Patent US4871660A successfully refreshed from Google Patents.
US4871660A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Luminescence immuno-test kits, method for stabilizing same and quality control thereof
Assignee: HENNING BERLIN CHEMIE- und PHARMAWERK KOMTURSTRASSE 58- 62 D-1000 BERLIN 42 GERMANY GmbH
•
Filing: 1987-03-11
•
Granted: 1989-10-03
•
Expires: 2007-03-11
Abstract
Abstract Luminescence immuno-test kits consist of an antigen or antibody capable of showing luminescence and labelled with phthalic hydrazides, an antibody or antigen preferably bound to a carrier and an oxidizing reagent inducing the luminescence to occur and are characterized in that the oxidizing reagent is a pre-fabricated solution of catalase, optionally stabilized by a bacteriostat, and the initiator is a pre-fabricated peroxide solution which is at least 20 minutes old. These luminescence immuno-tests are particularly stable and may be subjected to a quality control in a simple and inexpensive way.
Inventors
- 👤 Andre Gadow
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 02:56
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/58; G01N33/582; Y; Y10; Y10S; Y10S435/00; Y10S435/81; Y10S435/968; Y10S436/00; Y10S436/807; Y10S436/808
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
60 words
Luminescence immuno-test kit consisting essentially of an antigen or antibody labeled with a phthalic hydrazide capable of showing luminescence, an antibody or antigen and an oxidizing agent inducing the luminescence to occur, characterized in that the oxidizing agent is a pre-fabricated solution of catalase and that an initiator is a pre-fabricated peroxide solution which is at least 20 minutes old.
Claim 2
Dependent Claim
60 words
Luminescence immuno-test kit consisting essentially of an antigen or antibody labeled with a phthalic hydrazide capable of showing luminescence, an antibody or antigen and an oxidizing agent inducing the luminescence to occur, characterized in that the oxidizing agent is a pre-fabricated solution of catalase and that an initiator is a pre-fabricated peroxide solution which is at least 20 minutes old.
Claim 3
Dependent Claim
16 words
Kit according to claim 1 wherein the solution of catalase is stabilized by a bacteriostatic agent.
Claim 4
Dependent Claim
15 words
Kit according to claim 2, characterized in that sodium azide is used as bacteriostatic agent.
Claim 5
Dependent Claim
16 words
Kit according to claim 1, characterized in that a complexed peroxide is used as the peroxide.
Claim 6
Dependent Claim
13 words
Kit according to claim 2, wherein a complexed peroxide is used as peroxide.
Claim 7
Dependent Claim
22 words
A kit according to claim 1 wherein said catalase solution additionally contains 1 to 10% ethanol and 0.1 to 5 g/l EDTA.
Claim 8
Dependent Claim
22 words
A kit according to claim 2 wherein said catalase solution additionally contains 1 to 10% ethanol and 0.1 to 5 g/l EDTA.
Claim 9
Dependent Claim
74 words
Method for providing stablized luminescence immuno-test kits consisting essentially of an antigen or antibody labeled with a phthalic hydrazide capable of showing luminescence, an antibody or antigen and an oxidizing reagent inducing said luminescence to occur wherein stabilization is effected by adding said oxidizing reagent in the form of a pre-fabricated solution of catalase, and an initiator is added in the form of a pre-fabricated peroxide solution which is at least 20 minutes old.
Claim 10
Dependent Claim
74 words
Method for providing stablized luminescence immuno-test kits consisting essentially of an antigen or antibody labeled with a phthalic hydrazide capable of showing luminescence, an antibody or antigen and an oxidizing reagent inducing said luminescence to occur wherein stabilization is effected by adding said oxidizing reagent in the form of a pre-fabricated solution of catalase, and an initiator is added in the form of a pre-fabricated peroxide solution which is at least 20 minutes old.
Claim 11
Dependent Claim
15 words
Method of claim 8 wherein the solution of catalase is stabilized by a bacteriostatic agent.
Claim 12
Dependent Claim
15 words
Method according to claim 9, characterized in that sodium azide is used as bacteriostatic agent.
Claim 13
Dependent Claim
16 words
Method according to claim 8, characterized in that a complexed peroxide is used as the peroxide.
Claim 14
Dependent Claim
16 words
Method according to claim 10, characterized in that a complexed peroxide is used as the peroxide.
Claim 15
Dependent Claim
22 words
The method according to claim 8 wherein said catalase solution additionally contains 1 to 10% ethanol and 0.1 to 5 g/l EDTA.
Claim 16
Dependent Claim
22 words
The method according to claim 10 wherein said catalase solution additionally contains 1 to 10% ethanol and 0.1 to 5 g/l EDTA.
References Cited (Backward Citations)
US2689203A
Cited
US4104029A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-10-02 | 1993-04-03 | 1993-10-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-10-02 | 1997-04-03 | 1997-10-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-10-02 | 2001-04-03 | 2001-10-03 | $7700.00 | Window Closed / Lapsed |