US4897259A
Expired / Lapsed
US
⏱️ 0.0 years remaining
High oil phase pharmaceutical vehicles and sunscreen compositions having waterproof sun protection factors
Assignee: CUTIX INC
•
Filing: 1988-11-07
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Granted: 1990-01-30
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Expires: 2008-11-07
Abstract
Abstract High oil phase pharmaceutical vehicles in the form of an emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises from about 1% to about 13% of an alkylated PVP copolymer, from about 1% to about 7% of an emulsifier, and a solvent system. The solvent system comprises from about 4% to about 18% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 2% to about 25% of a glycol ester or diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid. The pharmaceutical vehicles are useful in sunscreen formulations, and especially those containing higher concentrations of benzophenone-3. When such higher concentrations are used, it is advantageous to add up to about 10% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Inventors
- 👤 Terrence J. Murray
- 👤 Bhiku G. Patel
- 👤 Richard O. Muhlhauser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 10:10
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/375; A61K8/02; A61K8/04; A61K8/06; A61K8/35; A61K8/40; A61K8/44; A61K8/445; A61K8/55; A61K8/72; A61K8/81; A61K8/817; A61K8/8182; A61Q; A61Q17/00; A61Q17/04
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
110 words
A waterproof pharmaceutical vehicle in the form of an aqueous emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises: from about 1% to about 10% of an oil soluble polyvinylpyrrolidone and long alkyl chain olefin copolymer; from about 2% to about 10% of an emulsifier; and a solvent system comprising from about 4% to about 20% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 4% to about 25% of a glycol ester or glycol diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Claim 2
Dependent Claim
110 words
A waterproof pharmaceutical vehicle in the form of an aqueous emulsion system having an oil phase content of from about 35% to about 65%, wherein the emulsion system comprises: from about 1% to about 10% of an oil soluble polyvinylpyrrolidone and long alkyl chain olefin copolymer; from about 2% to about 10% of an emulsifier; and a solvent system comprising from about 4% to about 20% of a C 4 -C 22 fatty acid, alcohol or ester thereof, from about 4% to about 25% of a glycol ester or glycol diester, and from 0% to about 13% of a branched chain ester of a C 4 -C 22 carboxylic acid.
Claim 3
Dependent Claim
23 words
The pharmaceutical vehicle of claim 1 wherein the copolymer comprises a copalymer of polyvinylpyrrolidone and hexadecene or a copolymer of polyvinylpyrrolidone and licosene.
Claim 4
Dependent Claim
21 words
The pharmaceutical vehicle of claim 2 wherein the copolymer is present in an amount of from about 2.5% to about 7.5%.
Claim 5
Dependent Claim
16 words
The pharmaceutical vehicle of claim 3 wherein the emulsifier comprises cetyl phosphate and DEA cetyl phosphate.
Claim 6
Dependent Claim
20 words
The pharmaceutical vehicle of claim 4 wherein the emulsifier is present in an amount of from about 2% to 5%.
Claim 7
Dependent Claim
31 words
The pharmaceutical vehicle of claim 2 wherein the solvent system comprises from about 6% to about 15% of isopropyl myristate and from about 4% to about 20% of propylene glycol dioctanoate.
Claim 8
Dependent Claim
17 words
The pharmaceutical vehicle of claim 6 comprising additionally from about 3% to about 13% of isodecyl neopentanoate.
Claim 9
Dependent Claim
16 words
The pharmaceutical vehicle of claim 6 wherein the copolymer comprises a copolymer of polyvinylpyrrolidone and licosene.
Claim 10
Dependent Claim
16 words
The pharmaceutical vehicle of claim 7 wherein the copolymer comprises a copolymer of polyvinylpyrrolidone and licosene.
References Cited (Backward Citations)
US3529055A
Cited
US3821363A
Cited
US3784488A
Cited
US3743715A
Cited
US3728319A
Cited
US3670074A
Cited
US3864473A
Cited
US3895104A
Cited
US4426374A
Cited
US4128633A
Cited
US4172122A
Cited
US4241048A
Cited
CA1196868A
Cited
CA1196577A
Cited
US4597963A
Cited
EP0193387A2
Cited
US4567038A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-29 | 1993-07-31 | 1994-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-29 | 1997-07-31 | 1998-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-29 | 2001-07-31 | 2002-01-30 | $7700.00 | Window Closed / Lapsed |