Beta-blocking oxindole derivatives

Claim 1

An oxindole compound of the formula: ##STR14## wherein R 1 is a C 2 -C 10 -nitratoalkyl, X is hydrogen or C 1 -C 6 -alkyl; Y, together with X and the carbon atom to which they are attached, forms a C 3 -C 7 cycloalkyl ring, or is a group of the formula: ##STR15## wherein R 2 is hydrogen or R 2 together with X represents a valency bond, R 3 is hydrogen or a straight-chained or branched C 1 -C 6 -alkyl and R 4 is straight-chained or branched C 1 -C 6 -alkyl, C 3 -C 6 cycloalkyl; or phenyl, furan, thiophene, pyrrole, pyrazole, imidazole, triazole, tetrazole, imidazolinone, pyridine, pyrimidine, uracil, indole, indazole and dihydropyran radical which is unsubstituted or substituted by halogen, C 1 -C 6 -alkyl, hydroxyalkyl, hydroxyl, C 1 -C 6 -alkoxy, C 2 -C 4 -alkenyl, C 2 -C 4 -alkenyloxy, C 2 -C 4 -alkynyl, amino, C 1 -C 4 -alkylamino, C 2 -C 8 -dialkylamino, aminocarbonyl, C 1 -C 4 -alkylaminocarbonyl, C 2 -C 8 -dialkylaminocarbonyl, cyano, C 2 -C 4 -alkanoyl, aminosulphonyl, C 1 -C 4 -alkylaminosulphonyl, C 2 -C 8 -dialkylaminosulphonyl, carboxyl, C 1 -C 6 -alkoxycarbonyl, C 1 -C 6 -alkylthio, C 1 -C 6 -alkylsulphinyl, C 1 -C 6 -alkylsulphonyl, C 2 -C 4 -alkanoylamido, C 1 -C 4 -alkylsulphonylamido or nitro groups or a C 1 -C 2 -alkylenedioxy radical or R 3 and R 4 together with the C-atom represent pyrrolidine or piperidine; or a pharmacologically acceptable salt thereof.