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US4895848A
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Treatment of alcoholism using 2-pyrimidinyl-1-piperazine derivative
Assignee: IROPONWERKE & Co KG A CORP OF GERMANY GmbH
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Filing: 1988-08-03
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Granted: 1990-01-23
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Expires: 2008-08-03
Abstract
Abstract A method for the treatment of alcoholism and medicaments used for such treatment wherein patients receive an effective amount of a 2-pyrimidinyl-1-piperazine derivative of the formula <IMAGE> in which n represents one of the numbers 2, 3, 4, 5 or 6, and R represents <IMAGE> in which R1, R2 and R3 each independently denote hydrogen or lower alkyl, or salts thereof.
Inventors
- 👤 Jorg Traber
- 👤 Klaus Opitz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:29
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/12; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61P; A61P25/00; A61P25/30
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
64 words
A method of treating alcoholism comprising administering to a patient who is an alcoholic an effective amount of a 2-pyrimidinyl-1-piperazine derivative of the formula ##STR8## in which n represents one of the numbers 2, 3, 4, 5 or 6, and R represents ##STR9## in which R 1 , R 2 and R 3 each independently denote hydrogen or lower alkyl, and/or the salts thereof.
Claim 2
Independent Claim
64 words
A method of treating alcoholism comprising administering to a patient who is an alcoholic an effective amount of a 2-pyrimidinyl-1-piperazine derivative of the formula ##STR8## in which n represents one of the numbers 2, 3, 4, 5 or 6, and R represents ##STR9## in which R 1 , R 2 and R 3 each independently denote hydrogen or lower alkyl, and/or the salts thereof.
Claim 3
Dependent Claim
25 words
A method according to claim 1, wherein R 1 , R 2 and R 3 each independently denote hydrogen or C 1 -C 6 -alkyl.
Claim 4
Dependent Claim
27 words
A method according to claim 1, wherein n represents 3 or 4 and R 1 , R 2 and R 3 each independently denote hydrogen or methyl.
Claim 5
Dependent Claim
13 words
A method according to claim 1, wherein the 2-pyrimidinyl-1-piperazine derivative is 2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)-butyl-1,1-benzoisothiazol-3(2H)-one 1,1-dioxide.
Claim 6
Dependent Claim
12 words
A method according to claim 1, wherein the -pyrimidinyl-1-piperazine derivative is 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-01-22 | 1993-07-24 | 1994-01-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-01-22 | 1997-07-24 | 1998-01-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-01-22 | 2001-07-24 | 2002-01-23 | $7700.00 | Window Closed / Lapsed |