US4853375A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of lowering intraocular (eye) pressure
Assignee: TRUSTEES OF UNIVERSITY OF PENNSYLVANIA A CORP OF
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Filing: 1987-09-16
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Granted: 1989-08-01
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Expires: 2007-09-16
Abstract
Abstract A method of lowering intraocular pressure in the eye of a human or an animal, the method involving administering to the eye, an agent comprising an amount of tetracycline or a tetracycline related compound, such as demeclocycline, sufficient to achieve a significant lowering of intraocular pressure.
Inventors
- 👤 Theodore Krupin
- 👤 Richard A. Stone
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 17:06
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/65; A61P; A61P27/00; A61P27/02; A61P27/06; A61P9/00; A61P9/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
49 words
A method of lowering intraocular pressure in the eye of a human or an animal, said method comprising administering to said eye, a therapeutically effective amount of tetracycline or a derivative of the tetracycline series having the property to achieve a significant lowering of intraocular pressure in the eye.
Claim 2
Independent Claim
49 words
A method of lowering intraocular pressure in the eye of a human or an animal, said method comprising administering to said eye, a therapeutically effective amount of tetracycline or a derivative of the tetracycline series having the property to achieve a significant lowering of intraocular pressure in the eye.
Claim 3
Dependent Claim
10 words
The method of claim 1 wherein said agent comprises demeclocycline.
Claim 4
Dependent Claim
27 words
The method of claim 1 wherein said agent is applied topically to the eye in the form of an ointment, drops, or other suitable topical delivery system.
Claim 5
Dependent Claim
19 words
The method of claim 1 wherein said agent is delivered by way of an injection or intravenously or orally.
Claim 6
Dependent Claim
23 words
The method of claim 1 wherein said agent is selected from the group consisting of demeclocycline, tetracycline, oxytetracycline, minocycline, methacycine, chlorotetracycline and doxycycline.
References Cited (Backward Citations)
US4666897A
Cited
US4748189A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-31 | 1993-01-30 | 1993-08-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-31 | 1997-01-30 | 1997-08-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-31 | 2001-01-30 | 2001-08-01 | $7700.00 | Window Closed / Lapsed |