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US4197853A Expired / Lapsed US ⏱️ 0.0 years remaining

PO2 /PCO2 sensor

Assignee: TGC RESEARCH Ltd
•
Filing: 1978-07-20
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Granted: 1980-04-15
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Expires: 1998-07-20
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Abstract

Abstract This invention relates to an electrochemical sensor system for the simultaneous and continuous measurement of the partial pressure of oxygen PO 2 and carbon dioxide partial pressure PCO 2 in fluids. The electrochemical sensor of the present invention is particularly useful for intra-arterial measuring PCO 2 and PO 2 in blood and is readily adapted to transcutaneous measurement of these blood gases by the addition of a heating element and minor configurational changes.

Inventors

  • 👤 Dawood Parker

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 20:44
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/403; G01N27/404; A; A61; A61B; A61B5/00; A61B5/145; A61B5/14539; A61B5/1491; G01N27/4045; G01N27/416; G01N27/4162

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 167 words
An electrochemical sensor for the simultaneous and continuous measurements of PO 2 and PCO 2 in fluids which comprises: (a) an electrode chamber having within; a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen. a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship. an electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from fluid to be tested, said membrane holding the electrolyte in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte; and said membrane being also permeable to water when the electrolyte is solid.
Claim 2
Dependent Claim 167 words
An electrochemical sensor for the simultaneous and continuous measurements of PO 2 and PCO 2 in fluids which comprises: (a) an electrode chamber having within; a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen. a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship. an electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from fluid to be tested, said membrane holding the electrolyte in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte; and said membrane being also permeable to water when the electrolyte is solid.
Claim 3
Dependent Claim 157 words
An electrochemical sensor for the simultaneous and continuous measurements of PO 2 and PCO 2 in fluids which comprises (a) an electrode chamber having within: a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen, a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship, a solid electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to water, oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from fluid to be tested, said membrane holding the electrolyte within in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte.
Claim 4
Dependent Claim 157 words
An electrochemical sensor for the simultaneous and continuous measurements of PO 2 and PCO 2 in fluids which comprises (a) an electrode chamber having within: a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen, a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship, a solid electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to water, oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from fluid to be tested, said membrane holding the electrolyte within in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte.
Claim 5
Dependent Claim 183 words
An electrochemical sensor for the simultaneous and continuous transcutaneous measurements of PO 2 and PCO 2 through animal skin which comprises: (a) an electrode chamber having within; a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen, a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship, an electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from the animal skin to be tested, said membrane holding the electrolyte in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte and (c) a controlled heating element associate with the electrode chamber for heating the animal skin in contact with or in proximity to the membrane.
Claim 6
Dependent Claim 183 words
An electrochemical sensor for the simultaneous and continuous transcutaneous measurements of PO 2 and PCO 2 through animal skin which comprises: (a) an electrode chamber having within; a first electrode responsive to pH changes produced by the presence of carbon dioxide, a second electrode capable of electrochemically reducing oxygen, a reference electrode for each of or common to the first and second electrodes, means for holding first electrode, second electrode and reference electrode in spaced apart, insulated relationship, an electrolyte in contact with the reference electrode and first and second electrodes; (b) a membrane permeable to oxygen and carbon dioxide having a first and second side, the first side being in contact with the electrolyte and the second side available for exposure to carbon dioxide and oxygen gases from the animal skin to be tested, said membrane holding the electrolyte in contact with the electrodes and providing for entry of oxygen and carbon dioxide gas into the electrolyte and (c) a controlled heating element associate with the electrode chamber for heating the animal skin in contact with or in proximity to the membrane.
Claim 7
Dependent Claim 17 words
An electrochemical sensor, according to claim 1, 2 or 3 wherein the electrolyte is an alkaline electrolyte.
Claim 8
Dependent Claim 42 words
An electrochemical sensor, according to claim 1, 2 or 3 in combination with means for simultaneously measuring electrical changes produced by carbon dioxide between the first electrode and the reference electrode and by oxygen between the second electrode and the reference electrode.
Claim 9
Dependent Claim 18 words
An electrochemical sensor, according to claims 1, 2 or 3 wherein the first electrode is pH glass electrode.
Claim 10
Dependent Claim 17 words
An electrochemical sensor, according to 1, 2 or 3 wherein the second electrode is silver or platinum.
Claim 11
Dependent Claim 17 words
An electrochemical sensor, according to 1, 2 or 3 wherein the second electrode is silver or platinum.
Claim 12
Dependent Claim 19 words
An electrochemical sensor, according to claims 1, 2 or 3 wherein the reference electrode is made from silver/silver chloride.
Claim 13
Dependent Claim 17 words
An electrochemical sensor, according to claims 1, 2 or 3 wherein the membrane is made of polystyrene.
Claim 14
Dependent Claim 25 words
An electrochemical sensor, according to claim 2, mounted in the tip of an intra-arterial catheter for measurement of PO 2 and PCO 2 in blood.

References Cited (Backward Citations)

US3659586A Cited
US3795239A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-04-15 1983-10-15 1984-04-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-04-15 1987-10-15 1988-04-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-04-15 1991-10-15 1992-04-15 $7700.00 Window Closed / Lapsed

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