Patent US4889842A successfully refreshed from Google Patents.
US4889842A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Concanavalin A dimers as therapeutic agents
Assignee: Individual
•
Filing: 1987-03-03
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Granted: 1989-12-26
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Expires: 2007-03-03
Abstract
Abstract Homogeneous dimeric forms of concanavalin A, including the dimer form of native concanavalin A and dimeric derivatives of concanavalin A, are effective immunoregulatory agents with a good balance of high activity and low toxicity. Immunoregulatory pharmaceutical materials composed of one or a mixture of such isolated dimeric materials are disclosed as are methods of inducing immunoregulation in mammals by administering to such mammals an effective immunoregulatory amount of such pharmaceutical materials.
Inventors
- 👤 Randall E. Morris
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:20
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/415; C07K14/42; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
31 words
A method of inducing immunoregulation in a mammal in need of immunoregulation comprising administering to such mammal an effective immunoregulatory amount of homogeneous concanavalin A dimer in a pharmaceutically acceptable carrier.
Claim 2
Independent Claim
31 words
A method of inducing immunoregulation in a mammal in need of immunoregulation comprising administering to such mammal an effective immunoregulatory amount of homogeneous concanavalin A dimer in a pharmaceutically acceptable carrier.
Claim 3
Independent Claim
34 words
A method of inducing immunoregulation in a mammal in need of immunoregulation comprising administering to such mammal an effective immunoregulatory amount of an at least 80% homogeneous concanavalin A in a pharmaceutically acceptable carrier.
Claim 4
Independent Claim
34 words
A method of inducing immunoregulation in a mammal in need of immunoregulation comprising administering to such mammal an effective immunoregulatory amount of an at least 80% homogeneous concanavalin A in a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
25 words
The method of inducing immunoregulation in a mammal in need of immunoregulation of claim 2 wherein the concanavalin A dimer comprises native concanavalin A dimer.
Claim 6
Dependent Claim
25 words
The method of inducing immunoregulation in a mammal in need of immunoregulation of claim 2 wherein the concanavalin A dimer comprises succinylated concanavalin A dimer.
Claim 7
Dependent Claim
24 words
A treated donor organ for transplantation comprising the organ in combination with a pharmaceutical preparation comprising an effective amount of homogeneous concanavalin A dimer.
Claim 8
Dependent Claim
24 words
A treated donor organ for transplantation comprising the organ in combination with a pharmaceutical preparation comprising an effective amount of homogeneous concanavalin A dimer.
Claim 9
Dependent Claim
24 words
A treated donor tissue for transplantation comprising the tissue in combination with a pharmaceutical preparation comprising an effective amount of homogeneous concanavalin A dimer.
Claim 10
Dependent Claim
24 words
A treated donor tissue for transplantation comprising the tissue in combination with a pharmaceutical preparation comprising an effective amount of homogeneous concanavalin A dimer.
Claim 11
Dependent Claim
25 words
The method of inducing immunoregulation in a mammal in need of immunoregulation of claim 2 wherein the concanavalin A dimer comprises acetylated concanavalin A dimer.
Claim 12
Dependent Claim
20 words
The method of inducing immunoregulation in a mammal in need of immunoregulation of claim 2 wherein the immunoregulation comprises immunosuppression.
Claim 13
Dependent Claim
20 words
The method of inducing immunoregulation in a mammal in need of immunoregulation of claim 4 wherein the immunoregulation comprises immunosuppression.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-25 | 1993-06-26 | 1993-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-25 | 1997-06-26 | 1997-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-25 | 2001-06-26 | 2001-12-26 | $7700.00 | Window Closed / Lapsed |