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US4801444A Expired / Lapsed US ⏱️ 0.0 years remaining

Medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis

Assignee: POLTAVSKY MEDITSINSKY STOMATOLOGICHESKY INSTITUT USSR POLTAVA ULITSA SHEVCHENKO 23
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Filing: 1988-03-03
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Granted: 1989-01-31
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Expires: 2008-03-03
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Abstract

Abstract A medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis comprises an efficient quantity of an active principle which is essentially a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: - -<IMAGE> - dimethylsulphoxide and a pharmaceutical excipient. Polyethyleneglycol having a molecular mass of 400 is recommended to be used as the pharmaceutical excipient. A method for treatment of urogenital trichomoniasis consists in application of the medicinal preparation in question to the mucosa of human genitalia in a dose of 1.5 to 10 ml twice a day for 5 to 7 days.

Inventors

  • 👤 Vladimir G. Kravchenko

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 16:52
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/11; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K9/0034; A61P; A61P13/00; A61P13/02; A61P15/00; A61P33/00; A61P33/02

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 42 words
A medicinal preparation comprising an effective amount of an active principal sufficient to prevent venereal diseases and for treatment of urogenital trichomoniasis which is comprised of a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: ##STR6##dimethylsulphoxide and the pharmaceutical excipient polyethylene glycol.
Claim 2
Dependent Claim 42 words
A medicinal preparation comprising an effective amount of an active principal sufficient to prevent venereal diseases and for treatment of urogenital trichomoniasis which is comprised of a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: ##STR6##dimethylsulphoxide and the pharmaceutical excipient polyethylene glycol.
Claim 3
Dependent Claim 21 words
A medicinal preparation as claimed in claim 1, which comprises polyethyleneglycol having a molecular mass of 400 as the pharmaceutical excipient.
Claim 4
Dependent Claim 47 words
A medicinal preparation as claimed in claim 2 in a liquid form, which comprises the aforesaid ingredients in the following ration in mass percent: ______________________________________ para-nitro-alpha-chlorocinnamic 0.3 aldehyde of the aformentioned formula dimethylsulphoxide 5.0 polyethyleneglycol with a molecu- to make up lar mass of 400 100 ______________________________________
Claim 5
Dependent Claim 87 words
A medicinal preparation as claimed in claim 2 in a liquid form dispensed in aerosol containers under pressure, which comprises additionally a surfactant and water, its ingredients being taken in the following ratio in mass percent: ______________________________________ para-nitro-alpha-chlorocinnamic 0.3 aldehyde of the aformentioned formula dimethylsulphoxide 5.0 polyethyleneglycol with a molecular 10 to 30 mass of 400 surfactant 3.0 to 6.0 water to make up 100 ______________________________________ as well as a propellant taken in an amount of 3 to 10 percent of a total mass of the ingredients.
Claim 6
Dependent Claim 32 words
A method for treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 1.
Claim 7
Dependent Claim 32 words
A method of treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 2.
Claim 8
Dependent Claim 32 words
A method of treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 3.
Claim 9
Dependent Claim 22 words
The method of claim 5, wherein the medicinal preparation is applied in a dose of from about 1.5 to about 10 ml.
Claim 10
Dependent Claim 38 words
The method of claim 8, wherein the medicinal preparation is applied in a dose of from about 1.5 to about 10 ml. per day, twice a day, over a period of from about 5 to about 7 days.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-01-31 1992-08-01 1993-01-31 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-01-31 1996-08-01 1997-01-31 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-01-31 2000-08-01 2001-01-31 $7700.00 Window Closed / Lapsed

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