US4849172A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Optical sensor
Assignee: Terumo Cardiovascular Systems Corp
•
Filing: 1988-01-29
•
Granted: 1989-07-18
•
Expires: 2008-01-29
Abstract
Abstract An optical sensor which is a gas permeable silicone polymeric matrix having at least one optical indicator therein for providing an optical signal in response to excitation light. The optical indicator essentially comprises a mixture of non-polar derivatives of a polynuclear aromatic compound.
Inventors
- 👤 Masao Yafuso
- 👤 Cheng F. Yan
- 👤 Henry K. Hui
- 👤 William W. Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 02:28
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/62; G01N21/63; G01N21/64; G01N21/6428; G01N21/75; G01N21/77; G01N21/7703; G01N2021/7706; G01N2021/772; G01N2021/773; G01N2021/7769; G01N2021/7786; Y; Y10; Y10T; Y10T436/00; Y10T436/20; Y10T436/207497; Y10T436/209163; Y10T436/25; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 35
Claim 1
Independent Claim
64 words
An optical sensor for a blood constituent of interest consisting essentially of: a gas permeable, crosslinked silicone polymeric matrix having therein at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound, each of said derivatives providing a portion of an optical signal in response to excitation light when in the presence of a blood constituent of interest.
Claim 2
Dependent Claim
64 words
An optical sensor for a blood constituent of interest consisting essentially of: a gas permeable, crosslinked silicone polymeric matrix having therein at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound, each of said derivatives providing a portion of an optical signal in response to excitation light when in the presence of a blood constituent of interest.
Claim 3
Dependent Claim
21 words
A sensor of claim 1 wherein: said polynuclear aromatic compound is selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene.
Claim 4
Dependent Claim
12 words
A sensor of claim 1 wherein: said polynuclear aromatic compound is decacyclene.
Claim 5
Dependent Claim
110 words
A sensor of claim 1 wherein said polynuclear aromatic compound is derivatized with at least one material selected from the group consisting of aliphatic hydrocarbons, cycloalkyl and cycloalkenyl hydrocarbons, alkyl and alkenyl spiro hydrocarbons, aromatic hydrocarbons, aliphatic-aliphatic ethers, aliphatic-aromatic ethers, aromatic-aromatic ethers, aliphatic-aliphatic ketones, aliphatic-aromatic ketones and aromatic-aromatic ketones; provided that said aliphatic groups are selected from the group consisting of C 1-C 18 straight and branched chain alkyl, alkenyl and alkynyl groups, and said aromatic groups are selected from the group consisting of unsubstituted and substituted aromatic groups where said substituents on said substituted aromatic groups are selected from the group consisting of alkyl, alkenyl, fluoro and chloro groups.
Claim 6
Dependent Claim
81 words
A sensor of claim 4 wherein: said at least one material is selected from the group consisting of aliphatic hydrocarbons, cycloalkyl and cycloalkenyl hydrocarbons, alkyl and alkenyl spiro hydrocarbons, aromatic hydrocarbons and substituted aromatic hydrocarbons; provided that said aliphatic groups are selected from the group consisting of C 1-C 18 straight and branched chain alkyl, alkenyl, and alkynyl groups, and said substituents on said substituted aromatic groups are selected from the group consisting of alkyl, alkenyl alkynyl, fluoro and chloro groups.
Claim 7
Dependent Claim
11 words
A sensor of claim 1 wherein: said derivatives are non-polar derivatives.
Claim 8
Dependent Claim
26 words
A sensor of claim 1 wherein: said mixture of derivatives of said polynuclear aromatic compound is a mixture of t-butyl derivatives of said polynuclear aromatic compound.
Claim 9
Dependent Claim
19 words
A sensor of claim 7 wherein: said polynuclear aromatic compound is decacyclene and said mixture is soluble in hexane.
Claim 10
Dependent Claim
15 words
A sensor of claim 8 wherein: said silicone polymeric matrix is a dimethylsiloxane polymeric matrix.
Claim 11
Dependent Claim
21 words
A sensor of claim 1 wherein: said silicone polymeric matrix is selected from the group consisting of dimethylsiloxane, diphenylsiloxane and dimethyldiphenylsiloxane.
Claim 12
Dependent Claim
25 words
A sensor of claim 1 wherein: said mixture of derivatives of said polynuclear aromatic compound includes at least three derivatives of said polynuclear aromatic compound.
Claim 13
Dependent Claim
41 words
A sensor of claim 1 wherein: said mixture of derivatives of said polynuclear aromatic compound is present in said silicone polymeric matrix in a concentration of at least about 1.2 mg of said mixture per gram of said silicone polymeric matrix.
Claim 14
Dependent Claim
23 words
An optical sensor consisting essentially of: a gas permeable, crosslinked dimethylsiloxane polymeric matrix having a mixture of t-butyl derivatives of decacyclene present therein.
Claim 15
Dependent Claim
23 words
An optical sensor consisting essentially of: a gas permeable, crosslinked dimethylsiloxane polymeric matrix having a mixture of t-butyl derivatives of decacyclene present therein.
Claim 16
Dependent Claim
22 words
The sensor of claim 13 wherein: said mixture of derivatives includes at least three of said derivatives and is soluble in hexane.
Claim 17
Dependent Claim
26 words
The sensor of claim 13 wherein: said mixture is present in an amount of least 1.2 mg of said mixture per gram of said polymeric matrix.
Claim 18
Independent Claim
134 words
An apparatus for measuring a blood constituent of interest consisting essentially of: an optical sensor consisting essentially of a gas permeable, crosslinked silicone matrix having therein at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound, each of said derivatives providing a portion of an optical signal in response to excitation light when exposed to a blood constituent of interest, said matrix being permeable to such a blood constituent of interest; means for holding the optical sensor so that it can be exposed to blood; and optical fiber means for delivering excitation light to the optical sensor so that the optical sensor can provide an optical signal indicative of a characteristic of a constituent of interest and of transmitting such an optical signal from the optical sensor.
Claim 19
Independent Claim
134 words
An apparatus for measuring a blood constituent of interest consisting essentially of: an optical sensor consisting essentially of a gas permeable, crosslinked silicone matrix having therein at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound, each of said derivatives providing a portion of an optical signal in response to excitation light when exposed to a blood constituent of interest, said matrix being permeable to such a blood constituent of interest; means for holding the optical sensor so that it can be exposed to blood; and optical fiber means for delivering excitation light to the optical sensor so that the optical sensor can provide an optical signal indicative of a characteristic of a constituent of interest and of transmitting such an optical signal from the optical sensor.
Claim 20
Dependent Claim
11 words
The apparatus of claim 16 wherein: said derivatives are hydrocarbon derivatives.
Claim 21
Dependent Claim
21 words
The apparatus of claim 16 wherein: said at least one optical indicator consists essentially of a mixture of derivatives of decacyclene.
Claim 22
Dependent Claim
18 words
The apparatus of claim 18 wherein: said derivatives are t-butyl derivatives and said mixture is soluble in hexane.
Claim 23
Dependent Claim
74 words
An optical sensor for a blood constituent of interest consisting essentially of: a gas permeable, crosslinked silicone polymeric matrix having at least one optical indicator therein for providing an optical signal in response to excitation light when in the presence of a blood constituent of interest, said at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene.
Claim 24
Dependent Claim
74 words
An optical sensor for a blood constituent of interest consisting essentially of: a gas permeable, crosslinked silicone polymeric matrix having at least one optical indicator therein for providing an optical signal in response to excitation light when in the presence of a blood constituent of interest, said at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene.
Claim 25
Dependent Claim
12 words
A sensor of claim 20 wherein said polynuclear aromatic compound is decacyclene.
Claim 26
Dependent Claim
11 words
A sensor of claim 21 wherein said derivatives are t-butyl derivatives.
Claim 27
Dependent Claim
15 words
A sensor of claim 22 wherein said silicone polymeric matrix is a dimethylsiloxane polymeric matrix.
Claim 28
Dependent Claim
12 words
A sensor of claim 20 wherein said polynuclear aromatic compound is benzo-ghi-perylene.
Claim 29
Dependent Claim
11 words
A sensor of claim 24 wherein said derivatives are t-butyl derivatives.
Claim 30
Dependent Claim
65 words
An optical sensor consisting essentially of a gas permeable, crosslinked dimethylsiloxane polymeric matrix having an optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene dispersed therein, said optical indicator being present in an amount of at least about 1.2 mg of said indicator per gram of said dimethylsiloxane polymerix matrix.
Claim 31
Dependent Claim
65 words
An optical sensor consisting essentially of a gas permeable, crosslinked dimethylsiloxane polymeric matrix having an optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene dispersed therein, said optical indicator being present in an amount of at least about 1.2 mg of said indicator per gram of said dimethylsiloxane polymerix matrix.
Claim 32
Independent Claim
144 words
An apparatus for measuring a blood constituent of interest consisting essentially of: an optical sensor consisting essentially of a gas permeable, crosslinked silicone matrix having at least one optical indicator therein for providing an optical signal in response to excitation light when exposed to a blood constituent of interest, said at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene, said matrix being permeable to such a blood constituent of interest; means for holding the optical sensor so that it can be exposed to blood; and optical fiber means for delivering excitation light to the optical sensor so that the optical sensor can provide an optical sensor indicative of a characteristic of a constituent of interest and for transmitting such an optical signal from the optical sensor.
Claim 33
Independent Claim
144 words
An apparatus for measuring a blood constituent of interest consisting essentially of: an optical sensor consisting essentially of a gas permeable, crosslinked silicone matrix having at least one optical indicator therein for providing an optical signal in response to excitation light when exposed to a blood constituent of interest, said at least one optical indicator consisting essentially of a mixture of derivatives of a polynuclear aromatic compound selected from the group consisting of decacyclene, benzo-ghi-perylene and coronene, said matrix being permeable to such a blood constituent of interest; means for holding the optical sensor so that it can be exposed to blood; and optical fiber means for delivering excitation light to the optical sensor so that the optical sensor can provide an optical sensor indicative of a characteristic of a constituent of interest and for transmitting such an optical signal from the optical sensor.
Claim 34
Dependent Claim
18 words
The apparatus of claim 27 wherein: said at least one optical indicator consists essentially of derivatives of decacyclene.
Claim 35
Dependent Claim
11 words
The apparatus of claim 28 wherein said derivatives are t-butyl derivatives.
References Cited (Backward Citations)
US3725658A
Cited
US4003707A
Cited
US4399099A
Cited
US4557900A
Cited
EP0105870A2
Cited
US4587101A
Cited
US4657736A
Cited
EP0109959B1
Cited
GB2132348A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-17 | 1993-01-16 | 1993-07-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-17 | 1997-01-16 | 1997-07-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-17 | 2001-01-16 | 2001-07-18 | $7700.00 | Window Closed / Lapsed |