US4859677A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Nucleoside analogues having antiviral activity
Assignee: University of Kansas
•
Filing: 1987-04-17
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Granted: 1989-08-22
•
Expires: 2007-04-17
Abstract
Abstract Compounds of the formula (I) ##STR1## wherein X is ═N-- or ═CH-- and physiologically acceptable salts and solvents thereof which have antiviral activity, a process for the preparation of the compounds and intermediates thereof, pharmaceutical compositions containing the compounds and a method for inhibiting the propagation of virus using the compounds.
Inventors
- 👤 Ronald T. Borchardt
- 👤 David R. Borcherding
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 00:32
CPC Classifications
C; C07; C07D; C07D473/00; C07D471/00; C07D471/02; C07D471/04
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
20 words
A compound of the formula (I) wherein X is ═N-- or ═CH-- or a physiologically acceptable salt or solvate thereof.
Claim 2
Dependent Claim
20 words
A compound of the formula (I) wherein X is ═N-- or ═CH-- or a physiologically acceptable salt or solvate thereof.
Claim 3
Dependent Claim
10 words
The compound of claim I which has the formula ##STR32##
Claim 4
Dependent Claim
9 words
The compound of claim 2, wherein X is ═N--.
Claim 5
Dependent Claim
9 words
The compound of claim 2, wherein X is ═CH--.
Claim 6
Dependent Claim
19 words
An antiviral composition comprising an effective antiviral amount of the compound of claim 1, and a pharmaceutically effective carrier.
Claim 7
Dependent Claim
19 words
An antiviral composition comprising an effective antiviral amount of the compound of claim 2, and a pharmaceutically effective carrier.
Claim 8
Dependent Claim
9 words
The composition of claim 6, wherein X is ═N--.
Claim 9
Dependent Claim
9 words
The composition of claim 6, wherein X is ═CH--.
Claim 10
Dependent Claim
15 words
The composition of claim 7 which contains an effective anti poxvirus amount of said compound.
Claim 11
Dependent Claim
15 words
The composition of claim 8 which contains an effective anti poxvirus amount of said compound.
Claim 12
Dependent Claim
15 words
The composition of claim 7 which contains an effective anti reovirus amount of said compound.
Claim 13
Dependent Claim
15 words
The composition of claim 8 which contains an effective anti reovirus amount of said compound.
Claim 14
Dependent Claim
20 words
The composition of claim 7 which contains an effective anti measles, parainfluenza or vesicular stomatitis virus amount of said compound.
Claim 15
Dependent Claim
20 words
The composition of claim 8 which contains an effective anti measles, parainfluenza or vesicular stomatitis virus amount of said compound.
Claim 16
Dependent Claim
34 words
A method for treating viral infections which comprises administering an effective antiviral amount of the composition of claim 7 to a subject infected with poxvirus, reovirus, measles virus, parainfluenza virus or vesicular stomatitis virus.
Claim 17
Dependent Claim
20 words
A pharamaceutical composition comprising 0.1 to 99% by weight of the compound of claim 1 and a pharmaceutically effective carrier.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-08-21 | 1993-02-20 | 1993-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-08-21 | 1997-02-20 | 1997-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-08-21 | 2001-02-20 | 2001-08-22 | $7700.00 | Window Closed / Lapsed |