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US4856533A
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Vacuum blood-collection tube
Assignee: Sekisui Chemical Co Ltd
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Filing: 1986-01-28
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Granted: 1989-08-15
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Expires: 2006-01-28
Abstract
Abstract A vacuum blood-collection tube comprising a tube-shaped vessel having an opening through which air can be removed, and a plug that makes the opening air-tight to maintain low-pressure conditions inside the said vessel, the raw materials of the said vessel being polyethyleneterephthalate, a copolymer of polyethyleneterephthalate, or an acrylonitrile resin, and the inner walls of said vessel incorporating a hydrophilic substance that is either difficult or impossible to dissolve in water and that prevent blood clots from adhering to the inner walls of said tube, a water-soluble substance, and a adsorptive inorganic substance.
Inventors
- 👤 Hideo Anraku
- 👤 Yoshikata Shoji
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 23:30
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/14; B; B01; B01L; B01L3/00; B01L3/50; B01L3/508; B01L3/5082; A61L; A61L31/00; A61L31/08; A61L31/10
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
93 words
A vacuum blood-collection tub comprising a tube-shaped vessel having an opening through which air can be removed, and a plug that makes the opening air-tight to maintain low-pressure conditions inside the said vessel, the raw materials of the said vessel being polyethyleneterephthalate, a copolymer of polyethyleneterephthalate, or an acrylonitrile resin, and the inner walls of said vessel incorporating a hydrophilic substance that is either difficult or impossible to dissolve in water and that prevents blood clots from adhering to the inner walls of said tube, a water-soluble substance, and an adsorptive inorganic substance.
Claim 2
Dependent Claim
93 words
A vacuum blood-collection tub comprising a tube-shaped vessel having an opening through which air can be removed, and a plug that makes the opening air-tight to maintain low-pressure conditions inside the said vessel, the raw materials of the said vessel being polyethyleneterephthalate, a copolymer of polyethyleneterephthalate, or an acrylonitrile resin, and the inner walls of said vessel incorporating a hydrophilic substance that is either difficult or impossible to dissolve in water and that prevents blood clots from adhering to the inner walls of said tube, a water-soluble substance, and an adsorptive inorganic substance.
Claim 3
Dependent Claim
34 words
A vacuum blood-collection tube according to claim 1, wherein said adsorptive inorganic substance has an absorption amount of linseed oil or 20-40 ml/100 g and a BET-specific surface area of 5,000-30,000 cm 2 /g.
Claim 4
Dependent Claim
17 words
A vacuum blood-collection tube according to claim 1, wherein a partitioning agent is used within said vessel.
Claim 5
Dependent Claim
24 words
A vacuum blood-collection tube according to claim 3, wherein said partitioning agent contains both agents that confer the property of thixotropy and viscous liquid.
Claim 6
Dependent Claim
20 words
A vacuum blood-collection tube according to claim 3, wherein said partitioning agent contains thixotropy-conferring agents, viscous liquids and water-insoluble amines.
Claim 7
Dependent Claim
70 words
A vacuum blood-collecting tube according to any one of claims 1-5, wherein said tube-shaped vessel is wrapped so as to be air-tight in a plastic wrapping that acts as a gas barrier, the space between said tube-shaped vessel and said wrapping being filled with a gas that does not readily permeate either the vessel material or the wrapping material, and the pressure of said gas being greater than atmospheric pressure.
Claim 8
Dependent Claim
35 words
A vacuum blood-collection tube according to claim 6, wherein the amount of said gas that permeates both the tube-shaped vessel and the wrapping is 2 cc/m 2 ·24 hrs atm or less at 23° C.
Claim 9
Dependent Claim
16 words
A vacuum blood-collection tube according to claim 7, wherein said wrapping is made of a laminate.
Claim 10
Dependent Claim
42 words
A vacuum blood-collection tube according to claim 1, wherein said hydrophilic substance that is either difficult or impossible to dissolve in water is a substance selected from the group consisting of dimethylpolysiloxane modified with polar substitutents, and methylhydrogenpolysiloxane modified with polar substituents.
Claim 11
Dependent Claim
26 words
A vacuum blood-clotting tube according to claim 9, wherein said adsorptive inorganic substance is selected from the group consisting of glass, silica, kaolin, cerite and benthonite.
Claim 12
Dependent Claim
30 words
A vacuum blood-clotting tube according to claim 10, wherein said water-soluble substance is selected from the group consisting of ethylene glycol, glycerin, sorbitol, polyethylene oxide, polyvinyl alcohol and polyvinyl pyrrolidone.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-08-14 | 1993-02-13 | 1993-08-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-08-14 | 1997-02-13 | 1997-08-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-08-14 | 2001-02-13 | 2001-08-15 | $7700.00 | Window Closed / Lapsed |