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US4876084A Expired / Lapsed US ⏱️ 0.0 years remaining

P-hydroxycinnamamide derivatives and melanin inhibitor comprising the same

Assignee: Kao Corp
•
Filing: 1987-07-23
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Granted: 1989-10-24
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Expires: 2007-07-23
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Abstract

Abstract A novel melanin inhibitor comprising as an active component a p-hydroxycinnamamide derivative of the following general formula (I) ##STR1## in which R 1 represents a hydrogen atom or a 2-hydroxyethyl group, and R 2 represents a hydroxymethyl group or a carboxyl group. The melanin inhibitor may take various forms such as a lotion, an emulsion, a cream, an ointment, a gel and the like, and it is locally applied onto affected parts such as spots and freckles on the skin, and a pigmental deposition after sunburn.

Inventors

  • 👤 Kimihiko Hori
  • 👤 Koichi Nakamura
  • 👤 Michio Kawai
  • 👤 Itsuro Motegi
  • 👤 Genji Imokawa
  • 👤 Naotake Takaishi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 19:00
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61Q; A61Q17/00; A61Q17/04; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/42

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 21 words
A p-hydroxycinnamamide derivative of the following formula (II) ##STR8## in which R 1 represents a hydrogen atom or a 2-hydroxyethyl group.
Claim 2
Dependent Claim 21 words
A p-hydroxycinnamamide derivative of the following formula (II) ##STR8## in which R 1 represents a hydrogen atom or a 2-hydroxyethyl group.
Claim 3
Dependent Claim 30 words
A melanin inhibitor composition, comprising: an active component of a p-hydroxycinnamamide derivative of the formula: ##STR9## wherein R 1 is hydrogen or a 2-hydroxyethyl group in a cosmetically acceptable vehicle.
Claim 4
Dependent Claim 30 words
A melanin inhibitor composition, comprising: an active component of a p-hydroxycinnamamide derivative of the formula: ##STR9## wherein R 1 is hydrogen or a 2-hydroxyethyl group in a cosmetically acceptable vehicle.

References Cited (Backward Citations)

DE2015447A1 Cited
FR2545355A1 Cited
GB2141626A Cited
GB2150436A Cited
JPS6219510A Cited
JPS6256459A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-10-23 1993-04-24 1993-10-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-10-23 1997-04-24 1997-10-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-10-23 2001-04-24 2001-10-24 $7700.00 Window Closed / Lapsed

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