Patent US4822802A successfully refreshed from Google Patents.
US4822802A
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Method of fentanly administration for postoperative pain relief
Assignee: Alza Corp
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Filing: 1987-02-24
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Granted: 1989-04-18
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Expires: 2007-02-24
Abstract
Abstract A method of postoperative pain relief using transdermal delivery of fentanyl or its analgetically effective derivatives preceded by a dose of said material to increase the serum drug levels to steady state more quickly.
Inventors
- 👤 Gerhard Levy
- 👤 Mary Southam
- 👤 Marilou S. Powers Cramer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 04:19
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
122 words
A method for inducing and maintaining postoperative analgesia in a surgical patient which comprises: (a) administering to said patient a 100-300 μg dosage of a material selected from the group consisting of fentanyl, sufentanil, carfentanil, lofentanil and alfentanil, at the induction of anesthesia; and (b) placing a transdermal delivery device adapted to continuously transdermally administer a material selected from the group consisting of fentanyl, sufentanil, carfentanil, lofentanil and alfentanil, at an analgetically effective rate, on said patient no later than the induction of anesthesia; and (c) continuing the transdermal administration of said material at said rate by maintaining said device on said patient at least until said patient has recovered from anesthesia; wherein said material is administered internally and transdermally for analgesia.
Claim 2
Independent Claim
122 words
A method for inducing and maintaining postoperative analgesia in a surgical patient which comprises: (a) administering to said patient a 100-300 μg dosage of a material selected from the group consisting of fentanyl, sufentanil, carfentanil, lofentanil and alfentanil, at the induction of anesthesia; and (b) placing a transdermal delivery device adapted to continuously transdermally administer a material selected from the group consisting of fentanyl, sufentanil, carfentanil, lofentanil and alfentanil, at an analgetically effective rate, on said patient no later than the induction of anesthesia; and (c) continuing the transdermal administration of said material at said rate by maintaining said device on said patient at least until said patient has recovered from anesthesia; wherein said material is administered internally and transdermally for analgesia.
Claim 3
Dependent Claim
25 words
The method of claim 1 wherein said material is fentanyl and said analgetically effective rate is in the range of about 25 to 150 μg/hr.
Claim 4
Dependent Claim
21 words
The method of claim 2 wherein said dosage is about 100 μg and said analgetically effective rate is about 50 μg/hr.
Claim 5
Dependent Claim
21 words
The method of claim 2 wherein said dosage is about 100-200 μg and said analgetically effective rate is about 75 μg/hr.
Claim 6
Dependent Claim
21 words
The method of claim 2 wherein said dosage is about 200-300 μg and said analgetically effective rate is about 100 μg/hr.
Claim 7
Dependent Claim
16 words
The method of claim 1 wherein said placing step is simultaneous with the induction of anesthesia.
Claim 8
Dependent Claim
15 words
The method of claim 1 wherein said placing step is before the induction of anesthesia.
Claim 9
Dependent Claim
12 words
The method of claim 1 wherein said administering step is done intravenously.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-17 | 1992-10-17 | 1993-04-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-17 | 1996-10-17 | 1997-04-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-17 | 2000-10-17 | 2001-04-18 | $7700.00 | Window Closed / Lapsed |