Patent US3440659A successfully refreshed from Google Patents.
Patent US4824950A successfully refreshed from Google Patents.
US4824950A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Chiral stationary phases and columns for chromatographic resolution
Assignee: Novartis Pharmaceuticals Corp
•
Filing: 1987-09-03
•
Granted: 1989-04-25
•
Expires: 2007-09-03
Abstract
Abstract This invention relates to chiral compositions.
Inventors
- 👤 Sandor Barcza
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:05
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/04; B; B01; B01J; B01J20/00; B01J20/28; B01J20/28002; B01J20/28004; B01J20/28054; B01J20/28057; B01J20/281; B01J20/286; B01J20/287; B01J20/29; B01J20/30; B01J20/3092; B01J20/32; B01J20/3202; B01J20/3204; B01J20/3214; B01J20/3217; B01J20/3219; B01J20/3231; B01J20/3242; B01J20/3244; B01J20/3246; B01J20/3257; B01J20/3259; B01J20/3261; B01J20/3263; C07D209/00; C07D209/02; C07D209/04; C07D209/30; C07D209/32; C07D209/34; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/36; C07D213/38; C07D215/00; C07D215/02; C07D215/16; C07D215/48; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/18; C07F7/1804; B01J2220/00; B01J2220/50; B01J2220/54; B01J2220/58
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
77 words
A composition of the formula, ##STR18## wherein A may be silica, alumina, glass beads, diatomaceous earth, or other siliceous solids; n represents an integer of from 1 to 3, R 3 and R 4 which can be the same or different each represents hydroxy, lower alkyl or alkoxy straight chain or branched having 1 to 4 carbon atoms, preferably unbranched, provided that when n=2 only R 3 occurs, when n=3 neither R 3 nor R 4 occurs;
Claim 2
Dependent Claim
77 words
A composition of the formula, ##STR18## wherein A may be silica, alumina, glass beads, diatomaceous earth, or other siliceous solids; n represents an integer of from 1 to 3, R 3 and R 4 which can be the same or different each represents hydroxy, lower alkyl or alkoxy straight chain or branched having 1 to 4 carbon atoms, preferably unbranched, provided that when n=2 only R 3 occurs, when n=3 neither R 3 nor R 4 occurs;
Claim 3
Dependent Claim
126 words
R 1 may be an aliphatic chain having 1 to 18 carbon atoms, phenylene, arylene or ether when R 1 may contain one --O--, with additionally at least two carbon alkylene group between the --O-- and the heteroatom which is part of the B unit; B may be --NR 5 SO 2 NR 5 --, --NR 5 CONR 5 --, --NR 5 CO--, or --CONR 5 -- or --SO 2 NR 5 --, --NR 5 SO 2 --, --COO--, --OOC--, --OCOO, NCOO--, OOCN--; where each R 5 may be independently H, or lower alkyl having 1 to 4 carbon atoms; and R 2 may be ##STR19## where R 6 may be lower alkyl having 1 to 4 carbon atoms, or benzyl; B-R 2 may be ##STR20##
Claim 4
Dependent Claim
126 words
R 1 may be an aliphatic chain having 1 to 18 carbon atoms, phenylene, arylene or ether when R 1 may contain one --O--, with additionally at least two carbon alkylene group between the --O-- and the heteroatom which is part of the B unit; B may be --NR 5 SO 2 NR 5 --, --NR 5 CONR 5 --, --NR 5 CO--, or --CONR 5 -- or --SO 2 NR 5 --, --NR 5 SO 2 --, --COO--, --OOC--, --OCOO, NCOO--, OOCN--; where each R 5 may be independently H, or lower alkyl having 1 to 4 carbon atoms; and R 2 may be ##STR19## where R 6 may be lower alkyl having 1 to 4 carbon atoms, or benzyl; B-R 2 may be ##STR20##
Claim 5
Dependent Claim
20 words
The composition according to claim 1 wherein R 3 and R 4 equal CH 3 , and n equals 1.
Claim 6
Dependent Claim
10 words
The composition according to claim 1 wherein n equals 3.
Claim 7
Dependent Claim
16 words
The composition according to claim 1 wherein 3 equals --NH 5 SO 2 NR 5 --.
Claim 8
Dependent Claim
11 words
The composition according to claim 1 wherein R 2 equals ##STR21##
Claim 9
Dependent Claim
16 words
The composition according to claim 1 wherein B equals --NR 5 CO--, or --CONR 5 --.
Claim 10
Dependent Claim
11 words
The composition according to claim 1 wherein R 5 equals H.
Claim 11
Dependent Claim
11 words
The composition according to claim 1 wherein R 2 equals ##STR22##
Claim 12
Dependent Claim
9 words
The composition of claim 1 which is 3-(Dehydroabietylaminosulfonylamino)propyldimethylsiloxy-derivatized silicagel.
Claim 13
Dependent Claim
13 words
The composition of claim 1 which is 3-(Dehydroabietylaminosulfonylamino)propyldimethylsiloxy-derivatized silicagel Alternate, Solid Phase Preparation.
Claim 14
Dependent Claim
13 words
The composition of claim 1 which is Covalently Bonded Chiral Aminoergolene Derivatized Silicagel.
Claim 15
Dependent Claim
13 words
The composition of claim 1 which is Chiral, Covalently Bonded Camphorsulfonamide Derivatized Silicagel.
Claim 16
Dependent Claim
14 words
The composition of claim 1 which is Chiral, Covalently Bonded Dehydroabetic Acid Derivatized Silicagel.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-24 | 1992-10-24 | 1993-04-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-24 | 1996-10-24 | 1997-04-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-24 | 2000-10-24 | 2001-04-25 | $7700.00 | Window Closed / Lapsed |