Patent US4853372A successfully refreshed from Google Patents.
US4853372A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Non-aqueous ivermectin formulation with improved antiparasitic activity
Assignee: Merck and Co Inc
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Filing: 1986-11-28
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Granted: 1989-08-01
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Expires: 2006-11-28
Abstract
Abstract Ivermectin, an antiparasitic agent which is insoluble and unstable in water, is formulated in glycerol formal and propylene glycol. These liquid formulations are suitable for parenteral administration for the treatment of parasitic infections and demonstrate improved efficacy and a broadened spectrum over previous formulations.
Inventors
- 👤 James B. Williams
- 👤 Russell U. Nesbitt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 07:58
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/22; A61K9/00; A61K9/0012; A61K9/0019; C; C07; C07H; C07H19/00; C07H19/01
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
33 words
An endo or ectoparasiticidal parenteral formulation consisting of from 0.1 to 20% by weight of ivermectin dissolved in a combination of propylene glycol and glycerol formal in a ratio of about 60:40 v/v.
Claim 2
Dependent Claim
33 words
An endo or ectoparasiticidal parenteral formulation consisting of from 0.1 to 20% by weight of ivermectin dissolved in a combination of propylene glycol and glycerol formal in a ratio of about 60:40 v/v.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-31 | 1993-01-30 | 1993-08-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-31 | 1997-01-30 | 1997-08-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-31 | 2001-01-30 | 2001-08-01 | $7700.00 | Window Closed / Lapsed |