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US4842598A Expired / Lapsed US ⏱️ 0.0 years remaining

Therapeutic agent delivery system and method

Assignee: Controlled Release Technologies Inc
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Filing: 1987-12-24
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Granted: 1989-06-27
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Expires: 2007-12-24
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Abstract

Abstract A method and apparatus for controllably administering a therapeutic agent to a patient is disclosed. The method and apparatus uses an electromotive force between an anode and a cathode to cause the therapeutic agent to migrate through a semipermeable membrane. The therapeutic agent is then delivered to the patient.

Inventors

  • 👤 Loi H. Tran

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 09:15
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 85 words
A therapeutic agent delivery system comprising: a housing retaining a semipermeable membrane and together with the membrane defining a donor chamber adapted to hold the therapeutic agent, the membrane being made of a material that is substantially impermeable to the therapeutic agent in an ionic form; an anode and a cathode exposed within the donor chamber such that an electromotive force between the anode and the cathode will alter the electrical charge of the therapeutic agent to permit the agent to pass through the membrane.
Claim 2
Dependent Claim 85 words
A therapeutic agent delivery system comprising: a housing retaining a semipermeable membrane and together with the membrane defining a donor chamber adapted to hold the therapeutic agent, the membrane being made of a material that is substantially impermeable to the therapeutic agent in an ionic form; an anode and a cathode exposed within the donor chamber such that an electromotive force between the anode and the cathode will alter the electrical charge of the therapeutic agent to permit the agent to pass through the membrane.
Claim 3
Dependent Claim 17 words
The therapeutic agent delivery system of claim 1 including power source means for generating the electromotive force.
Claim 4
Dependent Claim 23 words
The therapeutic agent delivery system of claim 2 including control means for controlling the electromotive force generated by power source means over time.
Claim 5
Dependent Claim 19 words
The therapeutic agent delivery system of claim 3 wherein the system is adapted for implantation in a living body.
Claim 6
Dependent Claim 17 words
The therapeutic agent delivery system of claim 1 wherein the membrane is made of a hydrophobic material.
Claim 7
Dependent Claim 20 words
The therapeutic agent delivery system of claim 1 including a therapeutic agent received in the chamber in its ionic form.

References Cited (Backward Citations)

US4140121A Cited
US4436094A Cited
US4639244A Cited
US4540403A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-06-26 1992-12-26 1993-06-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-06-26 1996-12-26 1997-06-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-06-26 2000-12-26 2001-06-27 $7700.00 Window Closed / Lapsed

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