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US4806340A Expired / Lapsed US ⏱️ 0.0 years remaining

Anticalculus oral composition

Assignee: Colgate Palmolive Co
•
Filing: 1986-03-20
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Granted: 1989-02-21
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Expires: 2006-03-20
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Abstract

Abstract An oral dentifrice composition such as a toothpaste, dental gel, toothpowder, dental tablet or lozenge containing as anticalculus agent about 4.3% to about 7% of alkali metal pyrophosphates comprising at least 4.3% of tetrapotassium pyrophosphate alone or admixed with up to 2.7% of tetrasodium pyrophosphate, and as inhibitors against enzymatic hydrolysis of such agent in saliva, a fluoride and preferably up to about 3% of a synthetic anionic polymeric polycarboxylate, and use of such composition in a program of oral hygiene and/or for inhibiting dental calculus.

Inventors

  • 👤 Abdul Gaffar
  • 👤 Thomas G. Polefka
  • 👤 Robert J. Ferlauto, Jr.
  • 👤 Rosemarie M. Crisafulli

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 19:51
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/30; A61K8/33; A61K8/39; A61K8/20; A61K8/21; A61K8/24; A61K8/25; A61K8/72; A61K8/81; A61K8/8164; A61K8/90; A61Q; A61Q11/00

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 126 words
In a method of inhibitng dental calculus by applying to the teeth a dentifrice composition in the form of a toothpaste, dental gel, toothpowder, dental tablet or lozenge and containing in an orally acceptable vehicle tetrapotassium pyrophosphate or mixtures of tetrapotassiuim and tetrasodium pyrophosphates as essential anticalculus agents, and an amount of a fluoride ion source sufficient to supply about 25 ppm to about 5,000 ppm of fluoride ion, the improvement whereby salivary hydrolysis of pyrophosphate by alkaline phosphatase is inhibited consisting essentially of including in said dentifrice composition an effective inhibiting amount therefor within the range of about 0.05 to about 3 wt. % of a syntehtic anionic polymeric polycarboxylate, said dentifrice composition being substantially free from solid gritty particles composed of undissolved tetrasodium pyrophosphate.
Claim 2
Dependent Claim 126 words
In a method of inhibitng dental calculus by applying to the teeth a dentifrice composition in the form of a toothpaste, dental gel, toothpowder, dental tablet or lozenge and containing in an orally acceptable vehicle tetrapotassium pyrophosphate or mixtures of tetrapotassiuim and tetrasodium pyrophosphates as essential anticalculus agents, and an amount of a fluoride ion source sufficient to supply about 25 ppm to about 5,000 ppm of fluoride ion, the improvement whereby salivary hydrolysis of pyrophosphate by alkaline phosphatase is inhibited consisting essentially of including in said dentifrice composition an effective inhibiting amount therefor within the range of about 0.05 to about 3 wt. % of a syntehtic anionic polymeric polycarboxylate, said dentifrice composition being substantially free from solid gritty particles composed of undissolved tetrasodium pyrophosphate.
Claim 3
Dependent Claim 44 words
A method according to claim 1 wherein said composition contains about 4.3 to about 7 wt. % of alkali metal pyrophosphate comprising at least about 4.3 wt. % of tetrapotassium pyrophosphate alone or admixed with up to about 2.7 wt. % of tetrasodium pyrophosphate.
Claim 4
Dependent Claim 23 words
A method according to claim 2 wherein said composition cotains tetrapotassium and tetrasoidum pyrophosphates in an approximate weight ratio of 4.3:2.7 to 6:1.
Claim 5
Dependent Claim 13 words
A method according to claim 3 wherein said approximate weight ratio is 4.5:1.5.
Claim 6
Independent Claim 25 words
A method according to any one of claims 1 to 3 wherein said polymeric olycarboxylate has a molecular weight of about 1,000 to about 1,000,000.
Claim 7
Dependent Claim 16 words
A method according to claim 5 wherein said molecular weight is about 30,000 to about 1,000,000.
Claim 8
Dependent Claim 16 words
A method according to claim 5 wherein said molecular weight is about 50,000 to about 300,000.
Claim 9
Independent Claim 32 words
A method according to any one of claims 1 to 7 wherein said polymeric polycarboxylate is a 1:4 to 4:1 copolymer of maleic anhydride or acid with another polymerizable ethylenically unsaturated monomer.
Claim 10
Dependent Claim 13 words
A method according to claim 8 wherein said monomer is methyl vinyl ether.
Claim 11
Dependent Claim 17 words
A method according to claim 9 wherein the said copolymer has a molecular weight of about 70,000.
Claim 12
Independent Claim 22 words
A method according to any of claims 1 to 10 wherein said composition has a pH of about 4.5 to about 10.
Claim 13
Independent Claim 20 words
A method according to any of claims 1 to 11 wherein said fluoride source comprises sodium fluoride or sodium monofluorophosphate.
Claim 14
Independent Claim 28 words
A method according to any one of claims 1 to 12 wherein said composition is in the form of a toothpaste further containing a dentally acceptable polishing agent.
Claim 15
Independent Claim 29 words
A method according to any one of claims 1 to 12 wherein said composition is in the form of a dental gel further containing a dentally acceptable polishing agent.
Claim 16
Independent Claim 21 words
A method according to any one of claims 1 to 12 wherein said composition is in the form of a lozenge.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-02-21 1992-08-22 1993-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-02-21 1996-08-22 1997-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-02-21 2000-08-22 2001-02-21 $7700.00 Window Closed / Lapsed

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