Patent US4810634A successfully refreshed from Google Patents.
US4810634A
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US
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Pseudorabies virus mutants incapable of producing glycoprotein X
Assignee: Pharmacia and Upjohn Co
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Filing: 1986-06-17
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Granted: 1989-03-07
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Expires: 2006-06-17
Abstract
Abstract Provided are a virus vaccine, comprising a properly incapacitated virus lacking an antigen of the wild-type virus which is useful for serologically distinguishing between vaccinated and infected animals, methods for distinguishing between vaccinated and infected animals and multivalent vaccines.
Inventors
- 👤 Leonard E. Post
- 👤 Darrell R. Thomsen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 18:17
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/12; A61K39/245; A61P; A61P31/00; A61P31/12; A61P31/20; A61P31/22; C; C07; C07K; C07K14/00; C07K14/005; C12; C12N; C12N15/00; C12N7/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56983; A61K2039/51; A61K2039/525; A61K2039/5252; A61K2039/55; A61K2039/552; A61K2039/70; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16721; C12N2710/16722; C12N2710/16734; Y; Y10; Y10S; Y10S530/00; Y10S530/82; Y10S530/826
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
27 words
A non-naturally occurring pseudorabies virus, characterized in that upon replication it produces no glycoprotein X (gX) as a result of the viral DNA being altered or deleted.
Claim 2
Dependent Claim
27 words
A non-naturally occurring pseudorabies virus, characterized in that upon replication it produces no glycoprotein X (gX) as a result of the viral DNA being altered or deleted.
Claim 3
Dependent Claim
32 words
A pseudorabies virus according to claim 1, wherein said virus produces no gX as a result of a deletion, an insertion or both a deletion and an insertion in the gX gene.
Claim 4
Dependent Claim
14 words
A pseudorabies virus according to claim 2, having a deletion in the gX gene.
Claim 5
Dependent Claim
14 words
A pseudorabies virus according to claim 2, having an insertion in the gX gene.
Claim 6
Dependent Claim
15 words
A pseudorabies virus according to claim 1, wherein the virus produces no functional thymidine kinase.
Claim 7
Dependent Claim
15 words
A pseudorabies virus according to claim 2, wherein the virus produces no functional thymidine kinase.
Claim 8
Dependent Claim
15 words
A pseudorabies virus according to claim 3, wherein the virus produces no functional thymidine kinase.
Claim 9
Dependent Claim
15 words
A pseudorabies virus according to claim 4, wherein the virus produces no functional thymidine kinase.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-03-06 | 1992-09-05 | 1993-03-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-03-06 | 1996-09-05 | 1997-03-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-03-06 | 2000-09-05 | 2001-03-07 | $7700.00 | Window Closed / Lapsed |