Patent EP0108520A2 successfully refreshed from Google Patents.
Patent US4825162A successfully refreshed from Google Patents.
US4825162A
Expired / Lapsed
US
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Nuclear magnetic resonance (NMR) imaging with multiple surface coils
Assignee: General Electric Co
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Filing: 1987-12-07
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Granted: 1989-04-25
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Expires: 2007-12-07
Abstract
Abstract A method for simultaneously receiving a different NMR response signal from each of a plurality of closely-spaced surface coils, first provides an array of a plurality of the surface coils, each positioned so as to have substantially no interaction with all adjacent surface coils. A different NMR response signal is received from an associated portion of the sample enclosed within an imaging volume defined by the array. Each different NMR response signal is used to construct a different one of a like plurality of NMR images of the sample, with the plurality of different images then being combined, on a point-by-point basis, to produce a single composite NMR image of a total sample portion from which NMR response signal contribution was received by any of the array of surface coils. Interactions between non-adjacent surface coils are minimized by coupling each onto an associated preamplifier.
Inventors
- 👤 Bernard Roemer
- 👤 William A. Edelstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 06:07
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; G01R33/32; G01R33/34; G01R33/341; G01R33/3415
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
198 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, with each surface coil being a single-turn surface coil substantially identical to any other surface coil of the array and with each surface coil being closely-spaced to and having overlapping fields-of-view with, but having substantially no interaction with, at least all adjacent surface coils; (b) substantially simultaneously receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point basis, to produce a signal final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 2
Independent Claim
198 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, with each surface coil being a single-turn surface coil substantially identical to any other surface coil of the array and with each surface coil being closely-spaced to and having overlapping fields-of-view with, but having substantially no interaction with, at least all adjacent surface coils; (b) substantially simultaneously receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point basis, to produce a signal final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 3
Independent Claim
197 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, and with each surface coil having substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) the combining the plurality N of different images with weighting, on a point-by-point basis, each pixel of each image by a factor determined by at least by magnitude of correlated and uncorrelated noise between each adjacent pair of surface coils to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 4
Independent Claim
197 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, and with each surface coil having substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) the combining the plurality N of different images with weighting, on a point-by-point basis, each pixel of each image by a factor determined by at least by magnitude of correlated and uncorrelated noise between each adjacent pair of surface coils to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 5
Dependent Claim
40 words
The method of claim 2, wherein step (d) further includes the step of also weighting each pixel of each image by a factor determined by the position of that pixel in at least one of the final and different images.
Claim 6
Independent Claim
204 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced, substantially-circular-shaped RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, and positioning the centers of any pair of adjacent surface coils at a separation distance substantially equal to one and one-half times the radius of one of the surface coils of the pair to cause each surface coil to have substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point basis, to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 7
Independent Claim
204 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced, substantially-circular-shaped RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality N of surface coils, with the array defining an imaging volume, and positioning the centers of any pair of adjacent surface coils at a separation distance substantially equal to one and one-half times the radius of one of the surface coils of the pair to cause each surface coil to have substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point basis, to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 8
Dependent Claim
42 words
The method of claim 4, further comprising the steps of: arranging the array on a surface; and positioning the center of each different surface coil, in a group of three adjacent surface coils, substantially at a different apex of an equilateral triangle.
Claim 9
Dependent Claim
19 words
The method of claim 5, further comprising the step of arranging the surface to extend only in two dimensions.
Claim 10
Independent Claim
201 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced, substantially-square-shaped RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality of surface coils, with the array defining an imaging volume, and positioning the centers of any pair of adjacent surface coils at a separation distance of about nine-tenths of the side length of one of the surface coils of the pair to cause each surface coil to have substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) the combining the plurality N of different images, on a point-by-point basis, to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 11
Independent Claim
201 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced, substantially-square-shaped RF surface coils, comprising the steps of: (a) providing an at least one-dimensional array of the plurality of surface coils, with the array defining an imaging volume, and positioning the centers of any pair of adjacent surface coils at a separation distance of about nine-tenths of the side length of one of the surface coils of the pair to cause each surface coil to have substantially no interaction with at least all adjacent surface coils; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) the combining the plurality N of different images, on a point-by-point basis, to produce a single final NMR image of all sample portions from which a NMR response signal was received by any one of the surface coils.
Claim 12
Dependent Claim
30 words
The method of claim 7, further comprising the steps of: setting N=4, and linearly arranging the four surface coils with a total of about 3.7 times the common side length.
Claim 13
Dependent Claim
79 words
Apparatus for simultaneously receiving NMR response signals from nuclei within a predetermine portion of a sample, comprising: a plurality of substantially-identical single-turn surface coil antennae, each positioned to overlap at least a portion of at least one other surface coil and to simultaneously have substantially no interaction with at least all adjacent surface coils; and means for maintaining the positions of the surface coils in an array extending in at least one dimensional along a surface enclosing the sample.
Claim 14
Dependent Claim
79 words
Apparatus for simultaneously receiving NMR response signals from nuclei within a predetermine portion of a sample, comprising: a plurality of substantially-identical single-turn surface coil antennae, each positioned to overlap at least a portion of at least one other surface coil and to simultaneously have substantially no interaction with at least all adjacent surface coils; and means for maintaining the positions of the surface coils in an array extending in at least one dimensional along a surface enclosing the sample.
Claim 15
Dependent Claim
127 words
Apparatus for simultaneously receiving NMR response signals from nuclei within a predetermined portion of a sample, comprising: a plurality of surface coil antenna with a selected one of (1) a substantially-circular shape and (2) a substantially-square shape, positioned in an at least one-dimensional array and with each surface coil having substantially no interaction with at least all adjacent surface coils by positioning the centers of any pair of adjacent surface coils to be separated from each other by a distance of (1) about one and one-half times the radius of one of the surface coils of that pair, if substantially-circular coils are utilized, and (2) by about nine-tenths of the side length of one of the surface coils of that pair, if substantially square coils are utilized.
Claim 16
Dependent Claim
127 words
Apparatus for simultaneously receiving NMR response signals from nuclei within a predetermined portion of a sample, comprising: a plurality of surface coil antenna with a selected one of (1) a substantially-circular shape and (2) a substantially-square shape, positioned in an at least one-dimensional array and with each surface coil having substantially no interaction with at least all adjacent surface coils by positioning the centers of any pair of adjacent surface coils to be separated from each other by a distance of (1) about one and one-half times the radius of one of the surface coils of that pair, if substantially-circular coils are utilized, and (2) by about nine-tenths of the side length of one of the surface coils of that pair, if substantially square coils are utilized.
Claim 17
Dependent Claim
32 words
The apparatus of claim 10, wherein the substantially-square-shaped coils are utilized, N=4 and the four surface coils are linearly arranged with a total length of about 3.7 times the common side length.
Claim 18
Dependent Claim
37 words
The apparatus of claim 10, wherein the array includes at least one pair of surface coils not adjacent to each other; and further including means for minimizing the interaction between each non-adjacent surface coil of that pair.
Claim 19
Dependent Claim
61 words
The apparatus of claim 12, wherein said minimizing means comprises a plurality of preamplifiers, each having an input impedance on the order of 5 ohms at the NMR response frequency; a different preamplifier being connected to the output of each different one of the non-adjacent surface coils and providing minimized interaction signal, for that associated surface coil, from the preamplifier output.
Claim 20
Dependent Claim
31 words
The apparatus of claim 12, further comprising means, operating with each different preamplifier, for reducing the current circulating in the associated surface coil during reception, without substantially changing the signal-to-noise ratio.
Claim 21
Dependent Claim
39 words
The apparatus of claim 13, wherein the number of preamplifiers is equal to the number of surface coils in the array and the output of each different surface coil is connected to an input of a different, associated preamplifier.
Claim 22
Dependent Claim
35 words
The apparatus of claim 15, further comprising means for substantially simultaneously obtaining the signals at the outputs of all preamplifiers and for then providing the obtained signals in a predetermined serial order for subsequent use.
Claim 23
Independent Claim
271 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced RF surface coils, comprising the steps of: (a1) providing an at least one-dimensional array of the plurality N of surface coils with the array defining an imaging volume, and with each surface coil having substantially no interaction with at least all adjacent surface coils; (a2) and also providing in the array at least one pair of surface coils not adjacent to each other; and (a3) minimizing the interaction between each non-adjacent surface coil of that pair by: providing a preamplifier for each surface coil; connecting the output of each different one of the pair of non-adjacent surface coils to the input of a different preamplifier; and causing an effective input impedance of the preamplifier, at the associated surface coil, to resonate at the NMR response frequency with the output impedance of that surface coil and reduce the apparent surface coil Q towards a value of zero; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point bases, to produce a single final NMR image of all sample portions from whcih a NMR response signal was received by any one of the surface coils.
Claim 24
Independent Claim
271 words
A method for simultaneously receiving a different NMR response signal from each of a plurality N of closely-spaced RF surface coils, comprising the steps of: (a1) providing an at least one-dimensional array of the plurality N of surface coils with the array defining an imaging volume, and with each surface coil having substantially no interaction with at least all adjacent surface coils; (a2) and also providing in the array at least one pair of surface coils not adjacent to each other; and (a3) minimizing the interaction between each non-adjacent surface coil of that pair by: providing a preamplifier for each surface coil; connecting the output of each different one of the pair of non-adjacent surface coils to the input of a different preamplifier; and causing an effective input impedance of the preamplifier, at the associated surface coil, to resonate at the NMR response frequency with the output impedance of that surface coil and reduce the apparent surface coil Q towards a value of zero; (b) receiving at each different one of the plurality N of surface coils a different one of a like plurality N of NMR response signals each evoked from an associated portion of a sample enclosed in the imaging volume; (c) constructing each different one of a like plurality N of NMR images of a sample portion from the NMR response signals received by an associated surface coils; and (d) then combining the plurality N of different images, on a point-by-point bases, to produce a single final NMR image of all sample portions from whcih a NMR response signal was received by any one of the surface coils.
Claim 25
Dependent Claim
194 words
Apparatus for simultaneously receiving NMR response signals for nuclei within a predetermined portion of a sample, comprising: a plurality of surface coil antennae, positioned in an array extending in at least one dimension along a surface enclosing the sample, each surface coil positioned to have substantially no interaction with at least all adjacent surface coils, and with at least one pair of surface coils not adjacent to each other; and means for minimizing the interaction between each non-adjacent surface coil of each pair thereof, and including: a plurality of preamplifiers, each having an input impedance on the order of 5 ohms at the NMR response frequency, with a different preamplifier being connected to the output of each different one of the non-adjacent surface coils and providing a minimized-interaction signal, for that associated surface, from the preamplifier output; and means, operating with each different preamplifier, for providing an effective impedance connected in parallel with the associated surface coil to resonate at the NMR response frequency and reduce the apparatus surface coil Q towards the value of zero to reduce the current circulating in the associated surface coil during reception, without substantially changing the signal-to-noise ratio.
Claim 26
Dependent Claim
194 words
Apparatus for simultaneously receiving NMR response signals for nuclei within a predetermined portion of a sample, comprising: a plurality of surface coil antennae, positioned in an array extending in at least one dimension along a surface enclosing the sample, each surface coil positioned to have substantially no interaction with at least all adjacent surface coils, and with at least one pair of surface coils not adjacent to each other; and means for minimizing the interaction between each non-adjacent surface coil of each pair thereof, and including: a plurality of preamplifiers, each having an input impedance on the order of 5 ohms at the NMR response frequency, with a different preamplifier being connected to the output of each different one of the non-adjacent surface coils and providing a minimized-interaction signal, for that associated surface, from the preamplifier output; and means, operating with each different preamplifier, for providing an effective impedance connected in parallel with the associated surface coil to resonate at the NMR response frequency and reduce the apparatus surface coil Q towards the value of zero to reduce the current circulating in the associated surface coil during reception, without substantially changing the signal-to-noise ratio.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-24 | 1992-10-24 | 1993-04-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-24 | 1996-10-24 | 1997-04-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-24 | 2000-10-24 | 2001-04-25 | $7700.00 | Window Closed / Lapsed |