US4847077A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Controlled release pharmaceutical preparations
Assignee: Fisons Corp
•
Filing: 1987-01-27
•
Granted: 1989-07-11
•
Expires: 2007-01-27
Abstract
Abstract Controlled release pharmaceutical preparations containing coated sulfonic acid cationic exchange resin drug complex particles, the resin particles having been treated, prior to coating, with about 15 to 25% by weight of glycerin, based on the combined weight of the glycerin and the drug resin complex particles.
Inventors
- 👤 Yegnaswami Raghunathan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 20:49
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/585; A61K9/1629; A61K9/1635; A61K9/48; A61K9/50; A61K9/5005; A61K9/5021; A61K9/5036; A61K9/5042; A61K9/5047
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
54 words
Sulfonic acid catonic exchange resin particles having a monobasic drug adsorbed thereon, which resin particles have been treated with from about 15 to about 30 percent by weight of glycerin, based on the combined weight of the glycerin and the drug-resin particles, which particles have been subsequently individually coated with a water-permeable diffusion barrier.
Claim 2
Dependent Claim
54 words
Sulfonic acid catonic exchange resin particles having a monobasic drug adsorbed thereon, which resin particles have been treated with from about 15 to about 30 percent by weight of glycerin, based on the combined weight of the glycerin and the drug-resin particles, which particles have been subsequently individually coated with a water-permeable diffusion barrier.
Claim 3
Dependent Claim
36 words
Resin particles as in claim 1, which resin particles have been treated with from about 15 to about 25 percent by weight of glycerin, based on the combined weight of the glycerin and the drug-resin particles.
Claim 4
Dependent Claim
13 words
Resin particles according to claim 1, wherein the diffusion barrier coating comprises ethylcellulose.
Claim 5
Dependent Claim
57 words
A process for enhancing the coatability of sulfonic acid catonic exchange resin particles which comprises contacting said particles with an aqueous solution of glycerin containing from about 20% to about 30% by weight of glycerin, based on the combined weight of the glycerin and the particles, and subsequently individually coating said particles with a water-permeable diffusion barrier.
Claim 6
Dependent Claim
57 words
A process for enhancing the coatability of sulfonic acid catonic exchange resin particles which comprises contacting said particles with an aqueous solution of glycerin containing from about 20% to about 30% by weight of glycerin, based on the combined weight of the glycerin and the particles, and subsequently individually coating said particles with a water-permeable diffusion barrier.
Claim 7
Dependent Claim
65 words
A pharmaceutical preparation comprising sulfonic acid cationic exchange resin particles having a pharmacologically active monobasic drug adsorbed thereon to form drug-resin complex particles, which resin particles have been treated with from about 15 to about 25 percent by weight of glycerin, based on the combined weight of the glycerin and the complex particles, and subsequently individually coated with a water-permeable diffusion barrier comprised of ethylcellulose.
Claim 8
Dependent Claim
65 words
A pharmaceutical preparation comprising sulfonic acid cationic exchange resin particles having a pharmacologically active monobasic drug adsorbed thereon to form drug-resin complex particles, which resin particles have been treated with from about 15 to about 25 percent by weight of glycerin, based on the combined weight of the glycerin and the complex particles, and subsequently individually coated with a water-permeable diffusion barrier comprised of ethylcellulose.
Claim 9
Dependent Claim
26 words
A pharmaceutical preparation as in claim 5 wherein the resin particles have been treated with from about 17.5 to about 25 percent by weight of glycerin.
Claim 10
Dependent Claim
12 words
A pharmaceutical preparation as in claim 6 wherein the drug is phenylpropanolamine.
Claim 11
Dependent Claim
18 words
A pharmaceutical preparation as in claim 6 wherein the resin is gel-type divinylbenzene sulfonic acid cationic exchange resin.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-10 | 1993-01-09 | 1993-07-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-10 | 1997-01-09 | 1997-07-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-10 | 2001-01-09 | 2001-07-11 | $7700.00 | Window Closed / Lapsed |