2 C 6 H 4 -NHCO]-in which R 1 and R 2 are each a group -(CH 2 ) x - where x is an integer of 1 to 8, and n has an average value of 2.5 to 20.
Claim 5
Dependent Claim
15 words
An artificial skin according to claim 3, wherein average n is from 2.5 to 8.
Claim 6
Dependent Claim
26 words
An artificial skin according to claim 3 or 4, wherein R 1 and R 2 are each a tetra methylene group -(CH 2 ) 4 -.
Claim 7
Dependent Claim
21 words
An artificial skin according to any one of claims 1 to 5, wherein the hydrophilic monomer is a vinyl type monomer.
Claim 8
Dependent Claim
13 words
An artificial skin according to claim 6, wherein the hydrophilic monomer is acrylamide.
Claim 9
Dependent Claim
14 words
An artificial skin according to claim 6, wherein the hydrophilic monomer is hydroxyethyl acrylate.
Claim 10
Dependent Claim
14 words
An artificial skin according to claim 6, wherein the hydrophilic monomer is acrylic acid.
Claim 11
Dependent Claim
14 words
An artificial skin according to claim 6, wherein the hydrophilic monomer is hydroxyethyl methacrylate.
Claim 12
Dependent Claim
19 words
An artificial skin according to any one of claims 1 to 10 whose thickness is not less than 10u.
Claim 13
Dependent Claim
20 words
An artificial skin according to any one of claims 1 to 11 whose physical properties are affected by water absorption.
Claim 14
Dependent Claim
22 words
An artificial skin according to any one of claims 1 to 12 adapted to peel off from the healed wound when dry.
Claim 15
Independent Claim
100 words
A method of making an artificial skin according to any one of claims 1 to 13 comprising preparing an aqueous solution of hydrophilic monomer and a salt of a transition metal whose ion is capable of serving as inhibitor for homopolymerization of the monomer, immersing into such a solution a film of a polyurethane as defined in any one of claims 1 to 5 and whose thickness does not exceed 60p, subjecting the solution with the film in it to conditions inducive of radical graft copolymerization and continuing the reaction until a product of the desired water permeability is obtained.
Claim 16
Dependent Claim
23 words
A process according to claim 14, wherein the induction of radical graft polymerization is effected by means of irradiation with an ionizing irradiation.
Claim 17
Dependent Claim
18 words
A process according to claim 15, wherein 60 C o is used as a source of said radiation.
Claim 18
Dependent Claim
18 words
A process according to any one of claims 14 to 16, wherein the inhibitor is Ce 4+ salt.
Claim 19
Dependent Claim
30 words
A process according to claim 14, wherein the induction of radical graft copolymerization and simultaneous inhibition of homopolymerization is effected by the incorporation in solution of a Ce 4+ salt.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.