US4826675A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anticalculus oral composition
Assignee: Colgate Palmolive Co
•
Filing: 1988-02-17
•
Granted: 1989-05-02
•
Expires: 2008-02-17
Abstract
Abstract An Anticalculus Oral Composition, typically a mouthwash or dentifrice gel, containing compound having C-O-P bonds, such as phytic acid or an alkali metal (including ammonium) salt thereof as anticalculus agent, homogeneously distributed in a dentally acceptable oral vehicle. Also, present to inhibit enzymatic hydrolysis of the phytic compound and to promote caries reduction is an alkali metal fluoride.
Inventors
- 👤 Abdul Gaffar
- 👤 Shek-Hong Lau
- 👤 John Afflitto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 19:52
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/30; A61K8/55
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
113 words
An anticalculus oral composition consisting essentially of a dentally acceptable oral vehicle and homogeneously distributed therein about 0.1-7% by weight of a compound having C--O--P bonds selected from the group consisting of phytic acid, myo-inositol tetrakis dihydrogen phosphate, myo-inositol trikis dihydrogen phosphate, phosphoglyceric acid, phosphoenol pyruvic acid and alkali metal salt thereof as inhibitor of hydroxyapatite formation and about 0.02-2.2% by weight of an alkali metal fluoride as inhibitor of enzymatic hydrolysis and also anti-caries agent, said alkali metal fluoride being the sole anti-caries agent which provides fluoride to the oral composition, said oral composition containing no compounds which provide polyvalent cations capable of forming a complex with said inhibitor of hydroxyapatite formation.
Claim 2
Dependent Claim
113 words
An anticalculus oral composition consisting essentially of a dentally acceptable oral vehicle and homogeneously distributed therein about 0.1-7% by weight of a compound having C--O--P bonds selected from the group consisting of phytic acid, myo-inositol tetrakis dihydrogen phosphate, myo-inositol trikis dihydrogen phosphate, phosphoglyceric acid, phosphoenol pyruvic acid and alkali metal salt thereof as inhibitor of hydroxyapatite formation and about 0.02-2.2% by weight of an alkali metal fluoride as inhibitor of enzymatic hydrolysis and also anti-caries agent, said alkali metal fluoride being the sole anti-caries agent which provides fluoride to the oral composition, said oral composition containing no compounds which provide polyvalent cations capable of forming a complex with said inhibitor of hydroxyapatite formation.
Claim 3
Dependent Claim
23 words
The anticalculus oral composition claimed in claim 1 wherein said compound having C--O--P bonds is phytic acid or an alkali metal salt thereof.
Claim 4
Dependent Claim
16 words
The anticalculus oral composition claimed in claim 1 wherein said alkali metal fluoride is sodium fluoride.
Claim 5
Dependent Claim
16 words
The anticalculus oral composition claimed in claim 2 wherein said alkali metal fluoride is sodium fluoride.
Claim 6
Dependent Claim
36 words
The anticalculus oral composition claimed in claim 1 wherein said dentally acceptable oral vehicle contains water and humectant collectively in amount of about 10-90% by weight and about 5-50% by weight of a siliceous polishing agent.
Claim 7
Dependent Claim
30 words
The anticalculus oral composition claimed in claim 5 wherein said compound having C--O--P bonds is phytic acid or the sodium salt thereof and said alkali metal fluoride is sodium fluoride.
Claim 8
Dependent Claim
39 words
The anticalculus oral composition claimed in claim 1 wherein said dentally acceptable oral vehicle contains about 70-99.99% by weight of water-non-toxic alcohol mixture and the weight ratio of water to non-toxic alcohol is from about 1:1 to about 20:1.
Claim 9
Dependent Claim
36 words
The anticalculus oral composition claimed in claim 7 wherein said compound having C--O--P bonds is phytic acid or the sodium salt thereof, said alkali metal fluoride is sodium fluoride and said non-toxic alcohol is ethyl alcohol.
Claim 10
Independent Claim
133 words
A method of inhibiting dental calculus comprising applying to teeth a calculus-inhibiting amount of an anticalculus oral composition having a pH of about 4.5 to about 9 consisting essentially of a dentally acceptable oral vehicle and homogeneously distributed therein about 0.1-7% by weight of a compound having C--O--P bonds selected from the group consisting of phytic acid myo-inositol tetrakis (dihydrogen phosphate), myo-inositol trikis (dihydrogen phosphate), phosphoglyceric acid, phosphenol pyruvic acid and alkali metal salt thereof as inhibitor of enzymatic hydrolysis and also anti-caries agent, said alkali metal fluoride being the sole anti-caries agent which provides fluoride to the oral composition, said oral composition containing no compounds which provide polyvalent cations capable of forming a complex with said inhibitor of hydroxyapatite formation, said composition when being so applied being effective to inhibit dental calculus.
Claim 11
Independent Claim
133 words
A method of inhibiting dental calculus comprising applying to teeth a calculus-inhibiting amount of an anticalculus oral composition having a pH of about 4.5 to about 9 consisting essentially of a dentally acceptable oral vehicle and homogeneously distributed therein about 0.1-7% by weight of a compound having C--O--P bonds selected from the group consisting of phytic acid myo-inositol tetrakis (dihydrogen phosphate), myo-inositol trikis (dihydrogen phosphate), phosphoglyceric acid, phosphenol pyruvic acid and alkali metal salt thereof as inhibitor of enzymatic hydrolysis and also anti-caries agent, said alkali metal fluoride being the sole anti-caries agent which provides fluoride to the oral composition, said oral composition containing no compounds which provide polyvalent cations capable of forming a complex with said inhibitor of hydroxyapatite formation, said composition when being so applied being effective to inhibit dental calculus.
References Cited (Backward Citations)
US3934002A
Cited
US4263276A
Cited
US4305928A
Cited
US4259316A
Cited
US4335102A
Cited
US4528181A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-01 | 1992-10-31 | 1993-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-01 | 1996-10-31 | 1997-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-01 | 2000-10-31 | 2001-05-02 | $7700.00 | Window Closed / Lapsed |