Patent US4816582A successfully refreshed from Google Patents.
US4816582A
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Antimicrobial 2-oxo-1-azetidinesulphonic acids
Assignee: Hoffmann La Roche Inc
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Filing: 1987-10-22
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Granted: 1989-03-28
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Expires: 2007-10-22
Abstract
Abstract Antimicrobial 2-oxo-1-azetidinesulphonic acids of the formula <IMAGE> in which H2N <IMAGE> represents an amino-substituted thiazolyl group, R1 is lower alkyl which is substituted by carbamoyl, lower alkylsuphonyl, azido, piperidine-carbonyl, (hexahydro-1H-azepin-1-yl)carbonyl or lower alkynyl, and R2 is hydrogen or a lower organic group, typically, carbamoyloxymethyl.
Inventors
- 👤 Andre Furlenmeier
- 👤 Werner Hofheinz
- 👤 Christian N. Hubschwerlen
- 👤 Hans P. Isenring
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 18:24
CPC Classifications
C; C07; C07D; C07D277/00; C07D277/02; C07D277/20; A; A61; A61P; A61P31/00; A61P31/04; C07D205/00; C07D205/02; C07D205/06; C07D205/08; C07D205/085; C07D263/00; C07D263/02; C07D263/30; C07D263/34; C07D263/48; C07D403/00; C07D403/02; C07D403/12; C07D405/00; C07D405/02; C07D405/04; C07D413/00; C07D413/02; C07D413/12; C07D417/00; C07D417/02; C07D417/12; C07D417/14; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/0803; C07F7/081; C07F7/0812
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(carbamoylmethoxy)imino]acetamido]-4-[(E/Z-(methoxyimino)methyl]-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 2
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(carbamoylmethoxy)imino]acetamido]-4-[(E/Z-(methoxyimino)methyl]-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 3
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(2-propynyloxy)iminio]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 4
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(2-propynyloxy)iminio]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 5
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[2-(methylsulphonyl)ethoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 6
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[2-(methylsulphonyl)ethoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 7
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(2-azidoethoxy)imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in reacemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 8
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(2-azidoethoxy)imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in reacemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 9
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[(1-piperidinecarbonyl)methoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 10
Dependent Claim
21 words
3-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[(1-piperidinecarbonyl)methoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 11
Dependent Claim
21 words
5-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[[(hexahydro-1H-azepin-1-yl)carbonyl]methoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
Claim 12
Dependent Claim
21 words
5-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[[(hexahydro-1H-azepin-1-yl)carbonyl]methoxy]imino]acetamido]-4-carbamoyloxymethyl-2-oxo-1-azetidinesulphonic acid in racemic form or in the form of the 3S-enantiomer, as well as pharmaceutically compatible salts of these compounds.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-03-27 | 1992-09-26 | 1993-03-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-03-27 | 1996-09-26 | 1997-03-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-03-27 | 2000-09-26 | 2001-03-28 | $7700.00 | Window Closed / Lapsed |