US4816408A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Nozzle device in an apparatus for biochemical reactions
Assignee: Tosoh Corp
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Filing: 1987-05-21
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Granted: 1989-03-28
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Expires: 2007-05-21
Abstract
Abstract A nozzle device in an apparatus for biochemical reaction, including a biochemical reaction chamber, includes a nozzle having a tip and a porous filter fixed to the tip. The nozzle further includes an outer nozzle tube defining a first bore extending to the tip, a second bore extending through the porous filter and being coaxial with the first bore, an inner tube extending through the first bore to the tip and defining a third bore, the inner tube being tightly fitted into, and extending through, the second bore and having an outer diameter smaller than that of the inner diameter of the first bore to define an annular space in communication with the filter. The third bore is connected to a source of liquid and the annular space is connected with a source of suction, so that a liquid can be discharged to the reaction chamber from the first bore and sucked out of the reaction chamber through the filter.
Inventors
- 👤 Hideo Suzuki
- 👤 Shuji Iwasaki
- 👤 Satoru Kamada
- 👤 Yuji Higo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 09:23
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/02; B01L13/00; B01L13/02; B01L2200/00; B01L2200/02; B01L2300/00; B01L2300/04; B01L2300/041; B01L2300/044; B01L2400/00; B01L2400/04; B01L2400/0475; B01L2400/0487; B01L9/00; B01L9/52
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
188 words
A nozzle device in an apparatus for biochemical reactions, including a biochemical reaction chamber, comprising: a nozzle having a tip, means for delivery of a liquid to said tip and means for exhaust of a liquid from said tip; a porous filter fixed to said tip; and means for inserting said filter into said reaction chamber, wherein said nozzle comprises: an outer nozzle tube defining a first bore extending to said tip; a second bore extending through said porous filter and being coaxial with said first bore; an inner tube extending through said first bore to said tip and defining a third bore, said inner tube being tightly fitted into, and extending through said second bore and having an outer diameter smaller than an inner diameter of said first bore to define an annular space in communication with said filter; means for connecting said third bore of said inner tube with a source of liquid, whereby said third bore comprises said liquid delivery means; and means for connecting said annular space with a source of suction, whereby said filter and said annular space comprise said liquid exhaust means.
Claim 2
Dependent Claim
188 words
A nozzle device in an apparatus for biochemical reactions, including a biochemical reaction chamber, comprising: a nozzle having a tip, means for delivery of a liquid to said tip and means for exhaust of a liquid from said tip; a porous filter fixed to said tip; and means for inserting said filter into said reaction chamber, wherein said nozzle comprises: an outer nozzle tube defining a first bore extending to said tip; a second bore extending through said porous filter and being coaxial with said first bore; an inner tube extending through said first bore to said tip and defining a third bore, said inner tube being tightly fitted into, and extending through said second bore and having an outer diameter smaller than an inner diameter of said first bore to define an annular space in communication with said filter; means for connecting said third bore of said inner tube with a source of liquid, whereby said third bore comprises said liquid delivery means; and means for connecting said annular space with a source of suction, whereby said filter and said annular space comprise said liquid exhaust means.
Claim 3
Dependent Claim
26 words
The nozzle device of claim 1 including granular beads in said reaction chamber, said granular beads having surfaces capable of supporting an antigen-antibody reaction product complex.
Claim 4
Dependent Claim
41 words
The nozzle device of claim 1, wherein said nozzle device comprises a B/F separation means of said biochemical reaction apparatus, wherein said means for exhaust of a liquid comprise suction means capable of sucking a washing liquid from said reaction chamber.
Claim 5
Dependent Claim
19 words
The nozzle device of claim 1, wherein said filter has a flat surface at an end opposite said tip.
Claim 6
Dependent Claim
15 words
The nozzle device of claim 4, wherein said filter is formed of a rigid material.
Claim 7
Dependent Claim
21 words
The nozzle of claim 4, wherein said filter is formed of an elastic material harder than that of said inner tube.
Claim 8
Dependent Claim
25 words
The nozzle of claim 1, including granular beads in said reaction chamber, said granular beads having surfaces capable of supporting an antigen-antibody reaction product complex.
Claim 9
Dependent Claim
22 words
The nozzle of claim 7, wherein said nozzle device comprises a washing liquid supply and exhaust means of said biochemical reaction apparatus.
Claim 10
Dependent Claim
79 words
The nozzle of claim 8, wherein said means for inserting comprise: a movable supporting frame having at least one sleeve; one of said nozzles mounted in each said sleeve for vertical movement; means for biasing each said nozzle downwards; and stop means for limiting a downward movement of each said nozzle, whereby contact between said filter and said beads in said reaction chamber causes each said nozzle to lift off said stop means in opposition to said biasing means.
References Cited (Backward Citations)
US3846077A
Cited
US4212845A
Cited
US4321327A
Cited
US4590165A
Cited
US4635665A
Cited
US4699884A
Cited
US4586546A
Cited
US4644807A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-03-27 | 1992-09-26 | 1993-03-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-03-27 | 1996-09-26 | 1997-03-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-03-27 | 2000-09-26 | 2001-03-28 | $7700.00 | Window Closed / Lapsed |