US4840174A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of laser treatment of cancerization of the oral cavity
Assignee: University of Cincinnati
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Filing: 1987-12-22
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Granted: 1989-06-20
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Expires: 2007-12-22
Abstract
Abstract Cancer of the oral cavity is treated by sensitizing malignant and premalignant tissue and non-selectively irradiating the entire oral cavity with a destructive laser. The strength or intensity of the light is adjusted so that nonsensitized tissue is not damaged. A special holder adapted to permit irradiation of the entire oral cavity from two fiber optic diffusers is also disclosed.
Inventors
- 👤 Jack L. Gluckman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 02:01
CPC Classifications
A; A61; A61C; A61C1/00; A61C1/0046; A61B; A61B17/00; A61B17/24; A61N; A61N5/00; A61N5/06; A61N5/0601; A61N5/0603; A61N5/067; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B2018/2255; A61B2018/2261; A61N2005/0606; A61N2005/0635; A61N2005/0643; A61N2005/0645; A61N2005/0647
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
65 words
A method of treating field cancerization of the oral cavity comprising sensitizing premalignant and malignant tissue to a destructive light; non-selectively irradiating substantially all of the oral cavity with said destructive light by emitting said destructive light through at least one optical diffuser positioned within said oral cavity said destructive light being of an intensity and duration effective to damage said premalignant and malignant tissue.
Claim 2
Independent Claim
65 words
A method of treating field cancerization of the oral cavity comprising sensitizing premalignant and malignant tissue to a destructive light; non-selectively irradiating substantially all of the oral cavity with said destructive light by emitting said destructive light through at least one optical diffuser positioned within said oral cavity said destructive light being of an intensity and duration effective to damage said premalignant and malignant tissue.
Claim 3
Dependent Claim
24 words
The method claimed in claim 1 wherein substantially all of said oral cavity is radiated at one time from at least one light source.
Claim 4
Dependent Claim
22 words
The method claimed in claim 1 wherein said oral cavity is irradiated by light emitted from a laser through said optical diffuser.
Claim 5
Dependent Claim
18 words
The method claimed in claim 3 wherein said light is emitted through a plurality of fiber optic diffusers.
Claim 6
Dependent Claim
16 words
The method claimed in claim 4 wherein said light is emitted from two fiber optic diffusers.
Claim 7
Dependent Claim
56 words
The method claimed in claim 5 comprising positioning a first fiber optic diffuser parallel to an axis from a first premolar to a second premolar on the left portion of the oral cavity and a second diffuser on an axis from a first premolar to a second molar on the right portion of said oral cavity.
Claim 8
Dependent Claim
24 words
The method claimed in claim 5 wherein said two fiber optic diffusers are held in position by a holder transparent to said laser light.
Claim 9
Dependent Claim
16 words
The method claimed in claim 4 wherein said light has a wavelength of about 630 nM.
Claim 10
Dependent Claim
22 words
The method claimed in claim 4 wherein said oral cavity is radiated with light providing less than about 50 Joules/cm 2 .
Claim 11
Dependent Claim
20 words
The method claimed in claim 9 wherein said oral cavity is radiated with light providing about 20-30 Joules/cm 2 .
Claim 12
Dependent Claim
32 words
The method claimed in claim 1 further comprising blocking at least a portion of said oral cavity from said destructive light to prevent heat destruction of said portion of said oral cavity.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-06-19 | 1992-12-19 | 1993-06-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-06-19 | 1996-12-19 | 1997-06-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-06-19 | 2000-12-19 | 2001-06-20 | $7700.00 | Window Closed / Lapsed |