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Patent US4885282A successfully refreshed from Google Patents.
US4885282A
Expired / Lapsed
US
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Treatment of hyperhidrosis, ichthyosis and wrinkling
Assignee: DMK Pharmaceuticals Corp
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Filing: 1988-03-08
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Granted: 1989-12-05
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Expires: 2008-03-08
Abstract
Abstract Skin suffering from emotional hyperhidrosis, ichthyosis with or without keratosis, and intrinsic or photoaging wrinkling is treated with mono- or discarboxylic acids containing 4 to 18 carbon atoms, or certain mercapto derivatives, salts or esters thereof.
Inventors
- 👤 Carl R. Thornfeldt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:13
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/08; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/20; A61K31/21; A61K31/215; A61K31/22; A61K31/225; A61K31/23; A61K31/70; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/36; A61K8/362; A61K8/37; A61K8/375; A61K8/46; A61K8/60; A61P; A61P17/00; A61Q15/00
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
52 words
A method for the treatment of skin suffering from hyperhidrosis, ichthyosis or wrinkling, said method comprising applying to the affected area a therapeutically effective amount of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and esters thereof.
Claim 2
Independent Claim
52 words
A method for the treatment of skin suffering from hyperhidrosis, ichthyosis or wrinkling, said method comprising applying to the affected area a therapeutically effective amount of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and esters thereof.
Claim 3
Dependent Claim
16 words
A method in accordance with claim 1 in which said mono- and dicarboxylic acids are straight-chain.
Claim 4
Dependent Claim
23 words
A method in accordance with claim 1 in which said mono- and dicarboxylic acids are straight-chain and contain 7 to 13 carbon atoms.
Claim 5
Dependent Claim
22 words
A method in accordance with claim 1 in which said compound is a straight-chain dicarboxylic acid having 7 to 13 carbon atoms.
Claim 6
Dependent Claim
28 words
A method in accordance with claim 1 in which said compound is selected from the group consisting of azelaic acid, mercapto derivatives thereof, salts thereof, and esters thereof.
Claim 7
Dependent Claim
28 words
A method in accordance with claim 1 in which said esters are selected from the group consisting of alkyl esters and esters prepared from polyols, oligosaccharides and polysaccharides.
Claim 8
Dependent Claim
21 words
A method in accordance with claim 1 in which said esters are selected from the group consisting of polyols and oligosaccharides.
Claim 9
Dependent Claim
25 words
A method in accordance with claim 1 in which said esters are selected from the group consisting of glycerol, polyethylene glycol, polypropylene glycol and sucrose.
Claim 10
Dependent Claim
33 words
A method in accordance with claim 1 in which said compound is a member selected from the group consisting of monoglyceride and monosucrose esters of dicarboxylic acids having 4 to 18 carbon atoms.
Claim 11
Dependent Claim
14 words
A method in accordance with claim 1 in which said compound is azelaic acid.
Claim 12
Dependent Claim
27 words
A method in accordance with claim 1 in which said compound is a member selected from the group consisting of monoglyceride and monosucrose esters of azelaic acid.
Claim 13
Dependent Claim
32 words
A method in accordance with claim 1 in which said compound is in the form of a dermatological formulation of which said compound comprises from about 0.1% to about 40% by weight.
Claim 14
Dependent Claim
32 words
A method in accordance with claim 1 in which said compound is in the form of a dermatological formulation of which said compound comprises from about 3% to about 20% by weight.
Claim 15
Dependent Claim
34 words
A method in accordance with claim 1 in which said compound is applied topically in a form selected from the group consisting of a lotion, a cream, an unguent, an ointment and a solution.
Claim 16
Independent Claim
65 words
A method for the treatment of skin suffering from hyperhidrosis, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 17
Independent Claim
65 words
A method for the treatment of skin suffering from hyperhidrosis, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 18
Dependent Claim
39 words
A method in accordance with claim 15 in which said compound is a member selected from the group consisting of dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 19
Dependent Claim
30 words
A method in accordance with claim 15 in which said compound is a member selected from the group consisting of azelaic acid, the monoglyceride ester and the monosucrose ester thereof.
Claim 20
Independent Claim
65 words
A method for the treatment of skin suffering from ichthyosis, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 21
Independent Claim
65 words
A method for the treatment of skin suffering from ichthyosis, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 4 to 18 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 22
Dependent Claim
39 words
A method in accordance with claim 18 in which said compound is a member selected from the group consisting of dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 23
Dependent Claim
30 words
A method in accordance with claim 18 in which said compound is a member selected from the group consisting of azelaic acid, the monoglyceride ester and the monosucrose ester thereof.
Claim 24
Independent Claim
65 words
A method for the treatment of skin suffering from keratosis pilaris, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 25
Independent Claim
65 words
A method for the treatment of skin suffering from keratosis pilaris, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 26
Dependent Claim
39 words
A method in accordance with claim 21 in which said compound is a member selected from the group consisting of dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 27
Dependent Claim
30 words
A method in accordance with claim 21 in which said compound is a member selected from the group consisting of azelaic acid, the monoglyceride ester and the monosucrose ester thereof.
Claim 28
Independent Claim
70 words
A method for the treatment of skin suffering from wrinkling due to intrinsic aging or photoaging, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 29
Independent Claim
70 words
A method for the treatment of skin suffering from wrinkling due to intrinsic aging or photoaging, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from 0.1% to about 40% by weight of a compound selected from the group consisting of mono- and dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 30
Dependent Claim
39 words
A method in accordance with claim 24 in which said compound is a member selected from the group consisting of dicarboxylic acids having 7 to 13 carbon atoms, mercapto derivatives thereof, salts thereof, and polyol and oligosaccharide esters thereof.
Claim 31
Dependent Claim
30 words
A method in accordance with claim 24 in which said compound is a member selected from the group consisting of azelaic acid, the monoglyceride ester and the monosucrose ester thereof.
Claim 32
Independent Claim
47 words
A method for the treatment of skin suffering from hyperhidrosis, ichthyosis vulgaris with or without keratosis pilaris, or wrinkling, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 5% to about 20% by weight of azelaic acid.
Claim 33
Independent Claim
47 words
A method for the treatment of skin suffering from hyperhidrosis, ichthyosis vulgaris with or without keratosis pilaris, or wrinkling, said method comprising applying to the affected area a therapeutically effective amount of a dermatological formulation containing from about 5% to about 20% by weight of azelaic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-04 | 1993-06-05 | 1993-12-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-04 | 1997-06-05 | 1997-12-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-04 | 2001-06-05 | 2001-12-05 | $7700.00 | Window Closed / Lapsed |