US4897185A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cell processing apparatus and method
Assignee: Terumo BCT Inc
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Filing: 1988-10-06
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Granted: 1990-01-30
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Expires: 2008-10-06
Abstract
Abstract Using a membrane separating device to remove cell-free fluid from a suspension of cells to preconcentrate cells in the suspension prior to processing in a centrifuge.
Inventors
- 👤 Robert J. Schuyler
- 👤 Robert L. White
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:44
CPC Classifications
B; B01; B01D; B01D61/00; B01D61/14; B01D61/147; A; A61; A61M; A61M1/00; A61M1/02; A61M1/0209; A61M1/0218; A61M1/0222; A61M1/34; A61M1/3472; A61M1/36; A61M1/3693; A61M1/3696; B01D61/22; A61M2202/00; A61M2202/04; A61M2202/0405; A61M2202/0407
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
77 words
Apparatus for processing cells in a cell suspension comprising a membrane separating device connected to receive said cell suspension, said device including a membrane, said membrane being configured to pass cell-free fluid but not said cells through said membrane, said device having an outlet for a concentrated cell suspension, and means for receiving said concentrated cell suspension, said means including a centrifuge downstream of said separating device connected to receive said concentrated cell suspension from said outlet.
Claim 2
Dependent Claim
77 words
Apparatus for processing cells in a cell suspension comprising a membrane separating device connected to receive said cell suspension, said device including a membrane, said membrane being configured to pass cell-free fluid but not said cells through said membrane, said device having an outlet for a concentrated cell suspension, and means for receiving said concentrated cell suspension, said means including a centrifuge downstream of said separating device connected to receive said concentrated cell suspension from said outlet.
Claim 3
Dependent Claim
48 words
The apparatus of claim 1 further comprising pumps to control flow of said cell suspension through said separating device on one side of a membrane and flow of said cell-free fluid from the other side of said membrane so as to cause passage of said cell-free fluid therethrough.
Claim 4
Dependent Claim
16 words
The apparatus of claim 2 further comprising a pressure sensor upstream of said membrane separating device.
Claim 5
Dependent Claim
29 words
The apparatus of claim 2 further comprising a waste line connected to convey said cell-free fluid from said separating device, one said pump pumping liquid through said waste line.
Claim 6
Dependent Claim
26 words
The apparatus of claim 4 further comprising a bypass line between said waste line and a line connected to said outlet of said membrane separating device.
Claim 7
Dependent Claim
31 words
The apparatus of claim 1 further comprising a filter upstream of an inlet of said membrane separating device to filter said cell suspension prior to flowing into said membrane separating device.
Claim 8
Dependent Claim
25 words
The apparatus of claim 6 further comprising a bypass line around said filter and a clamp thereon to selectively block flow through said bypass line.
Claim 9
Dependent Claim
20 words
The apparatus of claim 1 further comprising a prime solution bag connected to the inlet of said membrane separating device.
Claim 10
Dependent Claim
17 words
The apparatus of claim 1 further comprising a cell suspension reservoir upstream of said membrane separating device.
Claim 11
Dependent Claim
22 words
The apparatus of claim 1 further comprising a centrifuge reservoir bag between the outlet of said membrane separating device and said centrifuge.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-29 | 1993-07-31 | 1994-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-29 | 1997-07-31 | 1998-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-29 | 2001-07-31 | 2002-01-30 | $7700.00 | Window Closed / Lapsed |