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US4897259A
Expired / Lapsed
US
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High oil phase pharmaceutical vehicles and sunscreen compositions having waterproof sun protection factors
Assignee: CUTIX INC
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Filing: 1988-11-07
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Granted: 1990-01-30
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Expires: 2008-11-07
Abstract
Abstract High oil phase pharmaceutical vehicles in the form of an emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises from about 1% to about 13% of an alkylated PVP copolymer, from about 1% to about 7% of an emulsifier, and a solvent system. The solvent system comprises from about 4% to about 18% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 2% to about 25% of a glycol ester or diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid. The pharmaceutical vehicles are useful in sunscreen formulations, and especially those containing higher concentrations of benzophenone-3. When such higher concentrations are used, it is advantageous to add up to about 10% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Inventors
- 👤 Terrence J. Murray
- 👤 Bhiku G. Patel
- 👤 Richard O. Muhlhauser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 17:57
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/375; A61K8/02; A61K8/04; A61K8/06; A61K8/35; A61K8/40; A61K8/44; A61K8/445; A61K8/55; A61K8/72; A61K8/81; A61K8/817; A61K8/8182; A61Q; A61Q17/00; A61Q17/04
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
110 words
A waterproof pharmaceutical vehicle in the form of an aqueous emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises: from about 1% to about 10% of an oil soluble polyvinylpyrrolidone and long alkyl chain olefin copolymer; from about 2% to about 10% of an emulsifier; and a solvent system comprising from about 4% to about 20% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 4% to about 25% of a glycol ester or glycol diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Claim 2
Dependent Claim
110 words
A waterproof pharmaceutical vehicle in the form of an aqueous emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises: from about 1% to about 10% of an oil soluble polyvinylpyrrolidone and long alkyl chain olefin copolymer; from about 2% to about 10% of an emulsifier; and a solvent system comprising from about 4% to about 20% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 4% to about 25% of a glycol ester or glycol diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Claim 3
Dependent Claim
23 words
The pharmaceutical vehicle of claim 1 wherein the copolymer comprises a copalymer of polyvinylpyrrolidone and hexadecene or a copolymer of polyvinylpyrrolidone and licosene.
Claim 4
Dependent Claim
21 words
The pharmaceutical vehicle of claim 2 wherein the copolymer is present in an amount of from about 2.5% to about 7.5%.
Claim 5
Dependent Claim
16 words
The pharmaceutical vehicle of claim 3 wherein the emulsifier comprises cetyl phosphate and DEA cetyl phosphate.
Claim 6
Dependent Claim
20 words
The pharmaceutical vehicle of claim 4 wherein the emulsifier is present in an amount of from about 2% to 5%.
Claim 7
Dependent Claim
31 words
The pharmaceutical vehicle of claim 2 wherein the solvent system comprises from about 6% to about 15% of isopropyl myristate and from about 4% to about 20% of propylene glycol dioctanoate.
Claim 8
Dependent Claim
17 words
The pharmaceutical vehicle of claim 6 comprising additionally from about 3% to about 13% of isodecyl neopentanoate.
Claim 9
Dependent Claim
16 words
The pharmaceutical vehicle of claim 6 wherein the copolymer comprises a copolymer of polyvinylpyrrolidone and licosene.
Claim 10
Dependent Claim
16 words
The pharmaceutical vehicle of claim 7 wherein the copolymer comprises a copolymer of polyvinylpyrrolidone and licosene.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-29 | 1993-07-31 | 1994-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-29 | 1997-07-31 | 1998-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-29 | 2001-07-31 | 2002-01-30 | $7700.00 | Window Closed / Lapsed |