Patent US4904469A successfully refreshed from Google Patents.
US4904469A
Expired / Lapsed
US
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Therapeutic agents for enzymatic wound cleaning
Assignee: Roehm GmbH Darmstadt
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Filing: 1987-02-05
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Granted: 1990-02-27
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Expires: 2007-02-05
Abstract
Abstract The invention relates to a wound covering made from a polysaccharide base, particularly cellulose, which is formed as a fabric, which has a high absorbency due to its sponge-like structure and contains non-immobilized enzymes for wound therapy.
Inventors
- 👤 Hans-Ulrich Petereit
- 👤 Gerhard Zeiss
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 10:29
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/425; A61L15/22; A61L15/28; A61L15/38
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
59 words
A wound covering for topical skin treatment, consisting essentially of (i) a sponge-like carrier consisting essentially of cellulose polysaccharide, and (ii) an enzymatically effective amount of at least one enzyme in contact with said polysaccharide, wherein said wound covering has an absorbency of 1,500 to 3,000% by weight of water, relative to the dry mass of said cellulose polysaccharide.
Claim 2
Dependent Claim
59 words
A wound covering for topical skin treatment, consisting essentially of (i) a sponge-like carrier consisting essentially of cellulose polysaccharide, and (ii) an enzymatically effective amount of at least one enzyme in contact with said polysaccharide, wherein said wound covering has an absorbency of 1,500 to 3,000% by weight of water, relative to the dry mass of said cellulose polysaccharide.
Claim 3
Dependent Claim
25 words
The wound covering of claim 1, wherein said enzyme is a member selected from the group consisting of proteases, ribonucleases, deoxyribonucleases, hyaluronidases and mixtures thereof.
Claim 4
Dependent Claim
12 words
The wound covering of claim 2, wherein said enzyme is a protease.
Claim 5
Dependent Claim
15 words
The wound covering of claim 2, wherein said enzyme is a ribonuclease or a deoxyribonuclease.
Claim 6
Dependent Claim
21 words
The wound covering of claim 1, further consisting essentially of therapeutic ingredients selected from the group consisting of pharmaceuticals and salves.
Claim 7
Dependent Claim
24 words
The wound covering of claim 5, wherein said therapeutic ingredient is a pharmaceutical selected from the group consisting of antibiotics, hormones and their derivatives.
Claim 8
Dependent Claim
12 words
The wound covering of claim 2, wherein said enzyme is a hyaluronidase.
Claim 9
Dependent Claim
19 words
The wound covering of claim 1, wherein said sponge-like polysaccharide is in a form comprising at least one layer.
Claim 10
Dependent Claim
19 words
The wound covering of claim 8, wherein said layer or layers are from about 0.1 to 10 mm thick.
Claim 11
Dependent Claim
26 words
The wound covering of claim 1, wherein said wound covering has an enzyme activity of between about 2.0 and 4.0 protease units per cm 2 (FIP).
Claim 12
Dependent Claim
25 words
The wound covering of claim 10, wherein said wound covering has an enzymatic activity between about 2.9 and 3.2 protease units per cm 2 (FIP).
Claim 13
Dependent Claim
22 words
The wound covering of claim 1, wherein said wound covering has a proteolytic activity between about 10-500 PE per cm 2 .
Claim 14
Dependent Claim
22 words
The wound covering of claim 12, wherein said wound covering has a proteolytic activity between about 50-250 PE per cm 2 .
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-02-26 | 1993-08-28 | 1994-02-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-02-26 | 1997-08-28 | 1998-02-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-02-26 | 2001-08-28 | 2002-02-27 | $7700.00 | Window Closed / Lapsed |