US4834101A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Catheter-type electrochemical sensors
Assignee: BOARD OF REGENTS ACTING FOR AND ON BEHALF OF UNIVERSITY OF MICHIGAN A CORP OF MI
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Filing: 1987-06-26
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Granted: 1989-05-30
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Expires: 2007-06-26
Abstract
Abstract A dual lumen CO 2 catheter is formed of medical grade dual lumen silicone rubber tubing which has been impregnated with tridodecyl amine. The silicone tubing is gas permeable, and an external reference electrode is used to monitor the potential across the impregnated outer wall of the dual lumen tubing as a function of pH. The analyte to be monitored is selected from the group consisting of CO 2 , NH 3 , SO 2 , NO 2 , H 2 S, and HCN, the internal reference and electrolyte solutions contained in the lumens being selected in response to the particular analyte desired to be monitored. In a CO 2 embodiment, the reference lumen is filled with a buffered internal reference solution, and the response lumen is filled with a bicarbonate filling solution. Reference wires formed of Ag/AgCl in respective ones of the lumens forms the internal electrodes.
Inventors
- 👤 Michael E. Collison
- 👤 Mark E. Meyerhoff
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 06:27
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14542; A61B5/14539; A61B5/1468; A61B5/1473; G; G01; G01N; G01N27/00; G01N27/26; G01N27/403; G01N27/4035
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
182 words
An arrangement for monitoring concentration of an analyte selected from the group consisting of CO 2 , NH 3 , SO 2 , NO 2 , H 2 S, and HCN, the arrangement comprising: elongated body means having dual lumens separated from one another by an integrally formed interlumen wall, said elongated body means being formed of a gas-permeable polymeric material impregnated with a pH sensitive material over at least a portion thereof for forming a pH responsive membrane, said elongated body means having a first one of said dual lumens therein accommodating an electrolyte solution responsive to a selected one of the analytes, a second one of said dual lumens accommodating a reference solution, and an ion sensitive membrane arranged as said integrally formed interlumen wall between said first and second ones of said dual lumens; and first and second sensor electrode means arranged in respective ones of said first and second ones of said dual lumens of said elongated body means for communicating electrically with respective ones of said electrolyte solution and said reference solution for detecting an electric potential.
Claim 2
Dependent Claim
182 words
An arrangement for monitoring concentration of an analyte selected from the group consisting of CO 2 , NH 3 , SO 2 , NO 2 , H 2 S, and HCN, the arrangement comprising: elongated body means having dual lumens separated from one another by an integrally formed interlumen wall, said elongated body means being formed of a gas-permeable polymeric material impregnated with a pH sensitive material over at least a portion thereof for forming a pH responsive membrane, said elongated body means having a first one of said dual lumens therein accommodating an electrolyte solution responsive to a selected one of the analytes, a second one of said dual lumens accommodating a reference solution, and an ion sensitive membrane arranged as said integrally formed interlumen wall between said first and second ones of said dual lumens; and first and second sensor electrode means arranged in respective ones of said first and second ones of said dual lumens of said elongated body means for communicating electrically with respective ones of said electrolyte solution and said reference solution for detecting an electric potential.
Claim 3
Dependent Claim
13 words
The arrangement of claim 1 wherein said pH sensitive material is tridodecyl amine.
Claim 4
Dependent Claim
13 words
The arrangement of claim 1 wherein said polymeric material is a silicone rubber.
Claim 5
Dependent Claim
17 words
The arrangement of claim 1 wherein said first and second sensor electrode means are formed of Ag/AgCl.
Claim 6
Dependent Claim
21 words
The arrangement of claim 1 wherein and electrolyte solution further comprises a bicarbonate solution, comprising 0.025M NaHCO 3 and 0.1M NaCl.
Claim 7
Dependent Claim
130 words
An arrangement for monitoring continuously in vivo concentration of blood gases, the arrangement comprising: elongated body means formed of a gas-permeable polymeric material impregnated with a pH sensitive material over a predetermined portion thereof for forming a pH responsive membrane, said elongated body means having first and second lumens therein accommodating respective ones of a buffered internal reference solution and a bicarbonate filling solution, said first and second lumens being an ion communication with one another via an integrally formed gas permeable membrane interposed therebetween; and first and second sensor electrode means arranged in respective ones of said first and second lumens of said elongated body means for communicating electrically with respective ones of said buffered internal reference and said bicarbonate filling solutions for detecting at least one electric potential.
Claim 8
Dependent Claim
130 words
An arrangement for monitoring continuously in vivo concentration of blood gases, the arrangement comprising: elongated body means formed of a gas-permeable polymeric material impregnated with a pH sensitive material over a predetermined portion thereof for forming a pH responsive membrane, said elongated body means having first and second lumens therein accommodating respective ones of a buffered internal reference solution and a bicarbonate filling solution, said first and second lumens being an ion communication with one another via an integrally formed gas permeable membrane interposed therebetween; and first and second sensor electrode means arranged in respective ones of said first and second lumens of said elongated body means for communicating electrically with respective ones of said buffered internal reference and said bicarbonate filling solutions for detecting at least one electric potential.
Claim 9
Dependent Claim
17 words
The arrangement of claim 6 wherein said first and second sensor electrode means are formed of Ag/AgCl.
Claim 10
Dependent Claim
22 words
The arrangement of claim 6 wherein said gas permeable polymeric material of which said elongated body means is formed is silicone rubber.
Claim 11
Dependent Claim
13 words
The arrangement of claim 6 wherein said pH sensitive material is tridodecyl amine.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-29 | 1992-11-28 | 1993-05-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-29 | 1996-11-28 | 1997-05-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-29 | 2000-11-28 | 2001-05-30 | $7700.00 | Window Closed / Lapsed |