US4801444A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis
Assignee: POLTAVSKY MEDITSINSKY STOMATOLOGICHESKY INSTITUT USSR POLTAVA ULITSA SHEVCHENKO 23
•
Filing: 1988-03-03
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Granted: 1989-01-31
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Expires: 2008-03-03
Abstract
Abstract A medicinal preparation for individual prevention of venereal diseases and treatment of urogenital trichomoniasis comprises an efficient quantity of an active principle which is essentially a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: - -<IMAGE> - dimethylsulphoxide and a pharmaceutical excipient. Polyethyleneglycol having a molecular mass of 400 is recommended to be used as the pharmaceutical excipient. A method for treatment of urogenital trichomoniasis consists in application of the medicinal preparation in question to the mucosa of human genitalia in a dose of 1.5 to 10 ml twice a day for 5 to 7 days.
Inventors
- 👤 Vladimir G. Kravchenko
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 16:52
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/11; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K9/0034; A61P; A61P13/00; A61P13/02; A61P15/00; A61P33/00; A61P33/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
42 words
A medicinal preparation comprising an effective amount of an active principal sufficient to prevent venereal diseases and for treatment of urogenital trichomoniasis which is comprised of a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: ##STR6##dimethylsulphoxide and the pharmaceutical excipient polyethylene glycol.
Claim 2
Dependent Claim
42 words
A medicinal preparation comprising an effective amount of an active principal sufficient to prevent venereal diseases and for treatment of urogenital trichomoniasis which is comprised of a synergistic mixture of para-nitro-alpha-chlorocinnamic aldehyde of the formula: ##STR6##dimethylsulphoxide and the pharmaceutical excipient polyethylene glycol.
Claim 3
Dependent Claim
21 words
A medicinal preparation as claimed in claim 1, which comprises polyethyleneglycol having a molecular mass of 400 as the pharmaceutical excipient.
Claim 4
Dependent Claim
47 words
A medicinal preparation as claimed in claim 2 in a liquid form, which comprises the aforesaid ingredients in the following ration in mass percent: ______________________________________
para-nitro-alpha-chlorocinnamic
0.3
aldehyde of the aformentioned formula
dimethylsulphoxide 5.0
polyethyleneglycol with a molecu-
to make up
lar mass of 400 100
______________________________________
Claim 5
Dependent Claim
87 words
A medicinal preparation as claimed in claim 2 in a liquid form dispensed in aerosol containers under pressure, which comprises additionally a surfactant and water, its ingredients being taken in the following ratio in mass percent: ______________________________________
para-nitro-alpha-chlorocinnamic
0.3
aldehyde of the aformentioned formula
dimethylsulphoxide 5.0
polyethyleneglycol with a molecular
10 to 30
mass of 400
surfactant 3.0 to 6.0
water to make up
100
______________________________________ as well as a propellant taken in an amount of 3 to 10 percent of a total mass of the ingredients.
Claim 6
Dependent Claim
32 words
A method for treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 1.
Claim 7
Dependent Claim
32 words
A method of treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 2.
Claim 8
Dependent Claim
32 words
A method of treating urogenital trichomoniasis in a subject which comprises applying to the mucosa of the genitalia of said subject, a therapeutically effective amount of the medicinal preparation of claim 3.
Claim 9
Dependent Claim
22 words
The method of claim 5, wherein the medicinal preparation is applied in a dose of from about 1.5 to about 10 ml.
Claim 10
Dependent Claim
38 words
The method of claim 8, wherein the medicinal preparation is applied in a dose of from about 1.5 to about 10 ml. per day, twice a day, over a period of from about 5 to about 7 days.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-01-31 | 1992-08-01 | 1993-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-01-31 | 1996-08-01 | 1997-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-01-31 | 2000-08-01 | 2001-01-31 | $7700.00 | Window Closed / Lapsed |