US4828386A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multiwell plates containing membrane inserts
Assignee: Pall Corp
•
Filing: 1987-06-19
•
Granted: 1989-05-09
•
Expires: 2007-06-19
Abstract
Abstract A multiwell plate suitable for use in a spectrometer which uses a vertical beam of light comprising a first plate having a plurality of wells for receiving sample, wherein the wells have transparent bottom surfaces to allow for the transmission of a vertical beam of light, and a unitary insert comprising a biochemically compatible microporous surface capable of binding biological materials shaped to fit into at least one well of the plate without interfering with the vertical beam of light.
Inventors
- 👤 Vlado I. Matkovich
- 👤 Peter J. Degen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 05:25
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; G01N21/00; G01N21/01; G01N21/03; G01N33/5302; G01N33/5304; B; B01; B01L; B01L2200/00; B01L2200/16; G01N2021/0325; G01N2021/0346; G01N2201/00; G01N2201/04; G01N2201/0446; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/809
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
102 words
A multiwell plate suitable for use in a spectrophotometer which uses a vertical beam of light comprising: a first plate having a plurality of wells for receiving sample, wherein said wells have transparent bottom surfaces to allow for the transmission of a vertical beam of light; a unitary insert comprising a biochemically compatible microporous binding surface shaped to fit into at least one well of said plate without interfering with said vertical beam of light so as to provide a free light path through said well, said free light path passing through said sample when said sample is present in said well.
Claim 2
Dependent Claim
102 words
A multiwell plate suitable for use in a spectrophotometer which uses a vertical beam of light comprising: a first plate having a plurality of wells for receiving sample, wherein said wells have transparent bottom surfaces to allow for the transmission of a vertical beam of light; a unitary insert comprising a biochemically compatible microporous binding surface shaped to fit into at least one well of said plate without interfering with said vertical beam of light so as to provide a free light path through said well, said free light path passing through said sample when said sample is present in said well.
Claim 3
Dependent Claim
36 words
The multiwell plate of claim 1, wherein said insert comprises a second plate arranged to fit over said first plate and having one or more projections which fit into said one or more of said wells.
Claim 4
Dependent Claim
18 words
The multiwell plate of claim 2, wherein said projections comprise hollow cylinders with open top and bottom surfaces.
Claim 5
Dependent Claim
28 words
The multiwell plate of claim 2, wherein said projections comprise cylinders with a top or bottom surface through which said beam of light is transmitted substantially without loss.
Claim 6
Dependent Claim
11 words
The multiwell plate of claim 2, wherein said insert is removable.
Claim 7
Dependent Claim
24 words
The multiwell plate of claim 2, wherein said second plate locks to said first plate when said projection is fully inserted into said well.
Claim 8
Dependent Claim
22 words
The multiwell plate of claim 2, wherein said insert comprises a sufficient number of projections to fit into all of said wells.
Claim 9
Dependent Claim
19 words
The multiwell plate of claim 2, wherein said insert comprises a single projection which fits into a single well.
Claim 10
Dependent Claim
14 words
The multiwell plate of claim 1, wherein said insert fits completely within said well.
Claim 11
Dependent Claim
22 words
The multiwell plate of claim 9, wherein said insert comprises a sheet of microporous material longer than the diameter of said well.
Claim 12
Dependent Claim
31 words
The multiwell plate of claim 10, wherein said sheet is substantially equal in length to the circumference of said well and said sheet fits against the vertical walls of said well.
Claim 13
Dependent Claim
19 words
The multiwell plate of claim 9, wherein said insert comprises a hollow polyhedron without a top or bottom surface.
Claim 14
Dependent Claim
13 words
The multiwell plate of claim 12, wherein said polyhedron is a triangular prism.
Claim 15
Dependent Claim
17 words
The multiwell plate of claim 9 wherein said insert fits within the bottom two-thirds of said well.
Claim 16
Dependent Claim
37 words
The multiwell plate of claim 14, wherein said well comprises substantially vertical walls and said vertical walls comprise an inward projection above the height of said insert, whereby said insert is locked into position in said well.
Claim 17
Dependent Claim
18 words
The multiwell plate of claim 9, wherein said microporous surface comprises polyamide affixed to a flexible backing sheet.
Claim 18
Dependent Claim
12 words
The multiwell plate of claim 16, wherein said backing sheet is resilient.
Claim 19
Dependent Claim
15 words
The multiwell plate of claim 9, wherein said insert is irremovably attached to said well.
Claim 20
Dependent Claim
15 words
The multiwell plate of claim 9, wherein said insert is removably located within said well.
Claim 21
Dependent Claim
12 words
The multiwell plate of claim 1, wherein said microporous surface comprises polyamide.
References Cited (Backward Citations)
US3027799A
Cited
US4146365A
Cited
US4290997A
Cited
US4629563A
Cited
US4629563B1
Cited
US4357142A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-08 | 1992-11-07 | 1993-05-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-08 | 1996-11-07 | 1997-05-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-08 | 2000-11-07 | 2001-05-09 | $7700.00 | Window Closed / Lapsed |